Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D01227	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
2	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D07077	Ambrisentan	7件: 51, 84, 85, 86, 88, 210, 211
3	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D07538	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
4	EDNRB	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D01227	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
5	EDNRB	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D07538	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
6	NR3C1	1件: Neuroactive ligand-receptor interaction	D00407	Methylprednisolone	9件: 211, 220, 222, 224, 271, 283, 284, 285, 296
7	NR3C1	1件: Neuroactive ligand-receptor interaction	D05000	Methylprednisolone hemisuccinate	1件: 211
8	AR	4件: Oocyte meiosis, Pathways in cancer, Chemical carcinogenesis - receptor activation, Prostate canc ...	D00462	Oxandrolone	2件: 211, 285
9	PDE5A	3件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway	D08514	Sildenafil	17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301

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