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   e.g. "Sirolimus", "Adalimumab"

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477 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG  KEGG GENES
 [Number of genes] 
 KEGG PATHWAY 
 [Number of pathways] 
 Disease ID
 [Number of diseases] 
 1   1 mg/kg cnto 136   -   -   -   -   [1]
49 
 2   10 mg/kg cnto 136   -   -   -   -   [1]
49 
 3   2-deoxy-2 [f-18] fluoro-2-d-glucose   D-glucose   D00009   -   -   [1]
49 
 4   4 mg/kg cnto 136   -   -   -   -   [1]
49 
 5   81mg aspirin   Acetylsalicylic acid   D00109   [2] PTGS1, PTGS2   [21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway   [1]
49 
 6   A-623   -   -   -   -   [1]
49 
 7   Abatacept   Abatacept   D03203   [2] CD80, CD86   [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis   [24]
11,
13,
19,
41,
44,
46,
49,
50,
51,
53,
55,
60,
65,
84,
93,
96,
97,
107,
164,
222,
271,
284,
285,
300 
 8   Abbv-105   -   -   -   -   [2]
46,
49 
 9   Abetimus   Abetimus   -   -   -   [1]
49 
 10   Abetimus sodium   Abetimus   -   -   -   [1]
49 
 11   Abetimus sodium (ljp 394)   Abetimus   -   -   -   [1]
49 
 12   Abr-215757   -   -   -   -   [2]
49,
51 
 13   Abt-199   -   -   -   -   [1]
49 
 14   Ac0058ta   -   -   -   -   [1]
49 
 15   Acetaminophen   Acetaminophen   D00217   [2] PTGS1, PTGS2   [21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway   [11]
13,
34,
35,
46,
49,
51,
70,
86,
231,
256,
271 
 16   Acetate   Acetate   -   -   -   [40]
1,
2,
6,
10,
13,
35,
40,
46,
49,
51,
60,
64,
70,
71,
73,
75,
76,
78,
81,
83,
85,
86,
88,
90,
96,
97,
113,
145,
156,
162,
171,
206,
222,
224,
225,
235,
265,
288,
298,
299 
 17   Acetylcysteine   Acetylcysteine   D00221   -   -   [14]
6,
13,
19,
20,
49,
51,
58,
85,
94,
111,
164,
233,
298,
299 
 18   Acido micofenolico   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [1]
49 
 19   Act-334441   -   -   -   -   [1]
49 
 20   Acthar   Corticotropin   D00146   [1] MC2R   [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [6]
2,
13,
46,
49,
50,
222 
 21   Acthar gel   -   -   -   -   [4]
13,
46,
49,
84 
 22   Acthar high dose (80 u)   -   -   -   -   [1]
49 
 23   Acthar low dose (40 u)   -   -   -   -   [1]
49 
 24   Ags-009   -   -   -   -   [1]
49 
 25   Aidsvax® b/e   -   -   -   -   [1]
49 
 26   Akbm-3031   -   -   -   -   [1]
49 
 27   Aldesleukin   Aldesleukin   D00748   [3] IL2RA, IL2RB, IL2RG   [14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease (IBD), JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor   [3]
49,
65,
97 
 28   Alfacalcidol   Alfacalcidol   D01518   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [6]
41,
46,
49,
50,
96,
235 
 29   Alitretinoin   Alitretinoin   D02815   [5] RARA, RARB, RXRA, RXRB, RXRG   [17] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Non-alcoholic fatty liver disease (NAFLD), Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer   [1]
49 
 30   Allogeneic mesenchymal stromal cells derived from the umbilical cord   -   -   -   -   [1]
49 
 31   Allogeneic msc (allomsc)   -   -   -   -   [1]
49 
 32   Allogeneic stem cell transplantation   -   -   -   -   [2]
49,
84 
 33   Alpha-tocopherol   Tocopherol   D02332   -   -   [1]
49 
 34   Alx-0061   -   -   -   -   [2]
46,
49 
 35   Amg 557   -   -   -   -   [1]
49 
 36   Amg 570   -   -   -   -   [2]
46,
49 
 37   Amg 592   -   -   -   -   [2]
46,
49 
 38   Amg 623   -   -   -   -   [1]
49 
 39   Amg 811   -   -   -   -   [1]
49 
 40   Amg811   -   -   -   -   [1]
49 
 41   Anakinra   Anakinra   D02934   [2] IL1R1, IL1R2   [15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer   [15]
2,
13,
15,
19,
37,
41,
46,
49,
50,
56,
84,
86,
106,
107,
299 
 42   Anifrolumab   Anifrolumab   D11082   [2] IFNAR1, IFNAR2   [17] Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway   [2]
46,
49 
 43   Anifrolumab 1000 mg   Anifrolumab   D11082   [2] IFNAR1, IFNAR2   [17] Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway   [1]
49 
 44   Anifrolumab 300 mg   Anifrolumab   D11082   [2] IFNAR1, IFNAR2   [17] Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway   [1]
49 
 45   Anti-cd19-car-t cells   -   -   -   -   [1]
49 
 46   Anti-cd20 b cell depletion with truxima   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [1]
49 
 47   Anti-macrophage migration inhibitory factor (anti-mif) antibody   -   -   -   -   [1]
49 
 48   Anti-pandemic h1n1 influenza vaccine   -   -   -   -   [5]
46,
49,
50,
51,
53 
 49   Anti-thymocyte globulin   -   -   -   -   [18]
11,
13,
14,
36,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
164,
283,
284,
285 
 50   Asf-1096 cream 0.25%   -   -   -   -   [1]
49 
 51   Asf-1096 cream 0.5%   -   -   -   -   [1]
49 
 52   Asf-1096 cream 1.0%   -   -   -   -   [1]
49 
 53   Aspirin   Acetylsalicylic acid   D00109   [2] PTGS1, PTGS2   [21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway   [10]
13,
22,
34,
46,
49,
51,
86,
113,
158,
231 
 54   Aspirin and meloxicam   Meloxicam   D00969   [1] PTGS2   [20] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway   [1]
49 
 55   Atacicept   Atacicept   D09704   [2] TNFSF13, TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [4]
13,
46,
49,
66 
 56   Atacicept 150 mg   Atacicept   D09704   [2] TNFSF13, TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [3]
13,
49,
66 
 57   Atacicept 75 mg   Atacicept   D09704   [2] TNFSF13, TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [3]
13,
49,
66 
 58   Atacicept 75 milligram (mg)   Atacicept   D09704   [2] TNFSF13, TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 59   Atorvastatin   Atorvastatin   D00258, D00887, D07474   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [17]
13,
46,
49,
51,
58,
63,
79,
84,
88,
93,
96,
160,
222,
225,
265,
271,
299 
 60   Autologous ebv specific ctl infusion   -   -   -   -   [1]
49 
 61   Aviptadil   Aviptadil   -   -   -   [4]
49,
51,
85,
86 
 62   Azathioprine   Azathioprine   D00238, D03033   -   -   [18]
11,
13,
19,
35,
42,
43,
44,
45,
46,
49,
65,
66,
85,
94,
95,
96,
97,
162 
 63   Baricitinib   Baricitinib   D10308   [2] JAK1, JAK2   [32] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis   [8]
41,
46,
49,
50,
93,
107,
265,
325 
 64   Belimumab   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [8]
11,
43,
44,
46,
49,
51,
53,
222 
 65   Belimumab 1 mg/kg   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [2]
46,
49 
 66   Belimumab 10 mg/kg   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [3]
43,
46,
49 
 67   Belimumab 10 mg/kg plus standard therapy   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 68   Belimumab 100 mg sc   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 69   Belimumab 10mg/kg   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 70   Belimumab 200 mg sc   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 71   Belimumab 200 mg/ml   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 72   Belimumab 4 mg/kg   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [2]
46,
49 
 73   Belimumab for iv   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 74   Belimumab for sc   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 75   Belimumab injection   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 76   Belimumab or benlysta   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 77   Belimumab plus early vaccination   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 78   Belimumab plus late vaccination   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 79   Benlysta   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 80   Benlysta (belimumab)   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [4]
11,
49,
53,
222 
 81   Benlysta 400 mg powder for concentrate for solution for infusion   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 82   Benlysta™ (belimumab)   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 83   Bi 705564   -   -   -   -   [1]
49 
 84   Biib059   -   -   -   -   [1]
49 
 85   Blisibimod   Blisibimod   D10311   -   -   [5]
43,
44,
49,
63,
66 
 86   Blood sample   -   -   -   -   [12]
8,
13,
46,
49,
51,
53,
61,
66,
97,
274,
288,
299 
 87   Bms-188667   Abatacept   D03203   [2] CD80, CD86   [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis   [6]
46,
49,
65,
96,
97,
271 
 88   Bms-931699   Lulizumab pegol   -   -   -   [2]
49,
53 
 89   Bms-986165   -   -   -   -   [3]
49,
96,
97 
 90   Bms-986165 capsule   -   -   -   -   [1]
49 
 91   Bms-986165 tablet   -   -   -   -   [1]
49 
 92   Bortezomib   Bortezomib   D03150   [1] PSMB5   [1] Proteasome   [13]
11,
26,
28,
46,
49,
51,
61,
63,
66,
228,
256,
288,
331 
 93   Bos161721   -   -   -   -   [1]
49 
 94   Br-dim   -   -   -   -   [1]
49 
 95   Brentuximab vedotin   Brentuximab vedotin   D09587   [10] TNFRSF8, TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8   [4] Cytokine-cytokine receptor interaction, Gap junction, Pathogenic Escherichia coli infection, Phagosome   [2]
49,
51 
 96   Bt063   -   -   -   -   [1]
49 
 97   Busulfan   Busulfan   D00248   -   -   [13]
19,
20,
28,
36,
49,
51,
60,
65,
164,
274,
284,
285,
326 
 98   Calcitriol   Calcitriol   D00129   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [8]
37,
46,
49,
66,
96,
158,
235,
326 
 99   Calcium   Calcium   -   -   -   [24]
6,
13,
19,
46,
49,
51,
65,
68,
75,
79,
84,
93,
94,
95,
96,
97,
214,
215,
222,
224,
235,
265,
298,
299 
 100   Campath   Alemtuzumab   D02802   -   -   [4]
49,
51,
60,
65 
 101   Cc-220   -   -   -   -   [2]
49,
84 
 102   Cdp3194   -   -   -   -   [1]
49 
 103   Cdp7657   -   -   -   -   [1]
49 
 104   Cellcept   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [3]
11,
42,
49 
 105   Cenerimod   Cenerimod   D11283   [1] S1PR1   [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway   [1]
49 
 106   Cenerimod 0.5 mg   Cenerimod   D11283   [1] S1PR1   [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway   [1]
49 
 107   Cenerimod 1 mg   Cenerimod   D11283   [1] S1PR1   [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway   [1]
49 
 108   Cenerimod 2 mg   Cenerimod   D11283   [1] S1PR1   [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway   [1]
49 
 109   Cenerimod 4 mg   Cenerimod   D11283   [1] S1PR1   [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway   [1]
49 
 110   Cep-33457   -   -   -   -   [1]
49 
 111   Cfz533   -   -   -   -   [4]
11,
46,
49,
53 
 112   Chloroquine   Chloroquine   D02125, D02366, D03469   -   -   [4]
46,
49,
95,
130 
 113   Cholecalciferol   Cholecalciferol   D00188   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [9]
13,
19,
34,
46,
49,
96,
97,
298,
299 
 114   Cholecalciferol and c. xanthorrhiza   Cholecalciferol   D00188   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [1]
49 
 115   Ciclosporin   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [13]
26,
46,
49,
50,
53,
55,
60,
61,
97,
222,
226,
228,
269 
 116   Ciclosporina   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [2]
49,
228 
 117   Clofarabine   Clofarabine   D03546   [3] POLA1, POLA2, RRM1   [6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [9]
19,
20,
40,
46,
49,
60,
96,
234,
326 
 118   Clopidogrel   Clopidogrel   D00769, D07729, D10823, D10824   [1] P2RY12   [1] Platelet activation   [2]
49,
86 
 119   Conjugated equine estrogens   Conjugated estrogens   D04070, D05987   -   -   [1]
49 
 120   Conjugated equine estrogens 0.625 mg/d + mpa 5 mg/d/10d   Conjugated estrogens   D04070, D05987   -   -   [1]
49 
 121   Continuation of azathioprine   Azathioprine   D00238, D03033   -   -   [1]
49 
 122   Corticosteroids   -   -   -   -   [9]
41,
46,
49,
64,
97,
164,
220,
296,
300 
 123   Corticosteroids (prednisone or prednisolone)   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
49 
 124   Creatine   Creatine   -   -   -   [12]
1,
2,
5,
6,
8,
13,
46,
49,
50,
113,
156,
201 
 125   Crestor   Rosuvastatin   D01915, D08492   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [3]
49,
79,
299 
 126   Csm allogéniques issues de cordons ombilicaux ( mti-pp)   Afamelanotide   D10511   -   -   [1]
49 
 127   Ctla4-igg4m (rg2077)   -   -   -   -   [1]
49 
 128   Ctla4ig   -   -   -   -   [4]
46,
49,
96,
271 
 129   Cumulative corticosteroid exposure   -   -   -   -   [1]
49 
 130   Curcumin   Curcumin   -   -   -   [10]
13,
46,
49,
67,
74,
94,
96,
97,
139,
299 
 131   Curcumin supplement   Curcumin   -   -   -   [1]
49 
 132   Cyclophosphamide   Cyclophosphamide   D00287, D07760   -   -   [43]
13,
14,
16,
19,
20,
26,
28,
35,
36,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
52,
56,
60,
61,
62,
65,
66,
84,
85,
93,
96,
162,
164,
172,
222,
224,
265,
274,
283,
284,
285,
288,
326,
331 
 133   Cyclophosphamide-prednisone-azathioprine   Cyclophosphamide   D00287, D07760   -   -   [1]
49 
 134   Cyclosporin   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [16]
14,
38,
39,
49,
53,
56,
60,
62,
63,
97,
113,
164,
222,
223,
274,
326 
 135   Cyclosporin a   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [11]
14,
38,
39,
49,
53,
56,
60,
62,
63,
113,
164 
 136   Cyclosporine   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [33]
11,
14,
19,
20,
28,
36,
40,
41,
42,
45,
46,
49,
50,
53,
56,
58,
60,
62,
64,
65,
90,
95,
97,
162,
164,
222,
226,
228,
234,
283,
284,
285,
302 
 137   Cyclosporine a   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [8]
19,
20,
36,
49,
53,
58,
60,
234 
 138   Cymbalta   Duloxetine   D01179, D07880   [2] SLC6A2, SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [3]
6,
13,
49 
 139   Cytarabine   Cytarabine   D00168, D03046, D03637   -   -   [6]
11,
13,
14,
25,
49,
60 
 140   D-glucose   D-glucose   D00009   -   -   [3]
49,
86,
88 
 141   Dapagliflozin   Dapagliflozin   D08897   -   -   [2]
49,
222 
 142   Dapirolizumab pegol   -   -   -   -   [1]
49 
 143   Dapirolizumab pegol (dzp)   -   -   -   -   [1]
49 
 144   Dehydroepiandrosterone   Prasterone   D08409   [3] AR, ESR1, ESR2   [11] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway   [5]
49,
53,
83,
96,
113 
 145   Dehydroepiandrosterone (dhea)   Prasterone   D08409   [3] AR, ESR1, ESR2   [11] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway   [1]
49 
 146   Dhea   Prasterone   D08409   [3] AR, ESR1, ESR2   [11] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway   [3]
49,
86,
96 
 147   Dihydroartemisinin   Artenimol   D07362   -   -   [1]
49 
 148   Dihydroartemisinin tablet   Artenimol   D07362   -   -   [1]
49 
 149   Dimethylfumarat   -   -   -   -   [1]
49 
 150   Diphenhydramine   Diphenhydramine   D00300, D00669, D02419, D03285, D03360, D03854   [1] HRH1   [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction   [5]
49,
51,
70,
86,
256 
 151   Dipyridamole   Dipyridamole   D00302   [2] PDE4A, PDE5A   [6] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway   [5]
46,
49,
51,
66,
224 
 152   Docosahexaenoic acid   Doconexent   -   -   -   [7]
6,
49,
90,
94,
240,
299,
301 
 153   Drug inducing arthritis, lupus, hepatitis, or capillary leak syndrom   -   -   -   -   [2]
46,
49 
 154   Edratide   Edratide   D03957   -   -   [1]
49 
 155   Eicosapentaenoic acid   Icosapent   D08061   -   -   [5]
49,
96,
97,
296,
297 
 156   Epa and dha supplementation   -   -   -   -   [2]
48,
49 
 157   Epratuzumab   Epratuzumab   D04036   [1] CD22   [3] B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage   [1]
49 
 158   Epratuzumab 100 mg   Epratuzumab   D04036   [1] CD22   [3] B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage   [1]
49 
 159   Epratuzumab 1200 mg   Epratuzumab   D04036   [1] CD22   [3] B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage   [1]
49 
 160   Epratuzumab 400 mg   Epratuzumab   D04036   [1] CD22   [3] B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage   [1]
49 
 161   Epratuzumab 600 mg   Epratuzumab   D04036   [1] CD22   [3] B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage   [1]
49 
 162   Epratuzumab iv   Epratuzumab   D04036   [1] CD22   [3] B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage   [1]
49 
 163   Epratuzumab sc   Epratuzumab   D04036   [1] CD22   [3] B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage   [1]
49 
 164   Erl080a   -   -   -   -   [1]
49 
 165   Estradiol   Estradiol   D00105, D01413, D01617, D01953, D04061, D04063, D04064, D04065   [2] ESR1, ESR2   [9] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway   [5]
13,
46,
49,
226,
299 
 166   Ethinyl estradiol   Estradiol   D00105, D01413, D01617, D01953, D04061, D04063, D04064, D04065   [2] ESR1, ESR2   [9] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway   [3]
46,
49,
299 
 167   Ethylhydrogenfumarat, calciumsalz   -   -   -   -   [1]
49 
 168   Ethylhydrogenfumarat, magnesiumsalz   -   -   -   -   [1]
49 
 169   Ethylhydrogenfumarat, zinksalz   -   -   -   -   [1]
49 
 170   Evobrutinib   Evobrutinib   -   -   -   [3]
13,
46,
49 
 171   Extended release dipyridamole 200mg/aspirin 25mg   Dipyridamole   D00302   [2] PDE4A, PDE5A   [6] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
49 
 172   Ezetimibe   Ezetimibe   D01966   [1] NPC1L1   [1] Fat digestion and absorption   [4]
49,
79,
93,
260 
 173   Ezetimibe+simvastatin drug combination   Simvastatin   D00434   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [1]
49 
 174   Filgrastim   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [25]
2,
6,
13,
25,
26,
28,
34,
35,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
96,
113,
164,
283,
284,
285,
331 
 175   Fish oil   Fish oil   -   -   -   [7]
13,
46,
49,
66,
96,
260,
299 
 176   Fludarabine   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [17]
13,
28,
36,
46,
49,
51,
60,
61,
62,
65,
85,
96,
164,
283,
284,
285,
326 
 177   Fludarabine monophosphate   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [4]
49,
65,
284,
326 
 178   Fludarabine phosphate   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [11]
28,
36,
49,
51,
60,
62,
65,
96,
283,
284,
285 
 179   Fluorine f 18   -   -   -   -   [4]
40,
46,
49,
96 
 180   Fluzone   -   -   -   -   [1]
49 
 181   Focetria (monovalent mf59-adjuvanted vaccine)   -   -   -   -   [3]
46,
49,
271 
 182   Folate   Folic acid   D00070   -   -   [3]
13,
46,
49 
 183   Folatescan (technetium tc 99mec20)   -   -   -   -   [4]
13,
46,
49,
96 
 184   Folic acid   Folic acid   D00070   -   -   [4]
6,
46,
49,
84 
 185   Forigerimod   Forigerimod   D09904   -   -   [1]
49 
 186   Fostamatinib   Fostamatinib   D09347   [1] SYK   [15] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis   [4]
46,
49,
61,
66 
 187   Fostamatinib disodium (r935788)   Fostamatinib   D09347   [1] SYK   [15] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis   [2]
46,
49 
 188   Fumaderm   Dimethyl fumarate   D03846   [1] KEAP1   [4] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquitin mediated proteolysis   [1]
49 
 189   Fumaderm®   Dimethyl fumarate   D03846   [1] KEAP1   [4] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquitin mediated proteolysis   [1]
49 
 190   Fumaderm® initial   Dimethyl fumarate   D03846   [1] KEAP1   [4] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquitin mediated proteolysis   [1]
49 
 191   G-csf   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [12]
6,
13,
16,
49,
51,
60,
65,
85,
96,
284,
285,
331 
 192   Gardasil   Human papillomavirus type 6 l1 capsid protein antigen   -   -   -   [1]
49 
 193   Gc+hcq   -   -   -   -   [1]
49 
 194   Gdc-0853   -   -   -   -   [2]
46,
49 
 195   Gdc-0853 (high dose)   -   -   -   -   [1]
49 
 196   Gdc-0853 (low dose)   -   -   -   -   [1]
49 
 197   Gdc-0853 ro7010939   -   -   -   -   [2]
46,
49 
 198   Gl701   -   -   -   -   [1]
49 
 199   Group a sle prospective study   -   -   -   -   [1]
49 
 200   Growth colony stimulating factor (g-csf)   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [1]
49 
 201   Gsk1550188   -   -   -   -   [3]
11,
49,
222 
 202   Gsk1550188 1mg/kg or 10mg/kg   -   -   -   -   [1]
49 
 203   Gsk1550188 iv   -   -   -   -   [1]
49 
 204   Gsk1550188 sc   -   -   -   -   [1]
49 
 205   Gsk2586184   -   -   -   -   [1]
49 
 206   Gsk2586184 100 mg   -   -   -   -   [1]
49 
 207   Gsk2586184 200 mg   -   -   -   -   [1]
49 
 208   Gsk2586184 400 mg   -   -   -   -   [1]
49 
 209   Gsk2586184 50 mg   -   -   -   -   [1]
49 
 210   Gsk2586184 800mg single and repeat dose   -   -   -   -   [1]
49 
 211   Gsk2586184 new formulation   -   -   -   -   [1]
49 
 212   Gsk2586184 standard formulation   -   -   -   -   [1]
49 
 213   H.p. acthar gel   -   -   -   -   [5]
46,
49,
50,
84,
222 
 214   Hematopoietic stem cell transplantation   -   -   -   -   [12]
11,
13,
14,
19,
20,
35,
46,
49,
51,
96,
234,
285 
 215   Hgs1006   -   -   -   -   [1]
49 
 216   Hgs1006, lymphostat-b, monoclonal anti-blys, lsb, benlysta   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [2]
49,
53 
 217   High dietary sodium   -   -   -   -   [1]
49 
 218   High dose mesenchymal stem cells (mscs)   -   -   -   -   [1]
49 
 219   Hiomega-3 supplement of naturalis® company -   -   -   -   -   [1]
49 
 220   Hll2   -   -   -   -   [1]
49 
 221   Hll2 (epratuzumab)   Epratuzumab   D04036   [1] CD22   [3] B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage   [1]
49 
 222   Hll2 (trivial name or chemical description)   -   -   -   -   [1]
49 
 223   Hpv prophylactic vaccine gardasil   -   -   -   -   [1]
49 
 224   Hril-2 active   -   -   -   -   [3]
46,
49,
53 
 225   Human papillomavirus vaccination (gardasil)   -   -   -   -   [1]
49 
 226   Human umbilical cord derived msc transplantation for sle   -   -   -   -   [1]
49 
 227   Hydroxychloroquine   Hydroxychloroquine   D08050   -   -   [18]
13,
41,
46,
48,
49,
53,
56,
66,
84,
89,
90,
96,
222,
234,
254,
271,
298,
299 
 228   Hydroxychloroquine (z0188)   Hydroxychloroquine   D08050   -   -   [1]
49 
 229   Hydroxychloroquine high   Hydroxychloroquine   D08050   -   -   [1]
49 
 230   Hydroxychloroquine or chloroquine   Hydroxychloroquine   D08050   -   -   [1]
49 
 231   Hydroxychloroquine reduced   Hydroxychloroquine   D08050   -   -   [1]
49 
 232   Ianalumab   -   -   -   -   [3]
35,
49,
53 
 233   Ibandronate   Ibandronate   D08056   [1] FDPS   [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis   [2]
46,
49 
 234   Ibandronate+alfacalcidol+calcium   Alfacalcidol   D01518   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [1]
49 
 235   Ici 182,780 (faslodex)   -   -   -   -   [1]
49 
 236   Icp-022   -   -   -   -   [2]
46,
49 
 237   Ifn-a 2b kinoid drug substance   -   -   -   -   [1]
49 
 238   Ifn-a2b kinoid   -   -   -   -   [1]
49 
 239   Ifn-k   -   -   -   -   [2]
49,
50 
 240   Ifn-kinoid   -   -   -   -   [2]
49,
50 
 241   Ifn-kinoid drug substance   -   -   -   -   [2]
49,
50 
 242   Il-2   Human interleukin-2   -   -   -   [5]
2,
46,
49,
56,
96 
 243   Ilt-101   -   -   -   -   [1]
49 
 244   Immu-103   -   -   -   -   [1]
49 
 245   Immune ablation and hematopoietic stem cell support.   -   -   -   -   [1]
49 
 246   Immunoglobulin g   -   -   -   -   [7]
11,
13,
14,
49,
50,
63,
65 
 247   Immunoglobulin g1, anti-(human type i interferon receptor) (human monoclonal medi-546 heavy chain), disulfide with human monoclonal medi-546-chain, dimer   -   -   -   -   [1]
49 
 248   Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate)   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [1]
49 
 249   Individualized dose of rituximab   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [1]
49 
 250   Infliximab   Infliximab   D02598   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [22]
35,
37,
38,
39,
40,
41,
43,
45,
46,
49,
50,
56,
65,
84,
95,
96,
97,
98,
162,
164,
269,
271 
 251   Influenz virus surface antigens   -   -   -   -   [1]
49 
 252   Influenza vaccine (surface antigen, inactivated)   -   -   -   -   [1]
49 
 253   Influvac   -   -   -   -   [3]
46,
49,
50 
 254   Interleukin 2   Human interleukin-2   -   -   -   [9]
46,
49,
51,
56,
63,
95,
96,
97,
271 
 255   Interleukin-2   Human interleukin-2   -   -   -   [6]
2,
35,
49,
55,
65,
97 
 256   Intravenous immunoglobulin   Immune globulin human   -   -   -   [16]
2,
11,
14,
17,
18,
35,
38,
39,
49,
51,
63,
65,
85,
164,
296,
309 
 257   Ipp-201101   -   -   -   -   [1]
49 
 258   Ipp-201101, p140   -   -   -   -   [1]
49 
 259   Iscalimab   Iscalimab   D11610   [1] CD40   [16] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis   [1]
49 
 260   Itolizumab [bmab 600]   -   -   -   -   [1]
49 
 261   Jbt-101   -   -   -   -   [4]
49,
50,
51,
299 
 262   Jnj-55920839   -   -   -   -   [1]
49 
 263   Jnj-56022473   -   -   -   -   [1]
49 
 264   Kineret   Anakinra   D02934   [2] IL1R1, IL1R2   [15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer   [5]
41,
49,
65,
266,
299 
 265   Kpg-818   -   -   -   -   [1]
49 
 266   Kzr-616   -   -   -   -   [3]
49,
50,
61 
 267   L04aa26   -   -   -   -   [1]
49 
 268   Laquinimod   Laquinimod   -   -   -   [4]
8,
13,
49,
96 
 269   Leflunomide   Leflunomide   D00749   [1] DHODH   [2] Metabolic pathways, Pyrimidine metabolism   [9]
11,
40,
46,
49,
53,
66,
224,
271,
300 
 270   Lenalidomide   Lenalidomide   D04687   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [7]
16,
26,
28,
34,
49,
284,
300 
 271   Levothyroxine   Levothyroxine   D01010, D08125   [2] THRA, THRB   [2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway   [2]
49,
78 
 272   Ljp 394   -   -   -   -   [1]
49 
 273   Ljp394   -   -   -   -   [1]
49 
 274   Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol)   Estradiol   D00105, D01413, D01617, D01953, D04061, D04063, D04064, D04065   [2] ESR1, ESR2   [9] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway   [2]
46,
49 
 275   Low dietary sodium   -   -   -   -   [1]
49 
 276   Low dose mesenchymal stem cells (mscs)   -   -   -   -   [1]
49 
 277   Low-dose aldesleukin (proleukin®)   Aldesleukin   D00748   [3] IL2RA, IL2RB, IL2RG   [14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease (IBD), JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor   [1]
49 
 278   Lulizumab pegol   Lulizumab pegol   -   -   -   [1]
49 
 279   Lupuzor   -   -   -   -   [1]
49 
 280   Ly2127399   -   -   -   -   [3]
13,
46,
49 
 281   Ly3009104   -   -   -   -   [4]
46,
49,
50,
325 
 282   Ly3361237   -   -   -   -   [1]
49 
 283   Lymphostat-b tm   -   -   -   -   [1]
49 
 284   M2951   -   -   -   -   [3]
13,
46,
49 
 285   M2951 (other name: evobrutinib)   Evobrutinib   -   -   -   [1]
49 
 286   Mabthera (rituximab)   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [4]
13,
46,
49,
53 
 287   Medi 545   -   -   -   -   [1]
49 
 288   Medi-545   -   -   -   -   [2]
49,
50 
 289   Medi-545 600   -   -   -   -   [1]
49 
 290   Medi-546   -   -   -   -   [1]
49 
 291   Medi-570 0.03 mg   -   -   -   -   [1]
49 
 292   Medi-570 0.1 mg   -   -   -   -   [1]
49 
 293   Medi-570 0.3 mg   -   -   -   -   [1]
49 
 294   Medi-570 1 mg   -   -   -   -   [1]
49 
 295   Medroxyprogesterone   -   -   -   -   [1]
49 
 296   Melatonin   Melatonin   D08170   [2] MTNR1A, MTNR1B   [2] Circadian entrainment, Neuroactive ligand-receptor interaction   [8]
6,
13,
46,
49,
90,
97,
144,
202 
 297   Meloxicam   Meloxicam   D00969   [1] PTGS2   [20] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway   [4]
46,
49,
271,
296 
 298   Memantine   Memantine   D04905, D08174   [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [7]
2,
6,
8,
13,
49,
127,
205 
 299   Mesenchymal stem cells   -   -   -   -   [11]
2,
6,
13,
20,
49,
51,
60,
96,
222,
274,
299 
 300   Mesna   Coenzyme m   -   -   -   [9]
13,
44,
45,
49,
51,
60,
65,
96,
164 
 301   Metformin   Metformin   D00944, D04966   [2] PRKAA1, PRKAA2   [19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway   [16]
6,
13,
46,
49,
67,
75,
77,
81,
86,
113,
158,
206,
225,
233,
265,
285 
 302   Methotrexate   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [33]
11,
13,
19,
34,
35,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
55,
56,
60,
62,
65,
84,
93,
96,
97,
162,
164,
172,
256,
271,
284,
285,
326,
331 
 303   Methotrexate and folic acid   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [1]
49 
 304   Methyl prednisolone   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [3]
43,
49,
96 
 305   Methylprednisolone   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [36]
2,
13,
25,
26,
35,
38,
39,
40,
41,
42,
43,
45,
46,
49,
50,
51,
60,
63,
64,
65,
66,
83,
84,
86,
96,
97,
145,
164,
220,
222,
224,
271,
283,
284,
285,
296 
 306   Micofenolico acido   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [1]
49 
 307   Milatuzumab   Milatuzumab   D08944   [1] CD74   [3] Antigen processing and presentation, Herpes simplex virus 1 infection, Tuberculosis   [1]
49 
 308   Milnacipran   Milnacipran   D08222   [2] SLC6A2, SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [2]
46,
49 
 309   Mizoribine   Mizoribine   D01392   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [7]
49,
51,
53,
66,
94,
222,
224 
 310   Modafinil   Modafinil   D01832   -   -   [4]
6,
13,
49,
93 
 311   Mofetil   -   -   -   -   [1]
49 
 312   Monitor   Methamidophos   -   -   -   [12]
2,
11,
13,
19,
46,
49,
58,
70,
85,
98,
298,
300 
 313   Moxifloxacin   Moxifloxacin   D00874, D08237   -   -   [8]
2,
6,
46,
49,
85,
86,
240,
299 
 314   Mra 003 us   -   -   -   -   [1]
49 
 315   Msc treatment   -   -   -   -   [1]
49 
 316   Msc2364447c   -   -   -   -   [1]
49 
 317   Mt-1303 high dose   -   -   -   -   [1]
49 
 318   Mt-1303 low dose   -   -   -   -   [1]
49 
 319   Mti   Afamelanotide   D10511   -   -   [1]
49 
 320   Multivitamin   Cyanocobalamin   D00166, D03615, D03616, D03617   -   -   [1]
49 
 321   Mycophenolate   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [33]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
84,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 322   Mycophenolate mofetil   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [32]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 323   Mycophenolate mofetil (mmf)   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [4]
49,
60,
66,
222 
 324   Mycophenolate motetil   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [1]
49 
 325   Mycophenolic acid   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [7]
11,
49,
51,
60,
66,
96,
222 
 326   Myfortic   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [4]
49,
66,
222,
228 
 327   N-(5-{4-[(3,3-dimethyl-1-azetidinyl)carbonyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide   -   -   -   -   [1]
49 
 328   N-acetylcysteine   Acetylcysteine   D00221   -   -   [10]
6,
13,
19,
20,
49,
58,
85,
111,
164,
299 
 329   Nelfinavir   Nelfinavir   D00899, D08259   -   -   [3]
49,
265,
331 
 330   Nicotinamide   Nicotinamide   D00036   -   -   [3]
6,
49,
162 
 331   Nivolumab   Nivolumab   D10316   [1] PDCD1   [3] Cell adhesion molecules (CAMs), PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway   [10]
13,
26,
41,
46,
49,
50,
51,
53,
96,
97 
 332   Nktr-358   -   -   -   -   [1]
49 
 333   Nnc 0151-0000-0000   -   -   -   -   [2]
46,
49 
 334   Nnc0114-0006   -   -   -   -   [2]
46,
49 
 335   Norethindrone   Norethisterone   D00182, D00953   [1] PGR   [4] Breast cancer, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation   [4]
13,
46,
49,
299 
 336   Normal saline   -   -   -   -   [14]
6,
17,
22,
36,
46,
49,
60,
94,
96,
211,
226,
276,
296,
299 
 337   Nox-e36   -   -   -   -   [1]
49 
 338   Null   -   -   -   -   [17]
6,
13,
14,
15,
28,
37,
46,
49,
51,
63,
86,
90,
96,
97,
107,
145,
271 
 339   Ocrelizumab   Ocrelizumab   D05218   [1] MS4A1   [1] Hematopoietic cell lineage   [3]
13,
46,
49 
 340   Olive   Olea europaea leaf   -   -   -   [3]
13,
49,
53 
 341   Olive oil   Olive oil   D03311   -   -   [3]
13,
49,
53 
 342   Omacor   Omega-3-acid ethyl esters   D05255   [2] CETP, LPL   [4] Alzheimer disease, Cholesterol metabolism, Glycerolipid metabolism, PPAR signaling pathway   [1]
49 
 343   Omega-3   Omega-3 fatty acids   -   -   -   [7]
13,
46,
49,
66,
79,
96,
299 
 344   Oral prednisolone   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [2]
49,
145 
 345   Oral prednisone 5mg   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
49 
 346   Ortho-novum 777   -   -   -   -   [1]
49 
 347   Oxygen   Oxygen   D00003   -   -   [14]
46,
49,
70,
84,
85,
86,
88,
90,
96,
97,
193,
226,
299,
330 
 348   Ozone   Ozone   -   -   -   [2]
49,
51 
 349   Paquinimod   Paquinimod   -   -   -   [2]
49,
51 
 350   Pf-04236921   -   -   -   -   [2]
49,
96 
 351   Pf-06700841   -   -   -   -   [3]
49,
96,
97 
 352   Pf-06700841 15 mg   -   -   -   -   [1]
49 
 353   Pf-06700841 30 mg   -   -   -   -   [1]
49 
 354   Pf-06700841 45 mg   -   -   -   -   [1]
49 
 355   Pf-06835375   -   -   -   -   [2]
46,
49 
 356   Phosphate   Phosphate ion   -   -   -   [29]
2,
3,
11,
12,
13,
28,
36,
46,
49,
51,
53,
60,
62,
65,
70,
78,
81,
83,
90,
96,
97,
164,
235,
256,
283,
284,
285,
286,
299 
 357   Phosphate-buffered saline   Phosphate ion   -   -   -   [1]
49 
 358   Pioglitazone   Pioglitazone   D00945, D08378   [1] PPARG   [9] AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer   [17]
2,
6,
13,
15,
20,
46,
49,
65,
67,
78,
81,
86,
96,
229,
265,
298,
299 
 359   Pitavastatin   Pitavastatin   D01862   -   -   [1]
49 
 360   Placebo   -   -   -   -   [20]
3,
6,
13,
14,
40,
46,
49,
50,
51,
66,
67,
79,
85,
86,
88,
96,
97,
144,
149,
226 
 361   Plaquenil   Hydroxychloroquine   D08050   -   -   [4]
46,
49,
53,
96 
 362   Pneumovax   -   -   -   -   [3]
46,
49,
96 
 363   Prasterone   Prasterone   D08409   [3] AR, ESR1, ESR2   [11] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway   [1]
49 
 364   Prasterone (gl701)   Prasterone   D08409   [3] AR, ESR1, ESR2   [11] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway   [1]
49 
 365   Pravastatin   Pravastatin   D00893, D08410   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [9]
13,
46,
49,
67,
79,
96,
164,
265,
333 
 366   Prednisolone   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [38]
11,
13,
25,
26,
35,
38,
39,
41,
43,
44,
45,
46,
49,
50,
51,
56,
60,
61,
63,
64,
65,
66,
75,
81,
84,
85,
95,
96,
97,
113,
145,
162,
222,
269,
271,
296,
299,
300 
 367   Prednisona   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [2]
49,
222 
 368   Prednisone   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [43]
2,
11,
13,
14,
26,
35,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
61,
63,
64,
65,
66,
81,
84,
85,
86,
95,
96,
97,
113,
162,
164,
222,
224,
228,
251,
283,
284,
285,
288,
299,
300,
331 
 369   Prednisone acetate   Prednisone acetate   D08416   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [3]
40,
49,
224 
 370   Prednisone discontinuation   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
49 
 371   Premarin and provera   -   -   -   -   [1]
49 
 372   Prevenar® and pneumo23®   -   -   -   -   [1]
49 
 373   Proleukin   Aldesleukin   D00748   [3] IL2RA, IL2RB, IL2RG   [14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease (IBD), JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor   [2]
2,
49 
 374   Quinipril   -   -   -   -   [1]
49 
 375   R-salbutamol   Salbutamol   D02147   [1] ADRB2   [8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
49 
 376   R-salbutamol sulphate   Salbutamol   D02147   [1] ADRB2   [8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
49 
 377   R932333   -   -   -   -   [1]
49 
 378   Rabbit   Rabbit   -   -   -   [7]
13,
49,
51,
60,
65,
96,
285 
 379   Rabbit anti-thymocyte globulin   Rabbit   -   -   -   [2]
49,
65 
 380   Rabbit antithymocyte globulin   Rabbit   -   -   -   [3]
49,
60,
96 
 381   Ramipril   Ramipril   D00421   [1] ACE   [4] Chagas disease (American trypanosomiasis), Hypertrophic cardiomyopathy (HCM), Renin secretion, Renin-angiotensin system   [7]
46,
49,
66,
67,
113,
218,
257 
 382   Rankl/opg ratio   -   -   -   -   [1]
49 
 383   Rapamycin   Sirolimus   D00753   [1] MTOR   [43] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway   [16]
2,
15,
34,
35,
46,
49,
51,
60,
61,
67,
86,
89,
158,
256,
278,
279 
 384   Raptiva   Efalizumab   D03959   [1] ITGAL   [11] Cell adhesion molecules (CAMs), Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis   [3]
37,
49,
53 
 385   Rayos   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
49 
 386   Rc18 160 mg plus standard therapy   -   -   -   -   [1]
49 
 387   Rc18 240 mg plus standard therapy   -   -   -   -   [1]
49 
 388   Rc18 80 mg plus standard therapy   -   -   -   -   [1]
49 
 389   Remicade   Infliximab   D02598   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [8]
46,
49,
56,
84,
85,
96,
97,
271 
 390   Rhumab 2h7   -   -   -   -   [3]
13,
46,
49 
 391   Rhumab ifnalpha   -   -   -   -   [1]
49 
 392   Riquent   -   -   -   -   [1]
49 
 393   Rituxan (rituximab)   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [1]
49 
 394   Rituximab   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [42]
11,
13,
14,
17,
35,
36,
43,
44,
45,
46,
49,
50,
51,
52,
53,
56,
60,
61,
63,
64,
65,
66,
83,
84,
85,
86,
93,
94,
96,
97,
162,
222,
223,
229,
256,
271,
283,
284,
285,
288,
300,
331 
 395   Rivaroxaban   Rivaroxaban   D07086   [1] F10   [1] Complement and coagulation cascades   [2]
46,
49 
 396   Ro 106-1443   -   -   -   -   [1]
49 
 397   Ro 496-4913   -   -   -   -   [2]
46,
49 
 398   Ro7010939/f13   -   -   -   -   [1]
49 
 399   Rontalizumab   Rontalizumab   D09662   [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8   [22] Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis   [1]
49 
 400   Rosuvastatin   Rosuvastatin   D01915, D08492   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [8]
6,
46,
49,
51,
79,
96,
271,
299 
 401   Rosuvastatin calcium   Rosuvastatin   D01915, D08492   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [3]
49,
79,
299 
 402   Royal jelly   Royal jelly   D09754   -   -   [1]
49 
 403   Rslv-132   -   -   -   -   [2]
49,
53 
 404   Salbutamol   Salbutamol   D02147   [1] ADRB2   [8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway   [8]
3,
11,
49,
85,
86,
228,
256,
299 
 405   Same   Ademetionine   D07128   -   -   [15]
6,
14,
22,
43,
44,
46,
47,
49,
50,
60,
84,
93,
96,
97,
172 
 406   Sar113244   -   -   -   -   [1]
49 
 407   Sbi-087   -   -   -   -   [2]
46,
49 
 408   Sc belimumab 200 mg   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [1]
49 
 409   Sifalimumab   Sifalimumab   D09668   [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8   [22] Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis   [1]
49 
 410   Sifalimumab 1,200 mg   Sifalimumab   D09668   [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8   [22] Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis   [1]
49 
 411   Sifalimumab 200 mg   Sifalimumab   D09668   [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8   [22] Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis   [1]
49 
 412   Sifalimumab 600 mg   Sifalimumab   D09668   [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8   [22] Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis   [1]
49 
 413   Simvastatin   Simvastatin   D00434   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [19]
6,
13,
15,
34,
46,
49,
51,
66,
79,
86,
89,
94,
158,
162,
195,
265,
298,
299,
310 
 414   Sm101   -   -   -   -   [3]
49,
63,
66 
 415   Sm934   -   -   -   -   [1]
49 
 416   Sodium-2-mercapto ethane sulphonate   -   -   -   -   [1]
49 
 417   Soluble fc receptor   -   -   -   -   [1]
49 
 418   Soluble fc-gamma receptor iib   -   -   -   -   [1]
49 
 419   Sq fludarabine   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [1]
49 
 420   Standard dose of rituximab   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [1]
49 
 421   Standard of care   -   -   -   -   [8]
6,
13,
14,
49,
51,
64,
79,
85 
 422   Standard therapy   -   -   -   -   [2]
49,
97 
 423   Standard therapy (excluding immunosuppressants)   -   -   -   -   [1]
49 
 424   Standard therapy (including immunosuppressants)   -   -   -   -   [1]
49 
 425   Stelara   Ustekinumab   D09214   [3] IL12A, IL12B, IL23A   [25] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease (IBD), Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus   [3]
49,
96,
269 
 426   Steriod taper   -   -   -   -   [1]
49 
 427   Subcuvia   -   -   -   -   [3]
14,
49,
65 
 428   Sugar pill   -   -   -   -   [7]
6,
49,
67,
70,
86,
206,
226 
 429   Sulfamethoxazole   Sulfamethoxazole   D00447   -   -   [4]
44,
49,
85,
299 
 430   Sulfate   Sulfate ion   -   -   -   [22]
2,
6,
11,
13,
26,
34,
36,
46,
49,
60,
61,
64,
66,
79,
86,
96,
222,
226,
265,
296,
297,
299 
 431   Switch to myfortic   -   -   -   -   [1]
49 
 432   Tab08   -   -   -   -   [2]
46,
49 
 433   Tabalumab   Tabalumab   D10083   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [2]
46,
49 
 434   Tabalumab auto-injector   Tabalumab   D10083   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [2]
46,
49 
 435   Tabalumab prefilled syringe   Tabalumab   D10083   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [2]
46,
49 
 436   Taci-fc5   Atacicept   D09704   [2] TNFSF13, TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [3]
13,
46,
49 
 437   Tacrolimus   Tacrolimus   D00107, D08556   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [29]
2,
11,
13,
36,
46,
49,
50,
51,
53,
60,
61,
62,
65,
66,
85,
95,
96,
97,
113,
151,
158,
164,
222,
224,
226,
228,
283,
284,
299 
 438   Tak-079   -   -   -   -   [1]
49 
 439   Thalidomide   Thalidomide   D00754   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [18]
2,
16,
20,
28,
49,
51,
53,
65,
84,
85,
94,
96,
97,
227,
271,
280,
298,
331 
 440   The generic name is warfarin and many producers will be involved   Warfarin   D00564, D01280, D08682   [2] NQO1, VKORC1   [5] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis   [1]
49 
 441   Tocopherol   Tocopherol   D02332   -   -   [3]
13,
49,
257 
 442   Tocopherol acetate   Tocopherol   D02332   -   -   [1]
49 
 443   Toctino®   -   -   -   -   [1]
49 
 444   Tofacitinib   Tofacitinib   D09970   [4] JAK1, JAK2, JAK3, TYK2   [34] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis   [9]
46,
49,
50,
51,
84,
96,
97,
107,
271 
 445   Tofacitinib citrate   Tofacitinib   D09970   [4] JAK1, JAK2, JAK3, TYK2   [34] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis   [3]
46,
49,
271 
 446   Trade name xarelto   Rivaroxaban   D07086   [1] F10   [1] Complement and coagulation cascades   [1]
49 
 447   Trimethoprim   Trimethoprim   D00145, D06236   -   -   [6]
36,
44,
49,
60,
85,
299 
 448   Trimethoprim-sulfamethoxazole   Sulfamethoxazole   D00447   -   -   [2]
49,
299 
 449   Triptorelin   Triptorelin   D06247   [1] GNRHR   [2] GnRH signaling pathway, Neuroactive ligand-receptor interaction   [2]
49,
76 
 450   Triptorelin pamoate   Triptorelin   D06247   [1] GNRHR   [2] GnRH signaling pathway, Neuroactive ligand-receptor interaction   [1]
49 
 451   Tru-015   -   -   -   -   [3]
46,
49,
222 
 452   Truxima   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [1]
49 
 453   Tv-4710   -   -   -   -   [1]
49 
 454   Upadacitinib   Upadacitinib   D10994   [1] JAK1   [26] EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis   [6]
41,
46,
49,
96,
97,
271 
 455   Urine sample   -   -   -   -   [3]
49,
51,
61 
 456   Ustekinumab   Ustekinumab   D09214   [3] IL12A, IL12B, IL23A   [25] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease (IBD), Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus   [15]
37,
41,
46,
49,
50,
53,
56,
65,
84,
93,
96,
97,
162,
269,
271 
 457   Ustekinumab (approximately 6 mg/kg)   Ustekinumab   D09214   [3] IL12A, IL12B, IL23A   [25] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease (IBD), Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus   [1]
49 
 458   Ustekinumab 90 milligram (mg)   Ustekinumab   D09214   [3] IL12A, IL12B, IL23A   [25] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease (IBD), Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus   [1]
49 
 459   Ustekinumab iv   Ustekinumab   D09214   [3] IL12A, IL12B, IL23A   [25] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease (IBD), Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus   [2]
49,
97 
 460   Ustekinumab sc   Ustekinumab   D09214   [3] IL12A, IL12B, IL23A   [25] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease (IBD), Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus   [2]
49,
97 
 461   Vaccination   -   -   -   -   [1]
49 
 462   Vaccine   -   -   -   -   [1]
49 
 463   Vay736   -   -   -   -   [7]
13,
35,
46,
49,
53,
85,
95 
 464   Velcade®   Bortezomib   D03150   [1] PSMB5   [1] Proteasome   [3]
11,
46,
49 
 465   Versus hydroxychloroquine   Hydroxychloroquine   D08050   -   -   [1]
49 
 466   Vib7734   -   -   -   -   [4]
49,
50,
51,
53 
 467   Vitamin d   Vitamin d   -   -   -   [18]
13,
19,
41,
46,
49,
50,
68,
93,
95,
96,
98,
179,
222,
228,
235,
274,
298,
299 
 468   Vitamin d 25(oh)d   Vitamin d   -   -   -   [1]
49 
 469   Vitamin d3   Cholecalciferol   D00188   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [11]
6,
13,
20,
46,
49,
53,
60,
65,
96,
97,
299 
 470   Vitamin d3 400 iu   Cholecalciferol   D00188   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [1]
49 
 471   Vitamin d3 6000 iu   Cholecalciferol   D00188   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [1]
49 
 472   Vitamins: b6, b12, and folate   Folic acid   D00070   -   -   [1]
49 
 473   Warfarin   Warfarin   D00564, D01280, D08682   [2] NQO1, VKORC1   [5] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis   [10]
6,
8,
13,
19,
46,
49,
66,
85,
88,
96 
 474   Xarelto   Rivaroxaban   D07086   [1] F10   [1] Complement and coagulation cascades   [1]
49 
 475   Xmab5871   -   -   -   -   [2]
49,
300 
 476   Zostavax   -   -   -   -   [1]
49 
 477   Zostavax vaccine   -   -   -   -   [2]
46,
49 

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