Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CETP 1件: Cholesterol metabolism D08855 Anacetrapib 1件: 79
2 PCSK9 1件: Cholesterol metabolism D10335 Alirocumab 1件: 79
3 PCSK9 1件: Cholesterol metabolism D10557 Evolocumab 2件: 79, 222
4 PCSK9 1件: Cholesterol metabolism D11931 Inclisiran 1件: 79
5 ANGPTL3 1件: Cholesterol metabolism D11753 Evinacumab 1件: 79
6 APOC3 2件: PPAR signaling pathway, Cholesterol metabolism D11648 Volanesorsen 1件: 265
7 LIPA 3件: Steroid biosynthesis, Lysosome, Cholesterol metabolism D10377 Sebelipase alfa 1件: 19
8 SORT1 3件: Lysosome, Neurotrophin signaling pathway, Cholesterol metabolism D12427 Latozinemab 2件: 2, 127