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   e.g. "Sirolimus", "Adalimumab"

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65 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG  KEGG GENES
 [Number of genes] 
 KEGG PATHWAY 
 [Number of pathways] 
 Disease ID
 [Number of diseases] 
 1   Abatacept   Abatacept   D03203   [2] CD80, CD86   [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis   [24]
11,
13,
19,
41,
44,
46,
49,
50,
51,
53,
55,
60,
65,
84,
93,
96,
97,
107,
164,
222,
271,
284,
285,
300 
 2   Alefacept   Alefacept   D02800   [1] CD58   [2] Cell adhesion molecules (CAMs), Epstein-Barr virus infection   [6]
37,
60,
65,
164,
284,
285 
 3   Amd3100   -   -   -   -   [1]
285 
 4   Anti-cd45   -   -   -   -   [3]
60,
65,
285 
 5   Anti-thymocyte globulin   -   -   -   -   [18]
11,
13,
14,
36,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
164,
283,
284,
285 
 6   Anti-thymocyte globulin (rabbit)   Rabbit   -   -   -   [3]
60,
65,
285 
 7   Ap1903   Ap1903   -   -   -   [3]
60,
285,
326 
 8   Bpx-501 t cells   -   -   -   -   [4]
65,
284,
285,
326 
 9   Busulfan   Busulfan   D00248   -   -   [13]
19,
20,
28,
36,
49,
51,
60,
65,
164,
274,
284,
285,
326 
 10   Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.   Cyclophosphamide   D00287, D07760   -   -   [2]
60,
285 
 11   Campath 1h   Alemtuzumab   D02802   -   -   [4]
60,
65,
164,
285 
 12   Campath-1h   Alemtuzumab   D02802   -   -   [6]
19,
20,
60,
234,
285,
326 
 13   Cd34+ cells   -   -   -   -   [1]
285 
 14   Cd34+ selected cells   -   -   -   -   [1]
285 
 15   Cd34+cells   -   -   -   -   [2]
65,
285 
 16   Chemotherapy   -   -   -   -   [3]
28,
60,
285 
 17   Cyclophosphamide   Cyclophosphamide   D00287, D07760   -   -   [43]
13,
14,
16,
19,
20,
26,
28,
35,
36,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
52,
56,
60,
61,
62,
65,
66,
84,
85,
93,
96,
162,
164,
172,
222,
224,
265,
274,
283,
284,
285,
288,
326,
331 
 18   Cyclophosphamide (cy) (plan 1)   Cyclophosphamide   D00287, D07760   -   -   [2]
60,
285 
 19   Cyclophosphamide (cy) (plan 2)   Cyclophosphamide   D00287, D07760   -   -   [2]
60,
285 
 20   Cyclophosphamide 30   Cyclophosphamide   D00287, D07760   -   -   [3]
65,
285,
326 
 21   Cyclophosphamide 40   Cyclophosphamide   D00287, D07760   -   -   [3]
65,
285,
326 
 22   Cyclophosphamide, fludarabine   Cyclophosphamide   D00287, D07760   -   -   [1]
285 
 23   Cyclosporine   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [33]
11,
14,
19,
20,
28,
36,
40,
41,
42,
45,
46,
49,
50,
53,
56,
58,
60,
62,
64,
65,
90,
95,
97,
162,
164,
222,
226,
228,
234,
283,
284,
285,
302 
 24   Danazol   Danazol   D00289   [3] AR, ESR1, PGR   [11] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway   [4]
60,
64,
65,
285 
 25   Eltrombopag   Eltrombopag   D03978   -   -   [3]
60,
63,
285 
 26   Enbrel*sc 4fl 25mg+4sir 1ml   Etanercept   D00742   [2] LTA, TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [2]
60,
285 
 27   Etanercept   Etanercept   D00742   [2] LTA, TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [14]
15,
35,
38,
39,
46,
50,
53,
56,
60,
85,
228,
271,
285,
298 
 28   Filgrastim   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [25]
2,
6,
13,
25,
26,
28,
34,
35,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
96,
113,
164,
283,
284,
285,
331 
 29   Fludarabine   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [17]
13,
28,
36,
46,
49,
51,
60,
61,
62,
65,
85,
96,
164,
283,
284,
285,
326 
 30   Fludarabine (flu)   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [2]
60,
285 
 31   Fludarabine phosphate   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [11]
28,
36,
49,
51,
60,
62,
65,
96,
283,
284,
285 
 32   G-csf   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [12]
6,
13,
16,
49,
51,
60,
65,
85,
96,
284,
285,
331 
 33   Genetically engineered hematopoietic stem progenitor cells   -   -   -   -   [1]
285 
 34   Genetically engineered hematopoietic stem/progenitor cells   -   -   -   -   [1]
285 
 35   Hematopoietic stem cell transplantation   -   -   -   -   [12]
11,
13,
14,
19,
20,
35,
46,
49,
51,
96,
234,
285 
 36   Melphalan   Melphalan   D00369   -   -   [14]
11,
13,
14,
19,
20,
28,
60,
62,
65,
96,
164,
234,
284,
285 
 37   Metformin   Metformin   D00944, D04966   [2] PRKAA1, PRKAA2   [19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway   [16]
6,
13,
46,
49,
67,
75,
77,
81,
86,
113,
158,
206,
225,
233,
265,
285 
 38   Metformin hcl   Metformin   D00944, D04966   [2] PRKAA1, PRKAA2   [19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway   [1]
285 
 39   Methotrexate   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [33]
11,
13,
19,
34,
35,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
55,
56,
60,
62,
65,
84,
93,
96,
97,
162,
164,
172,
256,
271,
284,
285,
326,
331 
 40   Methylprednisolone   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [36]
2,
13,
25,
26,
35,
38,
39,
40,
41,
42,
43,
45,
46,
49,
50,
51,
60,
63,
64,
65,
66,
83,
84,
86,
96,
97,
145,
164,
220,
222,
224,
271,
283,
284,
285,
296 
 41   Methylprednisolone (mp)   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [2]
60,
285 
 42   Miltenyi clinimacs   -   -   -   -   [1]
285 
 43   Mozobil   Plerixafor   D08971   [1] CXCR4   [12] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral protein interaction with cytokine and cytokine receptor   [1]
285 
 44   Mycophenolate   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [33]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
84,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 45   Mycophenolate mofetil   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [32]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 46   Neupogen   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [4]
13,
28,
51,
285 
 47   Oxandrolone   Oxandrolone   D00462   [1] AR   [3] Oocyte meiosis, Pathways in cancer, Prostate cancer   [2]
211,
285 
 48   Peripheral blood stem cell   -   -   -   -   [1]
285 
 49   Phosphate   Phosphate ion   -   -   -   [29]
2,
3,
11,
12,
13,
28,
36,
46,
49,
51,
53,
60,
62,
65,
70,
78,
81,
83,
90,
96,
97,
164,
235,
256,
283,
284,
285,
286,
299 
 50   Plerixafor   Plerixafor   D08971   [1] CXCR4   [12] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral protein interaction with cytokine and cytokine receptor   [4]
51,
65,
285,
299 
 51   Plérixafor   -   -   -   -   [1]
285 
 52   Prednisone   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [43]
2,
11,
13,
14,
26,
35,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
61,
63,
64,
65,
66,
81,
84,
85,
86,
95,
96,
97,
113,
162,
164,
222,
224,
228,
251,
283,
284,
285,
288,
299,
300,
331 
 53   Quercetin   Quercetin   -   -   -   [5]
84,
85,
192,
285,
299 
 54   Quercetin (dietary supplement)   Quercetin   -   -   -   [1]
285 
 55   Rabbit   Rabbit   -   -   -   [7]
13,
49,
51,
60,
65,
96,
285 
 56   Rabbit atg   Rabbit   -   -   -   [2]
60,
285 
 57   Rimiducid   -   -   -   -   [5]
19,
65,
284,
285,
326 
 58   Rituximab   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [42]
11,
13,
14,
17,
35,
36,
43,
44,
45,
46,
49,
50,
51,
52,
53,
56,
60,
61,
63,
64,
65,
66,
83,
84,
85,
86,
93,
94,
96,
97,
162,
222,
223,
229,
256,
271,
283,
284,
285,
288,
300,
331 
 59   Rivogenlecleucel   -   -   -   -   [4]
19,
65,
284,
285 
 60   Rp-l102   -   -   -   -   [1]
285 
 61   Sirolimus   Sirolimus   D00753   [1] MTOR   [43] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway   [30]
13,
17,
34,
35,
36,
46,
51,
60,
62,
63,
65,
66,
67,
85,
89,
96,
98,
137,
157,
158,
192,
222,
277,
278,
279,
280,
281,
283,
285,
331 
 62   T cell infusion   -   -   -   -   [1]
285 
 63   Total body irradiation (tbi) (plan 1)   -   -   -   -   [2]
60,
285 
 64   Transduced cd34+ cells   -   -   -   -   [1]
285 
 65   Zarzio   -   -   -   -   [1]
285 

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