Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	1件: KIT 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2	AMPK signaling pathway 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
3	Axon guidance 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
4	Bile secretion 💬	1件: HMGCR 💬	D07474 💬	Atorvastatin	19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
5	Biosynthesis of cofactors 💬	2件: NQO1, VKORC1 💬	D08682 💬	Warfarin	11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
6	Breast cancer 💬	1件: KIT 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
7	Calcium signaling pathway 💬	1件: EDNRA 💬	D07077 💬	Ambrisentan	7件: 51, 84, 85, 86, 88, 210, 211 💬
8	Calcium signaling pathway 💬	2件: EDNRA, EDNRB 💬	D01227 💬	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
9	Calcium signaling pathway 💬	2件: EDNRA, EDNRB 💬	D07538 💬	Bosentan	10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
10	Calcium signaling pathway 💬	2件: EDNRA, EDNRB 💬	D10135 💬	Macitentan	5件: 51, 85, 86, 88, 210 💬

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