DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway

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11 / 275 pathways found* Show info (disease name, etc.) on mouse-over.

No.	KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related	KEGG GENES * [Number of genes]	KEGG DRUG *	DrugBank	Disease ID * [Number of diseases]
1	Adrenergic signaling in cardiomyocytes 1 gene, 1 drug (DrugBank), 13 diseases shown	[1] ADRB2	D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
2	Calcium signaling pathway 1 gene, 1 drug (DrugBank), 13 diseases shown	[1] ADRB2	D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
3	cAMP signaling pathway 1 gene, 1 drug (DrugBank), 13 diseases shown	[1] ADRB2	D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
4	cGMP-PKG signaling pathway 1 gene, 1 drug (DrugBank), 13 diseases shown	[1] ADRB2	D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
5	Cortisol synthesis and secretion 1 gene, 1 drug (DrugBank), 3 diseases shown	[1] KCNA4	D10228	Amifampridine	[3] 3, 11, 12
6	Cushing syndrome 1 gene, 1 drug (DrugBank), 3 diseases shown	[1] KCNA4	D10228	Amifampridine	[3] 3, 11, 12
7	Neuroactive ligand-receptor interaction 1 gene, 1 drug (DrugBank), 13 diseases shown	[1] ADRB2	D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
8	Regulation of lipolysis in adipocytes 1 gene, 1 drug (DrugBank), 13 diseases shown	[1] ADRB2	D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
9	Renin secretion 1 gene, 1 drug (DrugBank), 13 diseases shown	[1] ADRB2	D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
10	Salivary secretion 1 gene, 1 drug (DrugBank), 13 diseases shown	[1] ADRB2	D02147	Salbutamol	[13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299
11	Serotonergic synapse 1 gene, 1 drug (DrugBank), 3 diseases shown	[1] KCND2	D10228	Amifampridine	[3] 3, 11, 12