Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 |
2 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
3 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 |
4 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
5 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F10 2件: F10, F9 💬 |
D10821 D10821 💬 |
Emicizumab | 288 1件: 288 💬 |
6 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F8 1件: F8 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
7 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
8 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL11RA 1件: IL11RA 💬 |
D05266 D05266 💬 |
Oprelvekin | 096 2件: 96, 288 💬 |
9 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL11RA 1件: IL11RA 💬 |
D05266 D05266 💬 |
Oprelvekin | 096 2件: 96, 288 💬 |
10 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
MS4A1 1件: MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 011 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
11 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 |
12 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
13 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IL11RA 1件: IL11RA 💬 |
D05266 D05266 💬 |
Oprelvekin | 096 2件: 96, 288 💬 |
14 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
15 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AVPR2 1件: AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
16 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 45件: 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 |
17 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
18 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 |
19 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 |
20 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AVPR2 1件: AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
21 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 |
22 | Proteasome 💬 Related to 2 target genes, 5 drugs (DrugBank) and 20 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 |
23 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 |
24 | Staphylococcus aureus infection 💬 Related to 12 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
25 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
26 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 1件: AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |