Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Aldosterone synthesis and secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 1件: 149 💬
2 Amyotrophic lateral sclerosis 💬
1件: SIGMAR1 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
3 Calcium signaling pathway 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 1件: 149 💬
4 Calcium signaling pathway 💬
2件: HTR2A, HTR2C 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
5 cAMP signaling pathway 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
6 cAMP signaling pathway 💬
1件: HTR1D 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
7 Circadian entrainment 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 1件: 149 💬
8 Cortisol synthesis and secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 1件: 149 💬
9 Cushing syndrome 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 1件: 149 💬
10 ECM-receptor interaction 💬
1件: SV2A 💬 D08879 💬 Brivaracetam 2件: 149, 309 💬
11 ECM-receptor interaction 💬
3件: SV2A, SV2B, SV2C 💬 D11842 💬 Padsevonil 1件: 149 💬
12 Estrogen signaling pathway 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
13 GABAergic synapse 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
14 Gap junction 💬
2件: HTR2A, HTR2C 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
15 GnRH secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 1件: 149 💬
16 GnRH secretion 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
17 Inflammatory mediator regulation of TRP channels 💬
2件: HTR2A, HTR2C 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
18 Insulin secretion 💬
1件: SNAP25 💬 D00783 💬 Botulinum toxin type A 14件:  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
19 MAPK signaling pathway 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 1件: 149 💬
20 Morphine addiction 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
21 Neuroactive ligand-receptor interaction 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
22 Neuroactive ligand-receptor interaction 💬
3件: HTR1D, HTR2A, HTR2C 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
23 Pathways of neurodegeneration - multiple diseases 💬
1件: SIGMAR1 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
24 Serotonergic synapse 💬
4件: HTR1D, HTR2A, HTR2C, SLC6A4 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
25 Synaptic vesicle cycle 💬
1件: SLC6A4 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
26 Synaptic vesicle cycle 💬
1件: SNAP25 💬 D00783 💬 Botulinum toxin type A 14件:  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
27 Taste transduction 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
28 Taste transduction 💬
1件: HTR1D 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
29 Taste transduction 💬
2件: SCN3A, SCN9A 💬 D07299 💬 Lacosamide 4件:  2 , 46, 149, 298 💬
30 Type II diabetes mellitus 💬
1件: CACNA1G 💬 D07971 💬 Flunarizine 1件: 149 💬