Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
2 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
3 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
4 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
5 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
6 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
7 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
8 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
SCN5A 1件: SCN5A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 |
9 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
SCN5A 1件: SCN5A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 |
10 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
11 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
12 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
13 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
14 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
15 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
16 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
17 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
18 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
19 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
20 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
21 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
22 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
23 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
24 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
25 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
26 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
27 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 8件: 36, 37, 46, 107, 160, 162, 269, 271 💬 |
28 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
29 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
30 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
31 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
32 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
33 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
34 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
35 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
36 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
37 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
38 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
39 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
40 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
41 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
42 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
43 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
44 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
45 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
46 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 10件: 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
47 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
48 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 4件: 13, 46, 107, 271 💬 |
49 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
50 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
51 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
52 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
53 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
54 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
55 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
56 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
57 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
58 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
59 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
60 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
61 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
62 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
63 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
64 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
65 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
66 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
67 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
68 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
69 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
70 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
71 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
72 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
73 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
74 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
75 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
76 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
77 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
78 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
79 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
80 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
81 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
82 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
83 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
84 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
85 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
86 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
87 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
88 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
89 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 43 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
90 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 43 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 4件: 13, 46, 107, 271 💬 |
91 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 43 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 10件: 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
92 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
93 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
94 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
95 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
96 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
97 | Autoimmune thyroid disease 💬 Related to 22 target genes, 15 drugs (DrugBank) and 35 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
98 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
99 | B cell receptor signaling pathway 💬 Related to 19 target genes, 29 drugs (DrugBank) and 68 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
100 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
101 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
DHODH 1件: DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 |
102 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00951 D00951 💬 |
Medroxyprogesterone acetate | 013 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬 |
103 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
104 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
105 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
106 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 10件: 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
107 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
108 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 4件: 13, 46, 107, 271 💬 |
109 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
110 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
111 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
112 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
113 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
114 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
HRH2 1件: HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 6件: 6 , 46, 61, 86, 98, 107 💬 |
115 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
116 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D08860 D08860 💬 |
Apremilast | 046 7件: 46, 50, 56, 97, 107, 162, 271 💬 |
117 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
118 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
IL1A 1件: IL1A 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
119 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
120 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 |
121 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
122 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
123 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
124 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
125 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
126 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
127 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
128 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
129 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
130 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
131 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 40 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 10件: 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
132 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 40 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
133 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 40 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 4件: 13, 46, 107, 271 💬 |
134 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
135 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
136 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
PGR 1件: PGR 💬 |
D00951 D00951 💬 |
Medroxyprogesterone acetate | 013 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬 |
137 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
VDR 1件: VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬 |
138 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
139 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
JAK2 2件: JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
140 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
141 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
142 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 |
143 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
SERPINC1 1件: SERPINC1 💬 |
D07510 D07510 💬 |
Heparin | 047 11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬 |
144 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
145 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
146 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
147 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
148 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
149 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
150 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
151 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
152 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
153 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
154 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
155 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
156 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
157 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
158 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 8件: 36, 37, 46, 107, 160, 162, 269, 271 💬 |
159 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
160 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
161 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
162 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
163 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
164 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
165 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
166 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
LTA 2件: LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
167 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
168 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
169 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
170 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
171 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 12 drugs (DrugBank) and 28 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
172 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 12 drugs (DrugBank) and 28 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
173 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
174 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
175 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
176 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
177 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
178 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
179 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
180 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
SCN1A 1件: SCN1A 💬 |
D00358 D00358 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 |
181 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
SCN1A 1件: SCN1A 💬 |
D08127 D08127 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 |
182 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
183 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
184 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
185 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
186 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
187 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR 1件: VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬 |
188 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
189 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
190 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
191 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
192 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
193 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
194 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
195 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
196 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
197 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR 1件: PGR 💬 |
D00951 D00951 💬 |
Medroxyprogesterone acetate | 013 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬 |
198 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
199 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
200 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
201 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
202 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
203 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
204 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
205 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
206 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
207 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
208 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
209 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
210 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
211 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
212 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
213 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 |
214 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
HRH2 1件: HRH2 💬 |
D00318 D00318 💬 |
Famotidine | 006 6件: 6 , 46, 61, 86, 98, 107 💬 |
215 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
216 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
217 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
218 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
219 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
220 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
221 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
222 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
223 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
224 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
225 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, |