Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 SIGMAR1 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases D07945 Fenfluramine 4件: 140, 144, 145, 149
2 SV2C 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149
3 GABBR1 7件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction D00241 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206
4 HTR1D 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction D07945 Fenfluramine 4件: 140, 144, 145, 149
5 HTR2A 5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels D07945 Fenfluramine 4件: 140, 144, 145, 149
6 HTR2C 5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels D07945 Fenfluramine 4件: 140, 144, 145, 149
7 SCN3A 1件: Taste transduction D07299 Lacosamide 2件: 149, 298
8 SCN9A 1件: Taste transduction D07299 Lacosamide 2件: 149, 298
9 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07945 Fenfluramine 4件: 140, 144, 145, 149
10 SNAP25 2件: Synaptic vesicle cycle, Insulin secretion D00783 Botulinum toxin type A 14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226
11 CACNA1I 7件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome D07971 Flunarizine 1件: 149
12 CACNA1H 7件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome D07971 Flunarizine 1件: 149
13 CACNA1G 8件: MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome D07971 Flunarizine 1件: 149
14 GABBR2 7件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction D00241 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206
15 SV2B 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149
16 SV2A 1件: ECM-receptor interaction D08879 Brivaracetam 2件: 149, 309
17 SV2A 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149