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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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106 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Adipocytokine signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 2  African trypanosomiasis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 3  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 4  Alcoholism 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] DRD2   D00799   Trifluoperazine   [2] 283, 284 
 D01448 
 D08636 
 5  Allograft rejection 
 3 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 6  Alzheimer disease 
 6 genes, 3 drugs (DrugBank), 58 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 7  Amoebiasis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 8  Amphetamine addiction 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 9  Amyotrophic lateral sclerosis (ALS) 
 6 genes, 3 drugs (DrugBank), 58 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 10  Antifolate resistance 
 3 genes, 2 drugs (DrugBank), 37 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 11  Antigen processing and presentation 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 12  Apoptosis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 13  Asthma 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 14  Autoimmune thyroid disease 
 2 genes, 1 drug (DrugBank), 24 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 15  Axon guidance 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 16  B cell receptor signaling pathway 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 17  C-type lectin receptor signaling pathway 
 6 genes, 3 drugs (DrugBank), 58 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 18  Calcium signaling pathway 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 19  cAMP signaling pathway 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] DRD2   D00799   Trifluoperazine   [2] 283, 284 
 D01448 
 D08636 
 20  Cell adhesion molecules (CAMs) 
 3 genes, 2 drugs (DrugBank), 25 diseases shown 		  [1] CD58   D02800   Alefacept   [6] 37, 60, 65, 164, 284, 285 
 [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 21  Cellular senescence 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 22  cGMP-PKG signaling pathway 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 23  Chagas disease (American trypanosomiasis) 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 24  Cocaine addiction 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] DRD2   D00799   Trifluoperazine   [2] 283, 284 
 D01448 
 D08636 
 25  Cytokine-cytokine receptor interaction 
 4 genes, 4 drugs (DrugBank), 32 diseases shown 		  [1] ACVR2A   D09670   Sotatercept   [2] 86, 284 
 [1] CSF3R   D03235   Filgrastim   [28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 26  Dilated cardiomyopathy (DCM) 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 27  Dopaminergic synapse 
 4 genes, 3 drugs (DrugBank), 55 diseases shown 		  [1] DRD2   D00799   Trifluoperazine   [2] 283, 284 
 D01448 
 D08636 
 [3] PPP3CA, PPP3CB, PPP3CC   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 28  Drug metabolism - other enzymes 
 4 genes, 4 drugs (DrugBank), 39 diseases shown 		  [2] IMPDH1, IMPDH2   D00752   Mycophenolate mofetil   [32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   [34] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 [1] RRM1   D01907   Fludarabine   [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 29  Endocytosis 
 1 gene, 1 drug (DrugBank), 7 diseases shown 		  [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 30  Epstein-Barr virus infection 
 2 genes, 2 drugs (DrugBank), 13 diseases shown 		  [1] CD58   D02800   Alefacept   [6] 37, 60, 65, 164, 284, 285 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 31  Fc epsilon RI signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 32  Fluid shear stress and atherosclerosis 
 2 genes, 2 drugs (DrugBank), 9 diseases shown 		  [1] ACVR2A   D09670   Sotatercept   [2] 86, 284 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 33  Folate biosynthesis 
 2 genes, 1 drug (DrugBank), 33 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 34  Gap junction 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] DRD2   D00799   Trifluoperazine   [2] 283, 284 
 D01448 
 D08636 
 35  Glucagon signaling pathway 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 36  Glutamatergic synapse 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 37  Glutathione metabolism 
 2 genes, 2 drugs (DrugBank), 21 diseases shown 		  [1] RRM1   D01907   Fludarabine   [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 38  Graft-versus-host disease 
 3 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 39  Hematopoietic cell lineage 
 4 genes, 4 drugs (DrugBank), 55 diseases shown 		  [1] CSF3R   D03235   Filgrastim   [28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 [1] MS4A1   D02994   Rituximab   [42] 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 40  Hepatitis B 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 41  Hepatitis C 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 42  Herpes simplex virus 1 infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 43  Human cytomegalovirus infection 
 6 genes, 3 drugs (DrugBank), 58 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 44  Human immunodeficiency virus 1 infection 
 6 genes, 3 drugs (DrugBank), 58 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 45  Human papillomavirus infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 46  Human T-cell leukemia virus 1 infection 
 7 genes, 4 drugs (DrugBank), 58 diseases shown 		  [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 47  Hypertrophic cardiomyopathy (HCM) 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 48  IL-17 signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 49  Inflammatory bowel disease (IBD) 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 50  Influenza A 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 51  Insulin resistance 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 52  Intestinal immune network for IgA production 
 2 genes, 1 drug (DrugBank), 24 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 53  JAK-STAT signaling pathway 
 2 genes, 2 drugs (DrugBank), 30 diseases shown 		  [1] CSF3R   D03235   Filgrastim   [28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 54  Kaposi sarcoma-associated herpesvirus infection 
 6 genes, 3 drugs (DrugBank), 61 diseases shown 		  [1] CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 55  Legionellosis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 56  Leishmaniasis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 57  Long-term potentiation 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 58  Malaria 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 59  MAPK signaling pathway 
 6 genes, 3 drugs (DrugBank), 58 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 60  Measles 
 1 gene, 1 drug (DrugBank), 7 diseases shown 		  [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 61  Metabolic pathways 
 6 genes, 5 drugs (DrugBank), 51 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 [2] IMPDH1, IMPDH2   D00752   Mycophenolate mofetil   [32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   [34] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 [1] RRM1   D01907   Fludarabine   [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 62  mTOR signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 63  Natural killer cell mediated cytotoxicity 
 6 genes, 3 drugs (DrugBank), 58 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 64  Necroptosis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 65  Neuroactive ligand-receptor interaction 
 2 genes, 3 drugs (DrugBank), 52 diseases shown 		  [1] DRD2   D00799   Trifluoperazine   [2] 283, 284 
 D01448 
 D08636 
 [1] NR3C1   D00407   Methylprednisolone   [36] 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 
 D00751 
 D00979 
 D05000 
 D05001 
 D05002 
 D00473   Prednisone   [44] 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 
 66  NF-kappa B signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 67  NOD-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 68  Non-alcoholic fatty liver disease (NAFLD) 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 69  One carbon pool by folate 
 2 genes, 1 drug (DrugBank), 33 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 70  Oocyte meiosis 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 71  Osteoclast differentiation 
 6 genes, 3 drugs (DrugBank), 58 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 72  Oxytocin signaling pathway 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 73  p53 signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 74  Parkinson disease 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] DRD2   D00799   Trifluoperazine   [2] 283, 284 
 D01448 
 D08636 
 75  Pathogenic Escherichia coli infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 76  Pathways in cancer 
 2 genes, 2 drugs (DrugBank), 30 diseases shown 		  [1] CSF3R   D03235   Filgrastim   [28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 77  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 78  Pertussis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 79  PI3K-Akt signaling pathway 
 2 genes, 2 drugs (DrugBank), 30 diseases shown 		  [1] CSF3R   D03235   Filgrastim   [28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 80  Proteoglycans in cancer 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 81  Purine metabolism 
 4 genes, 4 drugs (DrugBank), 39 diseases shown 		  [2] IMPDH1, IMPDH2   D00752   Mycophenolate mofetil   [32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   [34] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 [1] RRM1   D01907   Fludarabine   [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 82  Pyrimidine metabolism 
 2 genes, 2 drugs (DrugBank), 21 diseases shown 		  [1] RRM1   D01907   Fludarabine   [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 83  Rap1 signaling pathway 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] DRD2   D00799   Trifluoperazine   [2] 283, 284 
 D01448 
 D08636 
 84  Renin secretion 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 85  Rheumatoid arthritis 
 3 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 86  RIG-I-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 87  Shigellosis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 88  Signaling pathways regulating pluripotency of stem cells 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] ACVR2A   D09670   Sotatercept   [2] 86, 284 
 89  Sphingolipid signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 90  Systemic lupus erythematosus 
 3 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 91  T cell receptor signaling pathway 
 6 genes, 3 drugs (DrugBank), 58 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 92  TGF-beta signaling pathway 
 2 genes, 2 drugs (DrugBank), 9 diseases shown 		  [1] ACVR2A   D09670   Sotatercept   [2] 86, 284 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 93  Th1 and Th2 cell differentiation 
 6 genes, 3 drugs (DrugBank), 55 diseases shown 		  [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 94  Th17 cell differentiation 
 6 genes, 3 drugs (DrugBank), 55 diseases shown 		  [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 95  TNF signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 96  Toll-like receptor signaling pathway 
 3 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 97  Toxoplasmosis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 98  Transcriptional misregulation in cancer 
 1 gene, 1 drug (DrugBank), 24 diseases shown 		  [1] CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 99  Tuberculosis 
 6 genes, 3 drugs (DrugBank), 58 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 100  Type I diabetes mellitus 
 3 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 101  Type II diabetes mellitus 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 102  VEGF signaling pathway 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 103  Viral myocarditis 
 2 genes, 1 drug (DrugBank), 24 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 104  Viral protein interaction with cytokine and cytokine receptor 
 2 genes, 2 drugs (DrugBank), 14 diseases shown 		  [1] IL2RA   D03639   Daclizumab   [7] 13, 56, 60, 65, 97, 283, 284 
 [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 
 105  Wnt signaling pathway 
 5 genes, 2 drugs (DrugBank), 55 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 D00107   Tacrolimus   [30] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 106  Yersinia infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] TNF   D04687   Lenalidomide   [8] 16, 26, 28, 34, 49, 96, 284, 300 

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