DDrare: Database of Drug Development for Rare Diseases

Lactulose (DrugBank: Lactulose)

2 diseases

ID	Disease name (Link within this page)	Number of trials
96	Crohn disease	1
291	Hirschsprung disease, entire colon type	1

96. Crohn disease [ 2,209 clinical trials, 1,276 drugs, (DrugBank: 240 drugs), 166 drug target genes, 210 drug target pathways]

Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 2,209 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03962998 (ClinicalTrials.gov)	October 27, 2019	22/5/2019	Oral Administration of MB-102 Versus Dual Sugar Testing for Gut Permeability	A Randomized Unblinded Feasibility Study Evaluating the Use of Oral Administration of MB-102 Versus Dual Sugar Testing for Gut Permeability in Normal Subjects and Subjects With Active Small Bowel Crohn's Disease	Crohn Disease	Drug: Lactulose/Rhamnose solution;Drug: MB-102	MediBeacon	NULL	Recruiting	18 Years	N/A	All	20	Early Phase 1	United States

291. Hirschsprung disease, entire colon type [ 13 clinical trials, 32 drugs, (DrugBank: 15 drugs), 0 drug target gene, 0 drug target pathway]

Searched query = "Hirschsprung disease, entire colon type", "Hirschsprung disease, small intestine type", "Hirschsprung disease", "Hirschprung disease", "Hirschsprung disease associated entercolitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 13 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02216994 (ClinicalTrials.gov)	January 2013	6/8/2014	A New Scoring System Improves Diagnostic Accuracy of Intestinal Dysganglionosis --a Prospective Study	Efficacy and Accuracy of a New Diagnostic Scoring System to Differentiate Hirschsprung Disease From Hirschsprung Disease Allied Disorders in the Patients With Suspected Intestinal Dysganglinosis: a Prospective Study	Hirschsprung Disease	Drug: high dose lactulose;Behavioral: conservative treatment;Drug: paraffin oil	Tongji Hospital	Jiangxi Provincial Children's Hospital	Recruiting	N/A	3 Years	Both	80	N/A	China