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   e.g. "Sirolimus", "Adalimumab"

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43 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG *   KEGG GENES * 
 [Number of genes] 		  KEGG PATHWAY 
 [Number of pathways] 		  Disease ID * 
 [Number of diseases] 
 1   Any other approved aed   -   -   -   -   [1]
144 
 2   Cannabidiol   Cannabidiol   D10915   [2] CNR1, CNR2   [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis   [13]
6,
13,
46,
95,
96,
97,
140,
144,
145,
157,
158,
193,
271 
 3   Cannabidiol oral solution   Cannabidiol   D10915   [2] CNR1, CNR2   [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis   [4]
140,
144,
145,
193 
 4   Carisbamate   Carisbamate   D06573   -   -   [1]
144 
 5   Clobazam   Clobazam   D01253   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [2]
140,
144 
 6   Clobazam high dose   Clobazam   D01253   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
144 
 7   Clobazam low dose   Clobazam   D01253   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
144 
 8   Clobazam medium dose   Clobazam   D01253   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
144 
 9   Clobazam pheur   Clobazam   D01253   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
144 
 10   Clobazam tablets   Clobazam   D01253   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
144 
 11   Clobazam tablets 10mg   Clobazam   D01253   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
144 
 12   Clobazam tablets 20mg   Clobazam   D01253   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
144 
 13   Clobazam tablets 5mg   Clobazam   D01253   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
144 
 14   E2007   -   -   -   -   [2]
6,
144 
 15   E2080   -   -   -   -   [1]
144 
 16   Ezogabine   Ezogabine   D09569   [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5   [6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection   [2]
2,
144 
 17   Ezogabine (us only)   Ezogabine   D09569   [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5   [6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection   [1]
144 
 18   Ezogabine/retigabine   Ezogabine   D09569   [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5   [6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection   [1]
144 
 19   Fenfluramine   Fenfluramine   D04148, D07945   [4] HTR2A, HTR2B, HTR2C, SLC6A4   [6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle   [2]
140,
144 
 20   Fenfluramine hcl, dl-fenfluramine, (±)-fenfluramine   Fenfluramine   D04148, D07945   [4] HTR2A, HTR2B, HTR2C, SLC6A4   [6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle   [1]
144 
 21   Fenfluramine hydrochloride   Fenfluramine   D04148, D07945   [4] HTR2A, HTR2B, HTR2C, SLC6A4   [6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle   [2]
140,
144 
 22   Fycompa   Perampanel   D08964   [4] GRIA1, GRIA2, GRIA3, GRIA4   [13] Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Transcriptional misregulation in cancer, cAMP signaling pathway   [2]
2,
144 
 23   Gw582892   -   -   -   -   [1]
144 
 24   Gwp42003-p   -   -   -   -   [5]
140,
144,
145,
156,
158 
 25   Gwp42003-p 20 mg/kg/day dose   -   -   -   -   [1]
144 
 26   Investigators choice of approved aed   -   -   -   -   [1]
144 
 27   Investigators choice of approved aeds   -   -   -   -   [1]
144 
 28   Melatonin   Melatonin   D08170   [2] MTNR1A, MTNR1B   [2] Circadian entrainment, Neuroactive ligand-receptor interaction   [8]
6,
13,
46,
49,
90,
97,
144,
202 
 29   Perampanel   Perampanel   D08964   [4] GRIA1, GRIA2, GRIA3, GRIA4   [13] Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Transcriptional misregulation in cancer, cAMP signaling pathway   [3]
2,
6,
144 
 30   Placebo   -   -   -   -   [20]
3,
6,
13,
14,
40,
46,
49,
50,
51,
66,
67,
79,
85,
86,
88,
96,
97,
144,
149,
226 
 31   Potiga   Ezogabine   D09569   [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5   [6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection   [1]
144 
 32   Retigabine   Ezogabine   D09569   [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5   [6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection   [2]
2,
144 
 33   Retigabine/ezogabine   Ezogabine   D09569   [5] KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5   [6] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection   [1]
144 
 34   Rufinamide   Rufinamide   D05775   [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction   [1]
144 
 35   Rufinamide (e2080)   Rufinamide   D05775   [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction   [1]
144 
 36   Rufinamide oral suspension   Rufinamide   D05775   [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction   [1]
144 
 37   Rufinamide(inovelon)   Rufinamide   D05775   [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction   [1]
144 
 38   Tak-935   -   -   -   -   [2]
140,
144 
 39   Topiramate   Topiramate   D00537   [36] CA2, CA4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [48] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [5]
6,
140,
144,
156,
193 
 40   Turmeric   Turmeric   -   -   -   [4]
140,
144,
158,
299 
 41   Zx008 (fenfluramine hydrochloride)   Fenfluramine   D04148, D07945   [4] HTR2A, HTR2B, HTR2C, SLC6A4   [6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle   [2]
140,
144 
 42   Zx008 0.2 and 0.8 mg/kg/day   -   -   -   -   [2]
140,
144 
 43   Zx008 0.2 or 0.8 mg/kg/day   -   -   -   -   [1]
144 

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