No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * [Number of genes] |
KEGG DRUG * |
DrugBank |
Disease ID * [Number of diseases] |
1 | Adherens junction 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
2 | Adipocytokine signaling pathway 5 genes, 4 drugs (DrugBank), 25 diseases shown |
[1] JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
[1] LEPR |
D05014 |
Metreleptin |
[1] 265 |
[1] PPARA |
D00565 |
Fenofibrate |
[5] 8, 79, 93, 94, 265 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
3 | AGE-RAGE signaling pathway in diabetic complications 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
4 | AMPK signaling pathway 6 genes, 8 drugs (DrugBank), 46 diseases shown |
[1] HMGCR |
D00887 |
Atorvastatin |
[17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00893 |
Pravastatin |
[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D00434 |
Simvastatin |
[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[1] LEPR |
D05014 |
Metreleptin |
[1] 265 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
[5] 46, 75, 97, 222, 265 |
D08491 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
5 | Apelin signaling pathway 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
6 | Autophagy - animal 3 genes, 2 drugs (DrugBank), 21 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
7 | Bile secretion 2 genes, 5 drugs (DrugBank), 35 diseases shown |
[1] HMGCR |
D00887 |
Atorvastatin |
[17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00893 |
Pravastatin |
[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D00434 |
Simvastatin |
[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
[1] NR1H4 |
D10699 |
Cholic Acid |
[4] 20, 234, 265, 310 |
D09360 |
Obeticholic acid |
[3] 93, 265, 296 |
8 | Breast cancer 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
9 | cAMP signaling pathway 1 gene, 1 drug (DrugBank), 5 diseases shown |
[1] PPARA |
D00565 |
Fenofibrate |
[5] 8, 79, 93, 94, 265 |
10 | Chemokine signaling pathway 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
11 | Cholesterol metabolism 1 gene, 1 drug (DrugBank), 1 disease shown |
[1] APOC3 |
D11648 |
Volanesorsen |
[1] 265 |
12 | Cholinergic synapse 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
13 | Circadian rhythm 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
14 | Cytokine-cytokine receptor interaction 2 genes, 3 drugs (DrugBank), 20 diseases shown |
[1] GHR |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
[1] LEPR |
D05014 |
Metreleptin |
[1] 265 |
15 | EGFR tyrosine kinase inhibitor resistance 3 genes, 2 drugs (DrugBank), 13 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
16 | Endocrine resistance 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
17 | Endocytosis 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
18 | Epstein-Barr virus infection 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK1 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
19 | Fluid shear stress and atherosclerosis 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
20 | Focal adhesion 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
21 | FoxO signaling pathway 3 genes, 2 drugs (DrugBank), 21 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
22 | Glioma 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
23 | Glucagon signaling pathway 3 genes, 2 drugs (DrugBank), 21 diseases shown |
[1] PPARA |
D00565 |
Fenofibrate |
[5] 8, 79, 93, 94, 265 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
24 | Growth hormone synthesis, secretion and action 3 genes, 4 drugs (DrugBank), 26 diseases shown |
[1] GHR |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
[1] GHRHR |
D06655 |
Tesamorelin |
[2] 78, 265 |
[1] JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
25 | Hepatitis B 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
26 | Hepatitis C 2 genes, 2 drugs (DrugBank), 11 diseases shown |
[1] JAK1 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
[1] PPARA |
D00565 |
Fenofibrate |
[5] 8, 79, 93, 94, 265 |
27 | Hepatocellular carcinoma 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
28 | Herpes simplex virus 1 infection 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
29 | HIF-1 signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
30 | Human cytomegalovirus infection 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK1 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
31 | Human papillomavirus infection 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK1 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
32 | Human T-cell leukemia virus 1 infection 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK1 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
33 | Huntington disease 1 gene, 2 drugs (DrugBank), 20 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
[5] 46, 75, 97, 222, 265 |
D08491 |
34 | Hypertrophic cardiomyopathy (HCM) 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
35 | Influenza A 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
36 | Insulin resistance 3 genes, 2 drugs (DrugBank), 21 diseases shown |
[1] PPARA |
D00565 |
Fenofibrate |
[5] 8, 79, 93, 94, 265 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
37 | Insulin signaling pathway 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
38 | JAK-STAT signaling pathway 4 genes, 4 drugs (DrugBank), 26 diseases shown |
[1] GHR |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
[1] LEPR |
D05014 |
Metreleptin |
[1] 265 |
39 | Kaposi sarcoma-associated herpesvirus infection 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
40 | Leishmaniasis 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
41 | Long-term depression 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
42 | Longevity regulating pathway 4 genes, 4 drugs (DrugBank), 28 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
[5] 46, 75, 97, 222, 265 |
D08491 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
43 | Longevity regulating pathway - multiple species 3 genes, 2 drugs (DrugBank), 21 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
44 | MAPK signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
45 | Measles 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK1 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
46 | Melanoma 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
47 | Metabolic pathways 1 gene, 3 drugs (DrugBank), 32 diseases shown |
[1] HMGCR |
D00887 |
Atorvastatin |
[17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00893 |
Pravastatin |
[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D00434 |
Simvastatin |
[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
48 | mTOR signaling pathway 3 genes, 2 drugs (DrugBank), 21 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
49 | Necroptosis 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
50 | Neuroactive ligand-receptor interaction 3 genes, 4 drugs (DrugBank), 20 diseases shown |
[1] GHR |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
[1] GHRHR |
D06655 |
Tesamorelin |
[2] 78, 265 |
[1] LEPR |
D05014 |
Metreleptin |
[1] 265 |
51 | NOD-like receptor signaling pathway 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK1 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
52 | Non-alcoholic fatty liver disease (NAFLD) 4 genes, 3 drugs (DrugBank), 21 diseases shown |
[1] LEPR |
D05014 |
Metreleptin |
[1] 265 |
[1] PPARA |
D00565 |
Fenofibrate |
[5] 8, 79, 93, 94, 265 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
53 | Oocyte meiosis 2 genes, 2 drugs (DrugBank), 11 diseases shown |
[1] AR |
D00075 |
Testosterone |
[7] 1, 2, 3, 13, 78, 113, 265 |
D00957 |
D00958 |
D00959 |
D06085 |
D06087 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
54 | Osteoclast differentiation 2 genes, 3 drugs (DrugBank), 25 diseases shown |
[1] JAK1 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
[5] 46, 75, 97, 222, 265 |
D08491 |
55 | Ovarian steroidogenesis 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
56 | Oxytocin signaling pathway 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
57 | Pancreatic cancer 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK1 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
58 | Pathways in cancer 5 genes, 5 drugs (DrugBank), 29 diseases shown |
[1] AR |
D00075 |
Testosterone |
[7] 1, 2, 3, 13, 78, 113, 265 |
D00957 |
D00958 |
D00959 |
D06085 |
D06087 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
[5] 46, 75, 97, 222, 265 |
D08491 |
59 | PD-L1 expression and PD-1 checkpoint pathway in cancer 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
60 | PI3K-Akt signaling pathway 6 genes, 4 drugs (DrugBank), 36 diseases shown |
[1] GHR |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
[2] GHR, IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
61 | PPAR signaling pathway 3 genes, 4 drugs (DrugBank), 24 diseases shown |
[1] APOC3 |
D11648 |
Volanesorsen |
[1] 265 |
[1] PPARA |
D00565 |
Fenofibrate |
[5] 8, 79, 93, 94, 265 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
[5] 46, 75, 97, 222, 265 |
D08491 |
62 | Progesterone-mediated oocyte maturation 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
63 | Prolactin signaling pathway 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
64 | Prostate cancer 2 genes, 2 drugs (DrugBank), 11 diseases shown |
[1] AR |
D00075 |
Testosterone |
[7] 1, 2, 3, 13, 78, 113, 265 |
D00957 |
D00958 |
D00959 |
D06085 |
D06087 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
65 | Proteoglycans in cancer 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
66 | Rap1 signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
67 | Ras signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
68 | Signaling pathways regulating pluripotency of stem cells 3 genes, 2 drugs (DrugBank), 13 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
69 | Terpenoid backbone biosynthesis 1 gene, 3 drugs (DrugBank), 32 diseases shown |
[1] HMGCR |
D00887 |
Atorvastatin |
[17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00893 |
Pravastatin |
[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D00434 |
Simvastatin |
[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
70 | Th1 and Th2 cell differentiation 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
71 | Th17 cell differentiation 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
72 | Thermogenesis 3 genes, 3 drugs (DrugBank), 27 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
[5] 46, 75, 97, 222, 265 |
D08491 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
73 | Thyroid cancer 1 gene, 2 drugs (DrugBank), 20 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
[5] 46, 75, 97, 222, 265 |
D08491 |
74 | Tight junction 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
75 | Toxoplasmosis 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
76 | Transcriptional misregulation in cancer 2 genes, 3 drugs (DrugBank), 21 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
[5] 46, 75, 97, 222, 265 |
D08491 |
77 | Tuberculosis 2 genes, 1 drug (DrugBank), 8 diseases shown |
[2] JAK1, JAK2 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |
78 | Viral carcinogenesis 1 gene, 1 drug (DrugBank), 8 diseases shown |
[1] JAK1 |
D10308 |
Baricitinib |
[8] 41, 46, 49, 50, 93, 107, 265, 325 |