Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 F8 1件: Complement and coagulation cascades D00291 Desmopressin 1件: 288
2 F9 1件: Complement and coagulation cascades D10821 Emicizumab 1件: 288
3 F10 1件: Complement and coagulation cascades D10821 Emicizumab 1件: 288
4 NR3C1 1件: Neuroactive ligand-receptor interaction D00473 Prednisone 5件: 288, 299, 300, 307, 331
5 HMGCR 4件: Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion D00434 Simvastatin 21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
6 IL11RA 3件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage D05266 Oprelvekin 2件: 96, 288
7 PLG 4件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A D01136 Tranexamic acid 7件: 46, 70, 215, 227, 274, 288, 299
8 AVPR2 3件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vasopressin-regulated water reabsorption D00291 Desmopressin 6件: 6, 64, 72, 75, 225, 288
9 PSMB5 8件: Proteasome, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases D03150 Bortezomib 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331
10 MS4A1 1件: Hematopoietic cell lineage D02994 Rituximab 4件: 288, 296, 300, 331