Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Calcium signaling pathway 💬	1件: EDNRA 💬	D07077 💬	Ambrisentan	7件: 51, 84, 85, 86, 88, 210, 211 💬
2	Calcium signaling pathway 💬	2件: EDNRA, EDNRB 💬	D01227 💬	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
3	Calcium signaling pathway 💬	2件: EDNRA, EDNRB 💬	D07538 💬	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
4	cAMP signaling pathway 💬	1件: EDNRA 💬	D07077 💬	Ambrisentan	7件: 51, 84, 85, 86, 88, 210, 211 💬
5	cAMP signaling pathway 💬	1件: EDNRA 💬	D01227 💬	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
6	cAMP signaling pathway 💬	1件: EDNRA 💬	D07538 💬	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
7	cGMP-PKG signaling pathway 💬	1件: EDNRA 💬	D07077 💬	Ambrisentan	7件: 51, 84, 85, 86, 88, 210, 211 💬
8	cGMP-PKG signaling pathway 💬	2件: EDNRA, EDNRB 💬	D01227 💬	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
9	cGMP-PKG signaling pathway 💬	2件: EDNRA, EDNRB 💬	D07538 💬	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
10	cGMP-PKG signaling pathway 💬	1件: PDE5A 💬	D08514 💬	Sildenafil	17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬

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