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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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25 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  AGE-RAGE signaling pathway in diabetic complications 
 2 genes, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D05697   Ranibizumab   [4] 34, 166, 227, 301 
 [2] VEGFA, VEGFB   D09574   Aflibercept   [2] 90, 166 
 2  Bladder cancer 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 3  Collecting duct acid secretion 
 2 genes, 1 drug (DrugBank), 6 diseases shown 		  [2] ATP4A, ATP4B   D00355   Lansoprazole   [6] 63, 71, 98, 166, 222, 299 
 4  EGFR tyrosine kinase inhibitor resistance 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 5  Fluid shear stress and atherosclerosis 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 6  Focal adhesion 
 3 genes, 2 drugs (DrugBank), 5 diseases shown 		  [3] PGF, VEGFA, VEGFB   D09574   Aflibercept   [2] 90, 166 
 [1] VEGFA   D05697   Ranibizumab   [4] 34, 166, 227, 301 
 7  Gastric acid secretion 
 2 genes, 1 drug (DrugBank), 6 diseases shown 		  [2] ATP4A, ATP4B   D00355   Lansoprazole   [6] 63, 71, 98, 166, 222, 299 
 8  HIF-1 signaling pathway 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 9  Human cytomegalovirus infection 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 10  Human papillomavirus infection 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 11  Kaposi sarcoma-associated herpesvirus infection 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 12  MAPK signaling pathway 
 3 genes, 2 drugs (DrugBank), 5 diseases shown 		  [3] PGF, VEGFA, VEGFB   D09574   Aflibercept   [2] 90, 166 
 [1] VEGFA   D05697   Ranibizumab   [4] 34, 166, 227, 301 
 13  Metabolic pathways 
 2 genes, 1 drug (DrugBank), 6 diseases shown 		  [2] ATP4A, ATP4B   D00355   Lansoprazole   [6] 63, 71, 98, 166, 222, 299 
 14  MicroRNAs in cancer 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 15  Oxidative phosphorylation 
 2 genes, 1 drug (DrugBank), 6 diseases shown 		  [2] ATP4A, ATP4B   D00355   Lansoprazole   [6] 63, 71, 98, 166, 222, 299 
 16  Pancreatic cancer 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 17  Pathways in cancer 
 3 genes, 2 drugs (DrugBank), 5 diseases shown 		  [3] PGF, VEGFA, VEGFB   D09574   Aflibercept   [2] 90, 166 
 [1] VEGFA   D05697   Ranibizumab   [4] 34, 166, 227, 301 
 18  PI3K-Akt signaling pathway 
 3 genes, 2 drugs (DrugBank), 5 diseases shown 		  [3] PGF, VEGFA, VEGFB   D09574   Aflibercept   [2] 90, 166 
 [1] VEGFA   D05697   Ranibizumab   [4] 34, 166, 227, 301 
 19  Proteoglycans in cancer 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 20  Rap1 signaling pathway 
 3 genes, 2 drugs (DrugBank), 5 diseases shown 		  [3] PGF, VEGFA, VEGFB   D09574   Aflibercept   [2] 90, 166 
 [1] VEGFA   D05697   Ranibizumab   [4] 34, 166, 227, 301 
 21  Ras signaling pathway 
 3 genes, 2 drugs (DrugBank), 5 diseases shown 		  [3] PGF, VEGFA, VEGFB   D09574   Aflibercept   [2] 90, 166 
 [1] VEGFA   D05697   Ranibizumab   [4] 34, 166, 227, 301 
 22  Relaxin signaling pathway 
 2 genes, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D05697   Ranibizumab   [4] 34, 166, 227, 301 
 [2] VEGFA, VEGFB   D09574   Aflibercept   [2] 90, 166 
 23  Renal cell carcinoma 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 24  Rheumatoid arthritis 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 
 25  VEGF signaling pathway 
 1 gene, 2 drugs (DrugBank), 5 diseases shown 		  [1] VEGFA   D09574   Aflibercept   [2] 90, 166 
 D05697   Ranibizumab   [4] 34, 166, 227, 301 

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