Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 SIGMAR1 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2 SIGMAR1 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases D07945 Fenfluramine 4件: 140, 144, 145, 149
3 SIGMAR1 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases D11383 Blarcamesine 1件: 156
4 SLC22A12 - D01056 Benzbromarone 1件: 86
5 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10001 Fingolimod 3件: 13, 14, 156
6 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10905 Amiselimod 1件: 97
7 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10930 Etrasimod 3件: 96, 97, 98
8 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10968 Ozanimod 3件: 13, 96, 97
9 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D11215 Ponesimod 1件: 13
10 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D11283 Cenerimod 1件: 49
11 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D11460 Siponimod 2件: 13, 50
12 S1PR3 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10905 Amiselimod 1件: 97
13 S1PR3 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10930 Etrasimod 3件: 96, 97, 98
14 S1PR3 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10968 Ozanimod 3件: 13, 96, 97
15 SV2C 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149
16 SIGLEC8 - D11906 Lirentelimab 1件: 98
17 SERPIND1 1件: Complement and coagulation cascades D08547 Sulodexide 2件: 51, 271
18 SMAD7 2件: TGF-beta signaling pathway, Hippo signaling pathway D10956 Mongersen 2件: 96, 97
19 SERPINC1 1件: Complement and coagulation cascades D07510 Heparin 11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317
20 SERPINC1 1件: Complement and coagulation cascades D07510 Enoxaparin 1件: 46
21 SERPINC1 1件: Complement and coagulation cascades D07510 Parnaparin 1件: 97
22 SERPINC1 1件: Complement and coagulation cascades D08547 Sulodexide 2件: 51, 271
23 SOST 2件: Wnt signaling pathway, Parathyroid hormone synthesis, secretion and action D10156 Romosozumab 1件: 274
24 S1PR5 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10905 Amiselimod 1件: 97
25 S1PR5 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10930 Etrasimod 3件: 96, 97, 98
26 S1PR5 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10968 Ozanimod 3件: 13, 96, 97
27 S1PR5 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D11460 Siponimod 2件: 13, 50
28 SLAMF7 - D09337 Elotuzumab 1件: 28
29 SORT1 3件: Lysosome, Neurotrophin signaling pathway, Cholesterol metabolism D12427 Latozinemab 2件: 2, 127
30 SCN1A 1件: Dopaminergic synapse D00252 Carbamazepine 3件: 6, 13, 231
31 SCN1A 1件: Dopaminergic synapse D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
32 SCN1A 1件: Dopaminergic synapse D00358 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
33 SCN1A 1件: Dopaminergic synapse D00512 Phenytoin 1件: 13
34 SCN1A 1件: Dopaminergic synapse D00533 Oxcarbazepine 1件: 13
35 SCN1A 1件: Dopaminergic synapse D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
36 SCN1A 1件: Dopaminergic synapse D00538 Zonisamide 1件: 6
37 SCN1A 1件: Dopaminergic synapse D02910 Amiodarone 2件: 28, 127
38 SCN1A 1件: Dopaminergic synapse D03492 Cibenzoline 1件: 58
39 SCN1A 1件: Dopaminergic synapse D05775 Rufinamide 1件: 144
40 SCN1A 1件: Dopaminergic synapse D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
41 SCN1A 1件: Dopaminergic synapse D07962 Flecainide 1件: 6
42 SCN1A 1件: Dopaminergic synapse D08116 Levobupivacaine 1件: 46
43 SCN1A 1件: Dopaminergic synapse D08127 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
44 SCN1A 1件: Dopaminergic synapse D08215 Mexiletine 5件: 1, 2, 10, 113, 114
45 SCN1A 1件: Dopaminergic synapse D08319 Oxybuprocaine 1件: 6
46 SCN1A 1件: Dopaminergic synapse D08458 Quinidine 3件: 2, 8, 13
47 SCN1A 1件: Dopaminergic synapse D08490 Ropivacaine 4件: 22, 36, 46, 70
48 SCN1A 1件: Dopaminergic synapse D11155 Eleclazine 1件: 58
49 SCN2A 1件: Taste transduction D00252 Carbamazepine 3件: 6, 13, 231
50 SCN2A 1件: Taste transduction D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
51 SCN2A 1件: Taste transduction D00358 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
52 SCN2A 1件: Taste transduction D00512 Phenytoin 1件: 13
53 SCN2A 1件: Taste transduction D00533 Oxcarbazepine 1件: 13
54 SCN2A 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
55 SCN2A 1件: Taste transduction D00538 Zonisamide 1件: 6
56 SCN2A 1件: Taste transduction D02910 Amiodarone 2件: 28, 127
57 SCN2A 1件: Taste transduction D03492 Cibenzoline 1件: 58
58 SCN2A 1件: Taste transduction D05775 Rufinamide 1件: 144
59 SCN2A 1件: Taste transduction D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
60 SCN2A 1件: Taste transduction D07962 Flecainide 1件: 6
61 SCN2A 1件: Taste transduction D08116 Levobupivacaine 1件: 46
62 SCN2A 1件: Taste transduction D08127 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
63 SCN2A 1件: Taste transduction D08215 Mexiletine 5件: 1, 2, 10, 113, 114
64 SCN2A 1件: Taste transduction D08319 Oxybuprocaine 1件: 6
65 SCN2A 1件: Taste transduction D08458 Quinidine 3件: 2, 8, 13
66 SCN2A 1件: Taste transduction D08490 Ropivacaine 4件: 22, 36, 46, 70
67 SCN2A 1件: Taste transduction D11155 Eleclazine 1件: 58
68 SCN3A 1件: Taste transduction D00252 Carbamazepine 3件: 6, 13, 231
69 SCN3A 1件: Taste transduction D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
70 SCN3A 1件: Taste transduction D00358 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
71 SCN3A 1件: Taste transduction D00512 Phenytoin 1件: 13
72 SCN3A 1件: Taste transduction D00533 Oxcarbazepine 1件: 13
73 SCN3A 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
74 SCN3A 1件: Taste transduction D00538 Zonisamide 1件: 6
75 SCN3A 1件: Taste transduction D02910 Amiodarone 2件: 28, 127
76 SCN3A 1件: Taste transduction D03492 Cibenzoline 1件: 58
77 SCN3A 1件: Taste transduction D05775 Rufinamide 1件: 144
78 SCN3A 1件: Taste transduction D07299 Lacosamide 4件: 2, 46, 149, 298
79 SCN3A 1件: Taste transduction D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
80 SCN3A 1件: Taste transduction D07962 Flecainide 1件: 6
81 SCN3A 1件: Taste transduction D08116 Levobupivacaine 1件: 46
82 SCN3A 1件: Taste transduction D08127 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
83 SCN3A 1件: Taste transduction D08215 Mexiletine 5件: 1, 2, 10, 113, 114
84 SCN3A 1件: Taste transduction D08319 Oxybuprocaine 1件: 6
85 SCN3A 1件: Taste transduction D08458 Quinidine 3件: 2, 8, 13
86 SCN3A 1件: Taste transduction D08490 Ropivacaine 4件: 22, 36, 46, 70
87 SCN3A 1件: Taste transduction D11155 Eleclazine 1件: 58
88 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00252 Carbamazepine 3件: 6, 13, 231
89 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
90 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00358 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
91 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00512 Phenytoin 1件: 13
92 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00533 Oxcarbazepine 1件: 13
93 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
94 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00538 Zonisamide 1件: 6
95 SCN5A 1件: Adrenergic signaling in cardiomyocytes D02910 Amiodarone 2件: 28, 127
96 SCN5A 1件: Adrenergic signaling in cardiomyocytes D03492 Cibenzoline 1件: 58
97 SCN5A 1件: Adrenergic signaling in cardiomyocytes D05775 Rufinamide 1件: 144
98 SCN5A 1件: Adrenergic signaling in cardiomyocytes D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
99 SCN5A 1件: Adrenergic signaling in cardiomyocytes D07962 Flecainide 1件: 6
100 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08116 Levobupivacaine 1件: 46
101 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08127 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
102 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08215 Mexiletine 5件: 1, 2, 10, 113, 114
103 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08319 Oxybuprocaine 1件: 6
104 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08458 Quinidine 3件: 2, 8, 13
105 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08490 Ropivacaine 4件: 22, 36, 46, 70
106 SCN5A 1件: Adrenergic signaling in cardiomyocytes D11155 Eleclazine 1件: 58
107 SCN9A 1件: Taste transduction D00252 Carbamazepine 3件: 6, 13, 231
108 SCN9A 1件: Taste transduction D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
109 SCN9A 1件: Taste transduction D00358 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
110 SCN9A 1件: Taste transduction D00512 Phenytoin 1件: 13
111 SCN9A 1件: Taste transduction D00533 Oxcarbazepine 1件: 13
112 SCN9A 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
113 SCN9A 1件: Taste transduction D00538 Zonisamide 1件: 6
114 SCN9A 1件: Taste transduction D02910 Amiodarone 2件: 28, 127
115 SCN9A 1件: Taste transduction D03492 Cibenzoline 1件: 58
116 SCN9A 1件: Taste transduction D05775 Rufinamide 1件: 144
117 SCN9A 1件: Taste transduction D07299 Lacosamide 4件: 2, 46, 149, 298
118 SCN9A 1件: Taste transduction D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
119 SCN9A 1件: Taste transduction D07962 Flecainide 1件: 6
120 SCN9A 1件: Taste transduction D08116 Levobupivacaine 1件: 46
121 SCN9A 1件: Taste transduction D08127 Lidocaine 13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
122 SCN9A 1件: Taste transduction D08215 Mexiletine 5件: 1, 2, 10, 113, 114
123 SCN9A 1件: Taste transduction D08319 Oxybuprocaine 1件: 6
124 SCN9A 1件: Taste transduction D08458 Quinidine 3件: 2, 8, 13
125 SCN9A 1件: Taste transduction D08490 Ropivacaine 4件: 22, 36, 46, 70
126 SCN9A 1件: Taste transduction D11155 Eleclazine 1件: 58
127 SCNN1A 2件: Taste transduction, Aldosterone-regulated sodium reabsorption D07447 Amiloride 4件: 13, 67, 225, 299
128 SCNN1B 2件: Taste transduction, Aldosterone-regulated sodium reabsorption D07447 Amiloride 4件: 13, 67, 225, 299
129 SCNN1G 2件: Taste transduction, Aldosterone-regulated sodium reabsorption D07447 Amiloride 4件: 13, 67, 225, 299
130 SLC5A2 - D08897 Dapagliflozin 7件: 19, 49, 66, 67, 86, 88, 222
131 SLC5A2 - D10459 Empagliflozin 6件: 58, 65, 67, 72, 97, 257
132 SLC6A1 2件: Synaptic vesicle cycle, GABAergic synapse D00332 Gabapentin 5件: 6, 13, 19, 70, 298
133 SLC6A2 1件: Synaptic vesicle cycle D00228 Amoxapine 1件: 46
134 SLC6A2 1件: Synaptic vesicle cycle D04999 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206
135 SLC6A2 1件: Synaptic vesicle cycle D05458 Phentermine 1件: 97
136 SLC6A2 1件: Synaptic vesicle cycle D07448 Amitriptyline 4件: 78, 97, 226, 299
137 SLC6A2 1件: Synaptic vesicle cycle D07473 Atomoxetine 4件: 6, 8, 13, 17
138 SLC6A2 1件: Synaptic vesicle cycle D07591 Bupropion 5件: 8, 18, 21, 96, 171
139 SLC6A2 1件: Synaptic vesicle cycle D07791 Desipramine 2件: 120, 156
140 SLC6A2 1件: Synaptic vesicle cycle D07875 Doxepin 1件: 6
141 SLC6A2 1件: Synaptic vesicle cycle D07880 Duloxetine 2件: 6, 13
142 SLC6A2 1件: Synaptic vesicle cycle D08130 Lisdexamfetamine 1件: 13
143 SLC6A2 1件: Synaptic vesicle cycle D08222 Milnacipran 2件: 46, 49
144 SLC6A2 1件: Synaptic vesicle cycle D08288 Nortriptyline 2件: 6, 226
145 SLC6A2 1件: Synaptic vesicle cycle D08670 Venlafaxine 3件: 6, 13, 46
146 SLC6A2 1件: Synaptic vesicle cycle D11688 Ampreloxetine 2件: 6, 17
147 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D03215 Armodafinil 3件: 6, 13, 84
148 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D04999 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206
149 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D05458 Phentermine 1件: 97
150 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D07591 Bupropion 5件: 8, 18, 21, 96, 171
151 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D08130 Lisdexamfetamine 1件: 13
152 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00228 Amoxapine 1件: 46
153 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00326 Fluoxetine 6件: 13, 17, 78, 86, 179, 206
154 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D02360 Sertraline 2件: 6, 206
155 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D02362 Paroxetine 4件: 6, 13, 46, 85
156 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D05458 Phentermine 1件: 97
157 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07448 Amitriptyline 4件: 78, 97, 226, 299
158 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07704 Citalopram 7件: 6, 8, 13, 18, 46, 98, 127
159 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07791 Desipramine 2件: 120, 156
160 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07875 Doxepin 1件: 6
161 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07880 Duloxetine 2件: 6, 13
162 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07913 Escitalopram 4件: 2, 6, 13, 46
163 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07945 Fenfluramine 4件: 140, 144, 145, 149
164 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D08222 Milnacipran 2件: 46, 49
165 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D08288 Nortriptyline 2件: 6, 226
166 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D08626 Trazodone 1件: 2
167 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D08670 Venlafaxine 3件: 6, 13, 46
168 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D10184 Vortioxetine 1件: 6
169 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D11688 Ampreloxetine 2件: 6, 17
170 SLC10A1 2件: Bile secretion, Hepatitis B D10951 Maralixibat 3件: 296, 297, 338
171 SLC10A2 1件: Bile secretion D10796 Elobixibat 1件: 6
172 SLC10A2 1件: Bile secretion D10951 Maralixibat 3件: 296, 297, 338
173 SLC10A2 1件: Bile secretion D11716 Odevixibat 3件: 296, 297, 338
174 SLC12A2 3件: Salivary secretion, Pancreatic secretion, Vibrio cholerae infection D00247 Bumetanide 2件: 6, 158
175 SLC12A2 3件: Salivary secretion, Pancreatic secretion, Vibrio cholerae infection D00331 Furosemide 2件: 6, 86
176 SLC12A3 - D00340 Hydrochlorothiazide 4件: 13, 67, 225, 235
177 SLC12A3 - D00345 Indapamide 1件: 13
178 SLC12A3 - D00519 Chlorothiazide 1件: 225
179 SLC12A3 - D00650 Bendroflumethiazide 1件: 67
180 SLC18A2 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism D08575 Tetrabenazine 1件: 8
181 SLC18A2 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism D10675 Valbenazine 1件: 8
182 SLC18A2 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism D10701 Deutetrabenazine 1件: 8
183 SMN1 - D11559 Onasemnogene abeparvovec 1件: 3
184 SMN2 - D10881 Nusinersen 1件: 3
185 SMN2 1件: Nucleocytoplasmic transport D11406 Risdiplam 1件: 3
186 SMN2 - D12272 Branaplam 2件: 3, 8
187 SMO 5件: Hedgehog signaling pathway, Axon guidance, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma D09992 Vismodegib 1件: 85
188 SMO 5件: Hedgehog signaling pathway, Axon guidance, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma D10671 Taladegib 1件: 85
189 SMPD1 5件: Sphingolipid metabolism, Metabolic pathways, Sphingolipid signaling pathway, Lysosome, Necroptosis D10820 Olipudase alfa 1件: 19
190 SNAP25 2件: Synaptic vesicle cycle, Insulin secretion D00783 Botulinum toxin type A 14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226
191 SNAP25 2件: Synaptic vesicle cycle, Insulin secretion D02735 Botulinum toxin type B 4件: 2, 6, 13, 51
192 SNCA 3件: Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases D11420 Prasinezumab 1件: 6
193 SOD1 8件: Peroxisome, Longevity regulating pathway - multiple species, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species D11811 Tofersen 1件: 2
194 SRC 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D03252 Bosutinib 2件: 2, 67
195 SRC 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D03658 Dasatinib 2件: 51, 85
196 SRC 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D06414 Dasatinib 2件: 51, 85
197 SRC 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D09664 Saracatinib 3件: 6, 89, 272
198 SRD5A1 2件: Steroid hormone biosynthesis, Metabolic pathways D03820 Dutasteride 2件: 1, 2
199 SRD5A2 3件: Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer D00321 Finasteride 1件: 6
200 SRD5A2 3件: Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer D03820 Dutasteride 2件: 1, 2
201 SSTR1 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D07431 Somatostatin 2件: 67, 78
202 SSTR1 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D10147 Pasireotide 3件: 67, 74, 75
203 SSTR2 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D00442 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227
204 SSTR2 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D07431 Somatostatin 2件: 67, 78
205 SSTR2 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D10147 Pasireotide 3件: 67, 74, 75
206 SSTR3 2件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D07431 Somatostatin 2件: 67, 78
207 SSTR3 2件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D10147 Pasireotide 3件: 67, 74, 75
208 SSTR4 1件: Neuroactive ligand-receptor interaction D07431 Somatostatin 2件: 67, 78
209 SSTR5 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D07431 Somatostatin 2件: 67, 78
210 SSTR5 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D10147 Pasireotide 3件: 67, 74, 75
211 SYK 17件: NF-kappa B signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Osteoclast differentiation, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease - COVID-19, Viral carcinogenesis D09347 Fostamatinib 4件: 46, 49, 61, 66
212 S1PR4 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10905 Amiselimod 1件: 97
213 S1PR4 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10930 Etrasimod 3件: 96, 97, 98
214 S1PR4 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10968 Ozanimod 3件: 13, 96, 97
215 S1PR2 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10905 Amiselimod 1件: 97
216 S1PR2 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10930 Etrasimod 3件: 96, 97, 98
217 S1PR2 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10968 Ozanimod 3件: 13, 96, 97
218 SV2B 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149
219 SV2A 1件: ECM-receptor interaction D00709 Levetiracetam 5件: 2, 4, 6, 13, 307
220 SV2A 1件: ECM-receptor interaction D08879 Brivaracetam 2件: 149, 309
221 SV2A 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149