Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ERBB2 4件: Platinum drug resistance, Tight junction, Proteoglycans in cancer, Prostate cancer D08108 Lapatinib 3件: 34, 74, 75
2 ERBB2 4件: Platinum drug resistance, Tight junction, Proteoglycans in cancer, Prostate cancer D08950 Neratinib 1件: 34
3 ERBB2 4件: Platinum drug resistance, Tight junction, Proteoglycans in cancer, Prostate cancer D11772 Tesevatinib 1件: 67
4 MAP3K5 7件: Platinum drug resistance, Sphingolipid signaling pathway, Protein processing in endoplasmic reticulum, Tight junction, TNF signaling pathway, Thermogenesis, Spinocerebellar ataxia D10988 Selonsertib 1件: 86
5 PIK3CA 26件: Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11011 Alpelisib 1件: 138
6 PIK3CA 26件: Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
7 PIK3CB 26件: Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
8 PIK3CD 26件: Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
9 PIK3CD 26件: Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11437 Parsaclisib 3件: 35, 53, 61
10 BCL2 9件: Platinum drug resistance, Sphingolipid signaling pathway, Protein processing in endoplasmic reticulum, Shigellosis, Salmonella infection, Toxoplasmosis, Tuberculosis, Prostate cancer, Small cell lung cancer D10679 Venetoclax 1件: 28
11 TOP2A 1件: Platinum drug resistance D00125 Etoposide 11件: 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331
12 TOP2A 1件: Platinum drug resistance D03730 Dexrazoxane 1件: 13
13 TOP2A 1件: Platinum drug resistance D03899 Doxorubicin 5件: 26, 28, 34, 65, 331
14 TOP2A 1件: Platinum drug resistance D05522 Pixantrone 2件: 11, 13
15 TOP2A 1件: Platinum drug resistance D07776 Daunorubicin 1件: 65
16 TOP2A 1件: Platinum drug resistance D08224 Mitoxantrone 1件: 13
17 TOP2B 1件: Platinum drug resistance D00125 Etoposide 11件: 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331
18 TOP2B 1件: Platinum drug resistance D03730 Dexrazoxane 1件: 13
19 TOP2B 1件: Platinum drug resistance D03899 Doxorubicin 5件: 26, 28, 34, 65, 331
20 TOP2B 1件: Platinum drug resistance D05522 Pixantrone 2件: 11, 13
21 TOP2B 1件: Platinum drug resistance D07776 Daunorubicin 1件: 65
22 TOP2B 1件: Platinum drug resistance D08224 Mitoxantrone 1件: 13
23 CASP9 9件: Platinum drug resistance, VEGF signaling pathway, Thyroid hormone signaling pathway, Prion disease, Toxoplasmosis, Tuberculosis, Prostate cancer, Small cell lung cancer, Viral myocarditis D11195 Rimiducid 6件: 19, 60, 65, 284, 285, 326