No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
Carbidopa |
Carbidopa |
D00558 |
[1] DDC |
[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism |
[8] 2, 4, 6, 13, 17, 90, 164, 201 |
2 |
Carbidopa-levodopa |
Carbidopa |
D00558 |
[1] DDC |
[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism |
[3] 2, 4, 6 |
3 |
Dalfampridine |
Dalfampridine |
D04127 |
[2] KCNA4, KCND2 |
[3] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse |
[2] 4, 13 |
4 |
Daraprim |
Pyrimethamine |
D00488 |
- |
- |
[2] 2, 4 |
5 |
Dexdor |
- |
- |
- |
- |
[4] 2, 4, 6, 70 |
6 |
Dexmedetomidine |
Dexmedetomidine |
D00514, D01205 |
[3] ADRA2A, ADRA2B, ADRA2C |
[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway |
[11] 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
7 |
Esketamine |
Esketamine |
D07283 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
[17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway |
[3] 2, 4, 70 |
8 |
Ketanest-s |
- |
- |
- |
- |
[3] 2, 4, 70 |
9 |
Levetiracetam |
Levetiracetam |
D00709 |
[1] SV2A |
[1] ECM-receptor interaction |
[4] 2, 4, 6, 13 |
10 |
Levodopa |
Levodopa |
D00059 |
[5] DRD1, DRD2, DRD3, DRD4, DRD5 |
[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway |
[7] 2, 4, 6, 17, 90, 164, 201 |
11 |
Pyrimethamine |
Pyrimethamine |
D00488 |
- |
- |
[4] 2, 4, 19, 65 |
12 |
Stem cells |
- |
- |
- |
- |
[4] 2, 4, 96, 113 |