Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	NQO1	7件: Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofacto ...	D08682	Warfarin	11件: 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91
2	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D01227	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
3	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D07077	Ambrisentan	7件: 51, 84, 85, 86, 88, 210, 211
4	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D07538	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
5	EDNRA	7件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D10135	Macitentan	5件: 51, 85, 86, 88, 210
6	EDNRB	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D01227	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
7	EDNRB	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D07538	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
8	EDNRB	6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, ...	D10135	Macitentan	5件: 51, 85, 86, 88, 210
9	F10	1件: Complement and coagulation cascades	D09710	Edoxaban	1件: 88
10	ABL1	11件: ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...	D08066	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162

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