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   e.g. "Sirolimus", "Adalimumab"

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287 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG *   KEGG GENES * 
 [Number of genes] 		  KEGG PATHWAY 
 [Number of pathways] 		  Disease ID * 
 [Number of diseases] 
 1   0.9% sodium chloride   Sodium chloride   D02056   -   -   [3]
6,
14,
51 
 2   1-(6-benzothiazolylsulfonyl)-5-chloro-1h-indole-2-butanoic acid   Indole   -   -   -   [1]
51 
 3   1-22460   -   -   -   -   [1]
51 
 4   Abatacept   Abatacept   D03203   [2] CD80, CD86   [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis   [24]
11,
13,
19,
41,
44,
46,
49,
50,
51,
53,
55,
60,
65,
84,
93,
96,
97,
107,
164,
222,
271,
284,
285,
300 
 5   Abituzumab   Abituzumab   -   -   -   [1]
51 
 6   Abituzumab 1500 mg   Abituzumab   -   -   -   [1]
51 
 7   Abituzumab 500 mg   Abituzumab   -   -   -   [1]
51 
 8   Abr-215757   -   -   -   -   [2]
49,
51 
 9   Acetaminophen   Acetaminophen   D00217   [2] PTGS1, PTGS2   [21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway   [11]
13,
34,
35,
46,
49,
51,
70,
86,
231,
256,
271 
 10   Acetate   Acetate   -   -   -   [40]
1,
2,
6,
10,
13,
35,
40,
46,
49,
51,
60,
64,
70,
71,
73,
75,
76,
78,
81,
83,
85,
86,
88,
90,
96,
97,
113,
145,
156,
162,
171,
206,
222,
224,
225,
235,
265,
288,
298,
299 
 11   Acetylcysteine   Acetylcysteine   D00221   -   -   [14]
6,
13,
19,
20,
49,
51,
58,
85,
94,
111,
164,
233,
298,
299 
 12   Acetylsalicylic acid   Acetylsalicylic acid   D00109   [2] PTGS1, PTGS2   [21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway   [3]
13,
46,
51 
 13   Acotiamide   Acotiamide   -   -   -   [1]
51 
 14   Act-293987   -   -   -   -   [2]
51,
86 
 15   Adempas   Riociguat   D09572   [3] GUCY1A1, GUCY1A2, GUCY1B1   [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [4]
51,
86,
225,
299 
 16   Administration of rituximab and methylprednisolone   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
51 
 17   Aimspro   -   -   -   -   [2]
13,
51 
 18   Ajulemic acid   Ajulemic acid   D11312   [1] CNR2   [1] Neuroactive ligand-receptor interaction   [3]
50,
51,
299 
 19   Albumin   -   -   -   -   [2]
2,
51 
 20   Alemtuzumab   Alemtuzumab   D02802   -   -   [13]
13,
15,
19,
20,
46,
51,
60,
63,
65,
85,
96,
164,
284 
 21   Alginic acid   Alginic acid   D02324   -   -   [1]
51 
 22   Allogeneic mesenchymal stem cells (allomsc)   -   -   -   -   [2]
51,
53 
 23   Alpha-2c ar antagonist   -   -   -   -   [1]
51 
 24   Alprostadil   Alprostadil   D00180, D02705   [1] PTGER1   [4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer   [2]
51,
70 
 25   Am-01   -   -   -   -   [1]
51 
 26   Ambrisentan   Ambrisentan   D07077   [1] EDNRA   [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [6]
51,
84,
85,
86,
88,
211 
 27   Amlodipine   Amlodipine   D00615, D02914, D07450   [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   [34] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [4]
51,
65,
67,
298 
 28   Amlodipine gel   Amlodipine   D00615, D02914, D07450   [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   [34] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
51 
 29   Anaerobically cultivated human intestinal microbiota   -   -   -   -   [1]
51 
 30   Anaerobically cultivated medium   -   -   -   -   [1]
51 
 31   Anti-human t-lymphocyte immunoglobulin from rabbits   -   -   -   -   [1]
51 
 32   Anti-pandemic h1n1 influenza vaccine   -   -   -   -   [5]
46,
49,
50,
51,
53 
 33   Anti-thymocyte globulin   -   -   -   -   [18]
11,
13,
14,
36,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
164,
283,
284,
285 
 34   Anti-thymocyte globulin, rabbit   Rabbit   -   -   -   [1]
51 
 35   Asasantin retard   -   -   -   -   [1]
51 
 36   Asasantin retard ®   -   -   -   -   [1]
51 
 37   Aspirin   Acetylsalicylic acid   D00109   [2] PTGS1, PTGS2   [21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway   [10]
13,
22,
34,
46,
49,
51,
86,
113,
158,
231 
 38   Atorvastatin   Atorvastatin   D00258, D00887, D07474   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [17]
13,
46,
49,
51,
58,
63,
79,
84,
88,
93,
96,
160,
222,
225,
265,
271,
299 
 39   Autologous stem cells   -   -   -   -   [2]
13,
51 
 40   Autologous stemcell transplantation with cd (cluster of differentiation) 34 selected stem cells   -   -   -   -   [1]
51 
 41   Avid200   -   -   -   -   [1]
51 
 42   Aviptadil   Aviptadil   -   -   -   [4]
49,
51,
85,
86 
 43   Bay63-2521   -   -   -   -   [3]
51,
86,
299 
 44   Belimumab   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [8]
11,
43,
44,
46,
49,
51,
53,
222 
 45   Bibf 1120   -   -   -   -   [2]
51,
85 
 46   Biopsy   -   -   -   -   [2]
19,
51 
 47   Blood sample   -   -   -   -   [12]
8,
13,
46,
49,
51,
53,
61,
66,
97,
274,
288,
299 
 48   Blood samples   -   -   -   -   [8]
13,
41,
46,
51,
61,
97,
227,
271 
 49   Blood sampling   -   -   -   -   [4]
13,
19,
51,
96 
 50   Bms-986020   -   -   -   -   [2]
51,
85 
 51   Bortezomib   Bortezomib   D03150   [1] PSMB5   [1] Proteasome   [13]
11,
26,
28,
46,
49,
51,
61,
63,
66,
228,
256,
288,
331 
 52   Bosentan   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [9]
13,
41,
47,
51,
84,
85,
86,
88,
210 
 53   Bosentan (tracleer)   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
51 
 54   Bosentan 125 mg   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
51 
 55   Bosentan 62.5 mg   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
51 
 56   Bosentan group   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
51 
 57   Bosentan monohydrate   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [4]
51,
84,
86,
88 
 58   Botox® solution   -   -   -   -   [1]
51 
 59   Botulinum toxin a   Botulinum toxin type a   D00783   [1] SNAP25   [2] Insulin secretion, Synaptic vesicle cycle   [4]
13,
51,
149,
226 
 60   Botulinum toxin type b   Botulinum toxin type b   D02735   [1] SNAP25   [2] Insulin secretion, Synaptic vesicle cycle   [3]
2,
6,
51 
 61   Botulinum toxin type b (2500 units / vial)   Botulinum toxin type b   D02735   [1] SNAP25   [2] Insulin secretion, Synaptic vesicle cycle   [1]
51 
 62   Brentuximab vedotin   Brentuximab vedotin   D09587   [10] TNFRSF8, TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8   [4] Cytokine-cytokine receptor interaction, Gap junction, Pathogenic Escherichia coli infection, Phagosome   [2]
49,
51 
 63   Brodalumab   Brodalumab   D10061   [1] IL17RA   [2] Cytokine-cytokine receptor interaction, IL-17 signaling pathway   [2]
37,
51 
 64   Buspirone   Buspirone   D00702, D07593   [2] DRD2, HTR1A   [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway   [2]
6,
51 
 65   Busulfan   Busulfan   D00248   -   -   [13]
19,
20,
28,
36,
49,
51,
60,
65,
164,
274,
284,
285,
326 
 66   Butanoic acid   Butyric acid   D05866   -   -   [3]
34,
51,
97 
 67   C-82 topical gel, 1%   -   -   -   -   [1]
51 
 68   C225   Cetuximab   D03455   [1] EGFR   [45] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis   [2]
51,
86 
 69   Calcium   Calcium   -   -   -   [24]
6,
13,
19,
46,
49,
51,
65,
68,
75,
79,
84,
93,
94,
95,
96,
97,
214,
215,
222,
224,
235,
265,
298,
299 
 70   Calcium channel blockers   Calcium   -   -   -   [1]
51 
 71   Campath   Alemtuzumab   D02802   -   -   [4]
49,
51,
60,
65 
 72   Capillarema   -   -   -   -   [1]
51 
 73   Cd34 selected autologous hematopoietic cells   -   -   -   -   [1]
51 
 74   Cd34+sc   -   -   -   -   [1]
51 
 75   Cetuximab   Cetuximab   D03455   [1] EGFR   [45] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis   [5]
34,
51,
86,
89,
331 
 76   Chloride   Chloride ion   -   -   -   [17]
6,
11,
13,
14,
34,
46,
51,
96,
97,
127,
168,
193,
227,
228,
288,
297,
299 
 77   Cialis   Tadalafil   D02008   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [2]
51,
86 
 78   Cilostazol   Cilostazol   D01896   [3] PDE3A, PDE3B, TBXA2R   [14] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway   [2]
51,
70 
 79   Coagulation factor xiii   Factor xiii (human)   -   -   -   [1]
51 
 80   Cyclophosphamide   Cyclophosphamide   D00287, D07760   -   -   [43]
13,
14,
16,
19,
20,
26,
28,
35,
36,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
52,
56,
60,
61,
62,
65,
66,
84,
85,
93,
96,
162,
164,
172,
222,
224,
265,
274,
283,
284,
285,
288,
326,
331 
 81   Depot leuprolide acetate 3.75 mg   Leuprolide   D00989, D08113   [1] GNRHR   [2] GnRH signaling pathway, Neuroactive ligand-receptor interaction   [1]
51 
 82   Digna p144 cream   -   -   -   -   [1]
51 
 83   Dimethyl fumarate   Dimethyl fumarate   D03846   [1] KEAP1   [4] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquitin mediated proteolysis   [3]
13,
51,
86 
 84   Dimethyl fumarate (dmf)   Dimethyl fumarate   D03846   [1] KEAP1   [4] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquitin mediated proteolysis   [3]
13,
51,
86 
 85   Diphenhydramine   Diphenhydramine   D00300, D00669, D02419, D03285, D03360, D03854   [1] HRH1   [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction   [5]
49,
51,
70,
86,
256 
 86   Dipyridamole   Dipyridamole   D00302   [2] PDE4A, PDE5A   [6] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway   [5]
46,
49,
51,
66,
224 
 87   Divalproex sodium   -   -   -   -   [1]
51 
 88   Domperidone   Domperidone   D01745, D07868   [1] DRD2   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [5]
6,
13,
17,
51,
230 
 89   Drug treatment   -   -   -   -   [3]
51,
74,
271 
 90   Ema/chmp/212874/2015   -   -   -   -   [1]
51 
 91   Endoprost   -   -   -   -   [1]
51 
 92   Endoprost - 0.05 mg/0.5 ml concentrato per soluzione per infusione 1 fiala   -   -   -   -   [1]
51 
 93   Endoprost 50*infus 1f 0,050mg/   -   -   -   -   [1]
51 
 94   Endothelin receptor blocker   -   -   -   -   [1]
51 
 95   Erbitux   Cetuximab   D03455   [1] EGFR   [45] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis   [2]
51,
86 
 96   Esbriet   Pirfenidone   D01583   [6] CCL2, IL10, IL1A, IL1B, IL6, TNF   [80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [3]
51,
85,
228 
 97   Ex vivo cultured human mesenchymal stem cells   -   -   -   -   [1]
51 
 98   Fibrogammin   Fibrinolysin   D07422   -   -   [2]
51,
288 
 99   Fibrogammin®p, coagulation factor xiii concentrate (human)   Factor xiii (human), Factor xiii (human)   -   -   -   [1]
51 
 100   Filgrastim   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [25]
2,
6,
13,
25,
26,
28,
34,
35,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
96,
113,
164,
283,
284,
285,
331 
 101   Fludarabine   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [17]
13,
28,
36,
46,
49,
51,
60,
61,
62,
65,
85,
96,
164,
283,
284,
285,
326 
 102   Fludarabine phosphate   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [11]
28,
36,
49,
51,
60,
62,
65,
96,
283,
284,
285 
 103   Fresolimumab   Fresolimumab   D09620   [3] TGFB1, TGFB2, TGFB3   [34] AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease (American trypanosomiasis), Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy (HCM), Inflammatory bowel disease (IBD), Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis   [3]
51,
222,
274 
 104   G-csf   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [12]
6,
13,
16,
49,
51,
60,
65,
85,
96,
284,
285,
331 
 105   Glivec   Imatinib   D01441, D08066   [3] ABL1, KIT, PDGFRA   [32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [2]
51,
86 
 106   Glpg1690   -   -   -   -   [2]
51,
85 
 107   Glycyrrhizin   Glycyrrhizic acid   D00157   -   -   [1]
51 
 108   Gm-csf   Regramostim   D05712   [1] CSF2RA   [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer   [4]
11,
46,
51,
229 
 109   Gsk2330811   -   -   -   -   [2]
51,
96 
 110   Gsk2330811 solution for injection, 100mg/ml   -   -   -   -   [1]
51 
 111   Hematopoietic stem cell transplantation   -   -   -   -   [12]
11,
13,
14,
19,
20,
35,
46,
49,
51,
96,
234,
285 
 112   Hidonac*ev 1fl 5g 25ml   -   -   -   -   [1]
51 
 113   High-dose intravenous immunoglobulin (venoglobulin-ih)   Immune globulin human   -   -   -   [1]
51 
 114   Human anti-transforming growth factor beta-1 monoclonal antibody   -   -   -   -   [1]
51 
 115   Hyperimmune caprine serum   -   -   -   -   [1]
51 
 116   Ifetroban   Ifetroban   D04500   [1] TBXA2R   [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation   [3]
51,
86,
113 
 117   Igpro10   -   -   -   -   [3]
14,
51,
65 
 118   Igpro20   -   -   -   -   [3]
14,
51,
65 
 119   Ilomedin   -   -   -   -   [1]
51 
 120   Iloprost   Iloprost   D02721   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [4]
51,
84,
85,
86 
 121   Iloprost injection, for intravenous use   Iloprost   D02721   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [1]
51 
 122   Iloprost low dose   Iloprost   D02721   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [1]
51 
 123   Iloprost sale di trometamolo   Iloprost   D02721   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [1]
51 
 124   Iloprost therapy up to 2 ng/kg x min   Iloprost   D02721   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [1]
51 
 125   Iloprost trometamol   Iloprost   D02721   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [1]
51 
 126   Imatinib   Imatinib   D01441, D08066   [3] ABL1, KIT, PDGFRA   [32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [11]
13,
28,
34,
35,
46,
51,
85,
86,
87,
89,
162 
 127   Imatinib mesylate   Imatinib   D01441, D08066   [3] ABL1, KIT, PDGFRA   [32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [5]
13,
28,
34,
51,
86 
 128   Imnovid 1 mg hard capsules   Pomalidomide   D08976   [2] IL6, TNF   [76] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [1]
51 
 129   Indocyanine green   -   -   -   -   [4]
46,
51,
235,
291 
 130   Indole   Indole   -   -   -   [1]
51 
 131   Injection of allogeneic mesenchymal stem cells   -   -   -   -   [1]
51 
 132   Injection of autologous stromal vascular fraction   -   -   -   -   [1]
51 
 133   Interleukin 2   Human interleukin-2   -   -   -   [9]
46,
49,
51,
56,
63,
95,
96,
97,
271 
 134   Intravenous immunoglobulin   Immune globulin human   -   -   -   [16]
2,
11,
14,
17,
18,
35,
38,
39,
49,
51,
63,
65,
85,
164,
296,
309 
 135   Iontophoresis of treprostinil   Treprostinil   D06213   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [1]
51 
 136   Iv cyclophosphamide   Cyclophosphamide   D00287, D07760   -   -   [1]
51 
 137   Iva337   -   -   -   -   [1]
51 
 138   Ivig   Immune globulin human   -   -   -   [12]
11,
13,
14,
17,
18,
50,
51,
63,
65,
85,
164,
296 
 139   Jbt-101   -   -   -   -   [4]
49,
50,
51,
299 
 140   Kd025   -   -   -   -   [2]
51,
85 
 141   Khk4827   -   -   -   -   [2]
37,
51 
 142   Lactate   Lactic acid   D00111   -   -   [1]
51 
 143   Lactobacillus   -   -   -   -   [1]
51 
 144   Lenabasum   -   -   -   -   [3]
50,
51,
299 
 145   Lenabasum 20 mg   -   -   -   -   [3]
50,
51,
299 
 146   Lenabasum 20 mg powder in capsule   -   -   -   -   [1]
51 
 147   Lenabasum 5 mg   -   -   -   -   [3]
50,
51,
299 
 148   Lenabasum 5 mg powder in capsule   -   -   -   -   [1]
51 
 149   Leuprolide   Leuprolide   D00989, D08113   [1] GNRHR   [2] GnRH signaling pathway, Neuroactive ligand-receptor interaction   [5]
1,
2,
3,
51,
76 
 150   Lipitor   Atorvastatin   D00258, D00887, D07474   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [1]
51 
 151   Mabthera   -   -   -   -   [15]
11,
13,
35,
46,
50,
51,
53,
61,
63,
64,
65,
83,
162,
222,
271 
 152   Macitentan   Macitentan   D10135   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [5]
51,
85,
86,
88,
210 
 153   Mesenchymal stem cells   -   -   -   -   [11]
2,
6,
13,
20,
49,
51,
60,
96,
222,
274,
299 
 154   Mesenchymal stromal cells   -   -   -   -   [6]
36,
51,
96,
97,
274,
284 
 155   Mesna   Coenzyme m   -   -   -   [9]
13,
44,
45,
49,
51,
60,
65,
96,
164 
 156   Methotrexate   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [33]
11,
13,
19,
34,
35,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
55,
56,
60,
62,
65,
84,
93,
96,
97,
162,
164,
172,
256,
271,
284,
285,
326,
331 
 157   Methylprednisolon   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [4]
13,
51,
66,
222 
 158   Methylprednisolone   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [36]
2,
13,
25,
26,
35,
38,
39,
40,
41,
42,
43,
45,
46,
49,
50,
51,
60,
63,
64,
65,
66,
83,
84,
86,
96,
97,
145,
164,
220,
222,
224,
271,
283,
284,
285,
296 
 159   Methylprednisolone sodium succinate   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [3]
13,
46,
51 
 160   Metronidazole   Metronidazole   D00409, D05016, D05017   -   -   [8]
46,
51,
63,
94,
95,
96,
97,
291 
 161   Mhsct   -   -   -   -   [1]
51 
 162   Microgynon   -   -   -   -   [2]
13,
51 
 163   Mizoribine   Mizoribine   D01392   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [7]
49,
51,
53,
66,
94,
222,
224 
 164   Mycophenolate   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [33]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
84,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 165   Mycophenolate mofetil   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [32]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 166   Mycophenolic acid   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [7]
11,
49,
51,
60,
66,
96,
222 
 167   N-acetylcysteine (nac)   Acetylcysteine   D00221   -   -   [2]
51,
299 
 168   Neovasculgen   -   -   -   -   [1]
51 
 169   Neupogen   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [4]
13,
28,
51,
285 
 170   Nilotinib   Nilotinib   D08953   [4] ABL1, KIT, PDGFRA, PDGFRB   [33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [5]
6,
8,
34,
51,
86 
 171   Nilotinib (tasigna)   Nilotinib   D08953   [4] ABL1, KIT, PDGFRA, PDGFRB   [33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [1]
51 
 172   Nintedanib   Nintedanib   D10481   [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB   [34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway   [4]
51,
85,
89,
228 
 173   Nivolumab   Nivolumab   D10316   [1] PDCD1   [3] Cell adhesion molecules (CAMs), PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway   [10]
13,
26,
41,
46,
49,
50,
51,
53,
96,
97 
 174   Null   -   -   -   -   [17]
6,
13,
14,
15,
28,
37,
46,
49,
51,
63,
86,
90,
96,
97,
107,
145,
271 
 175   Ofev   Nintedanib   D10481   [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB   [34] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway   [4]
51,
85,
89,
228 
 176   Omeprazole   Omeprazole   D00455, D01207, D05259, D05261   [2] ATP4A, ATP4B   [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation   [15]
6,
8,
13,
46,
51,
85,
96,
97,
98,
225,
271,
282,
294,
298,
299 
 177   Omeprazole 20mg   Omeprazole   D00455, D01207, D05259, D05261   [2] ATP4A, ATP4B   [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation   [1]
51 
 178   Oral ifetroban   Ifetroban   D04500   [1] TBXA2R   [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation   [2]
51,
86 
 179   Oral treprostinil   Treprostinil   D06213   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [2]
51,
86 
 180   Orencia   Abatacept   D03203   [2] CD80, CD86   [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis   [9]
46,
50,
51,
53,
65,
84,
96,
97,
271 
 181   Orm-12471   -   -   -   -   [1]
51 
 182   Orm-12471 30mg   -   -   -   -   [1]
51 
 183   Orm-12741   -   -   -   -   [1]
51 
 184   Other vasodilator   -   -   -   -   [1]
51 
 185   Ozone   Ozone   -   -   -   [2]
49,
51 
 186   P144   -   -   -   -   [1]
51 
 187   P144. cytokines inhibitors   -   -   -   -   [1]
51 
 188   Paquinimod   Paquinimod   -   -   -   [2]
49,
51 
 189   Part b open-label extension   -   -   -   -   [1]
51 
 190   Peripheral blood stem cells   -   -   -   -   [1]
51 
 191   Phosphate   Phosphate ion   -   -   -   [29]
2,
3,
11,
12,
13,
28,
36,
46,
49,
51,
53,
60,
62,
65,
70,
78,
81,
83,
90,
96,
97,
164,
235,
256,
283,
284,
285,
286,
299 
 192   Phosphodiesterase inhibitors   -   -   -   -   [1]
51 
 193   Physiological saline   -   -   -   -   [1]
51 
 194   Pirfenidone   Pirfenidone   D01583   [6] CCL2, IL10, IL1A, IL1B, IL6, TNF   [80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [10]
34,
46,
50,
51,
58,
84,
85,
164,
222,
228 
 195   Placebo   -   -   -   -   [20]
3,
6,
13,
14,
40,
46,
49,
50,
51,
66,
67,
79,
85,
86,
88,
96,
97,
144,
149,
226 
 196   Platelet gel   -   -   -   -   [1]
51 
 197   Plerixafor   Plerixafor   D08971   [1] CXCR4   [12] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral protein interaction with cytokine and cytokine receptor   [4]
51,
65,
285,
299 
 198   Pletal   Cilostazol   D01896   [3] PDE3A, PDE3B, TBXA2R   [14] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
51 
 199   Pomalidomide   Pomalidomide   D08976   [2] IL6, TNF   [76] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [6]
28,
34,
51,
85,
227,
331 
 200   Prednisolone   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [38]
11,
13,
25,
26,
35,
38,
39,
41,
43,
44,
45,
46,
49,
50,
51,
56,
60,
61,
63,
64,
65,
66,
75,
81,
84,
85,
95,
96,
97,
113,
145,
162,
222,
269,
271,
296,
299,
300 
 201   Prednisolone 5 mg   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [2]
46,
51 
 202   Prednisolone and taper   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
51 
 203   Prednisone   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [43]
2,
11,
13,
14,
26,
35,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
61,
63,
64,
65,
66,
81,
84,
85,
86,
95,
96,
97,
113,
162,
164,
222,
224,
228,
251,
283,
284,
285,
288,
299,
300,
331 
 204   Privigen   Immune globulin human   -   -   -   [4]
11,
14,
51,
65 
 205   Prostanoids   -   -   -   -   [1]
51 
 206   Prucalopride   Prucalopride   D09205   [1] HTR4   [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, cAMP signaling pathway   [3]
13,
51,
96 
 207   Prucalopride succinate   Prucalopride   D09205   [1] HTR4   [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, cAMP signaling pathway   [1]
51 
 208   Qax576   -   -   -   -   [4]
51,
85,
96,
98 
 209   Rabbit   Rabbit   -   -   -   [7]
13,
49,
51,
60,
65,
96,
285 
 210   Rabeprazole   Rabeprazole   D00724, D08463   [2] ATP4A, ATP4B   [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation   [2]
2,
51 
 211   Rapamycin   Sirolimus   D00753   [1] MTOR   [43] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway   [16]
2,
15,
34,
35,
46,
49,
51,
60,
61,
67,
86,
89,
158,
256,
278,
279 
 212   Ratg   -   -   -   -   [2]
13,
51 
 213   Rbatg   -   -   -   -   [2]
51,
96 
 214   Recombinant humanized anti-human monoclonal antibody directed against the il-6r   -   -   -   -   [2]
46,
51 
 215   Relaxin   -   -   -   -   [1]
51 
 216   Resolor*28cpr riv 2mg   -   -   -   -   [1]
51 
 217   Resunab, ajulemic acid, anabasum   Ajulemic acid   D11312   [1] CNR2   [1] Neuroactive ligand-receptor interaction   [3]
50,
51,
299 
 218   Rilonacept   Rilonacept   D06635   [2] IL1A, IL1B   [41] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Prion diseases, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection   [4]
51,
106,
107,
266 
 219   Ringer lactate   Lactic acid   D00111   -   -   [1]
51 
 220   Riociguat   Riociguat   D09572   [3] GUCY1A1, GUCY1A2, GUCY1B1   [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [6]
51,
84,
86,
88,
225,
299 
 221   Riociguat (adempas, bay63-2521)   Riociguat   D09572   [3] GUCY1A1, GUCY1A2, GUCY1B1   [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [3]
51,
86,
88 
 222   Riociguat coated tablet 0.5 mg   Riociguat   D09572   [3] GUCY1A1, GUCY1A2, GUCY1B1   [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
51 
 223   Riociguat coated tablet 1.0 mg   Riociguat   D09572   [3] GUCY1A1, GUCY1A2, GUCY1B1   [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
51 
 224   Riociguat coated tablet 1.5 mg   Riociguat   D09572   [3] GUCY1A1, GUCY1A2, GUCY1B1   [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
51 
 225   Riociguat coated tablet 2.0 mg   Riociguat   D09572   [3] GUCY1A1, GUCY1A2, GUCY1B1   [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
51 
 226   Riociguat coated tablet 2.5 mg   Riociguat   D09572   [3] GUCY1A1, GUCY1A2, GUCY1B1   [11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
51 
 227   Rituximab   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [42]
11,
13,
14,
17,
35,
36,
43,
44,
45,
46,
49,
50,
51,
52,
53,
56,
60,
61,
63,
64,
65,
66,
83,
84,
85,
86,
93,
94,
96,
97,
162,
222,
223,
229,
256,
271,
283,
284,
285,
288,
300,
331 
 228   Ro 47-0203   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [4]
51,
85,
86,
88 
 229   Ro 487-7533/f10-04   -   -   -   -   [4]
41,
46,
51,
107 
 230   Ro47-0203 / act-050088   -   -   -   -   [2]
51,
86 
 231   Ro487-7533/f10-04   -   -   -   -   [2]
46,
51 
 232   Roactemra   -   -   -   -   [5]
41,
46,
51,
86,
107 
 233   Roactemra 162 mg   -   -   -   -   [2]
46,
51 
 234   Rosemary   Rosemary   -   -   -   [1]
51 
 235   Rosuvastatin   Rosuvastatin   D01915, D08492   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [8]
6,
46,
49,
51,
79,
96,
271,
299 
 236   Saccharomyces boulardii oral tablet   -   -   -   -   [1]
51 
 237   Sar100842   -   -   -   -   [1]
51 
 238   Sar156597   -   -   -   -   [2]
51,
85 
 239   Sar156597 (act14604)   -   -   -   -   [1]
51 
 240   Selexipag   Selexipag   D09994   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [5]
51,
70,
84,
86,
88 
 241   Sildenafil   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [15]
6,
46,
50,
51,
85,
86,
113,
210,
211,
212,
225,
226,
278,
294,
299 
 242   Sildenafil 20mg   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [2]
51,
86 
 243   Sildenafil 20mg and bosentan 62.5mg   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [2]
51,
86 
 244   Sildenafil citrate   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [4]
51,
85,
86,
225 
 245   Sildenafil therapy   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [1]
51 
 246   Simvastatin   Simvastatin   D00434   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [19]
6,
13,
15,
34,
46,
49,
51,
66,
79,
86,
89,
94,
158,
162,
195,
265,
298,
299,
310 
 247   Sinvacor*28cpr riv 20mg   -   -   -   -   [1]
51 
 248   Sirolimus   Sirolimus   D00753   [1] MTOR   [43] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway   [30]
13,
17,
34,
35,
36,
46,
51,
60,
62,
63,
65,
66,
67,
85,
89,
96,
98,
137,
157,
158,
192,
222,
277,
278,
279,
280,
281,
283,
285,
331 
 249   Sodium chloride   Sodium chloride   D02056   -   -   [13]
6,
11,
13,
14,
34,
46,
51,
168,
193,
227,
228,
288,
299 
 250   Sodium fluoride   Sodium fluoride   D00943   -   -   [1]
51 
 251   Sodium fluoride 18f   Sodium fluoride   D00943   -   -   [1]
51 
 252   Solu-medrone   -   -   -   -   [3]
51,
83,
162 
 253   Soluble ve cadherin   -   -   -   -   [1]
51 
 254   Standard of care   -   -   -   -   [8]
6,
13,
14,
49,
51,
64,
79,
85 
 255   Steroids   -   -   -   -   [7]
46,
50,
51,
63,
66,
96,
97 
 256   Sti571   Imatinib   D01441, D08066   [3] ABL1, KIT, PDGFRA   [32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [2]
51,
86 
 257   Stromal vascular fraction   -   -   -   -   [1]
51 
 258   Study of the gene expression profile   -   -   -   -   [1]
51 
 259   Tacrolimus   Tacrolimus   D00107, D08556   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [29]
2,
11,
13,
36,
46,
49,
50,
51,
53,
60,
61,
62,
65,
66,
85,
95,
96,
97,
113,
151,
158,
164,
222,
224,
226,
228,
283,
284,
299 
 260   Tadalafil   Tadalafil   D02008   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [6]
6,
51,
75,
84,
86,
113 
 261   Tadalafil and ambrisentan upfront combination therapy   Ambrisentan   D07077   [1] EDNRA   [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [2]
51,
86 
 262   Terguride   Terguride   D01348   [2] DRD2, PRL   [12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway   [2]
51,
86 
 263   Terguride hydrogenmaleate   Terguride   D01348   [2] DRD2, PRL   [12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway   [1]
51 
 264   Thalidomide   Thalidomide   D00754   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [18]
2,
16,
20,
28,
49,
51,
53,
65,
84,
85,
94,
96,
97,
227,
271,
280,
298,
331 
 265   Thiotepa   Thiotepa   D00583   -   -   [11]
13,
19,
20,
28,
51,
60,
65,
85,
96,
164,
284 
 266   Thymoglobulin   -   -   -   -   [4]
36,
51,
60,
96 
 267   Thymoglobuline   -   -   -   -   [4]
13,
36,
51,
65 
 268   Tocilizumab   Tocilizumab   D02596   [1] IL6R   [11] Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease (NAFLD), PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor   [16]
2,
13,
40,
41,
43,
46,
50,
51,
53,
54,
55,
86,
107,
266,
271,
331 
 269   Tocilizumab sc 162 mg/0.9 ml prefilled syringe with safety device (pfs)   Tocilizumab   D02596   [1] IL6R   [11] Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease (NAFLD), PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor   [1]
51 
 270   Tofacitinib   Tofacitinib   D09970   [4] JAK1, JAK2, JAK3, TYK2   [34] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis   [9]
46,
49,
50,
51,
84,
96,
97,
107,
271 
 271   Tracleer   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [8]
13,
51,
84,
85,
86,
88,
210,
211 
 272   Tracleer*125mg 56cpr riv.   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
51 
 273   Tracleer*56cpr riv 125mg   Bosentan   D01227, D07538   [2] EDNRA, EDNRB   [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
51 
 274   Transdihydrolisuride   -   -   -   -   [2]
51,
86 
 275   Treprostinil   Treprostinil   D06213   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [5]
51,
84,
85,
86,
88 
 276   Treprostinil diethanolamine   Treprostinil   D06213   [1] PTGIR   [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction   [2]
51,
86 
 277   Trimebutine   Trimebutine   D08639   [2] OPRK1, OPRM1   [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction   [1]
51 
 278   Trometamol   Tromethamine   D00396   -   -   [1]
51 
 279   Urine sample   -   -   -   -   [3]
49,
51,
61 
 280   Ut-15 sr   -   -   -   -   [1]
51 
 281   Ut-15c sr   -   -   -   -   [2]
51,
86 
 282   Ut-15c-sr   -   -   -   -   [1]
51 
 283   Vib7734   -   -   -   -   [4]
49,
50,
51,
53 
 284   Vivomixx probiotics   -   -   -   -   [1]
51 
 285   Volibris   Ambrisentan   D07077   [1] EDNRA   [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [3]
51,
86,
88 
 286   Yellow fever vaccine   Yellow fever vaccine   D06347   -   -   [7]
40,
44,
46,
50,
51,
52,
53 
 287   Yellow fever vaccine (17d)   Yellow fever vaccine   D06347   -   -   [7]
40,
44,
46,
50,
51,
52,
53 

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