Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
120 mg sildenafil citrate by mouth
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
25% sildenafil cream
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 50
3Access program - sildenafil citrate, Viagra, Revatio
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
4Bosentan and Sildenafil
(Synonym: D08514)		[2] Bosentan,
Sildenafil		[3] D01227 ,
D07538 ,
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
5Duo-Therapy with Sildenafil + Bosentan
(Synonym: D08514)		[2] Bosentan,
Sildenafil		[3] D01227 ,
D07538 ,
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
6ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(Synonym: D08514)		[4] Bosentan,
Macitentan,
Sildenafil,
Tadalafil		[5] D01227 ,
D02008 ,
D07538 ,
D08514 ,
D10135 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
7G04BE03- Sildenafil - sildenafil (citrato)
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
8Mono-Therapy with Sildenafil
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
9Oral sildenafil
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
10Sildenafil
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
11Sildenafil (50 mg)
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 85
12Sildenafil (Acute-1 hour)
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299
13Sildenafil (as citrate)
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
14Sildenafil (REVATIO)
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
15Sildenafil (Revatio) 20 mg TID
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
16Sildenafil (Subchronic-4 weeks)
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299
17Sildenafil 20 mg tablets
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 278
18Sildenafil 20mg
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 51, 86
19Sildenafil 20mg and Bosentan 62.5mg
(Synonym: D08514)		[2] Bosentan,
Sildenafil		[3] D01227 ,
D07538 ,
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86
20Sildenafil 40mg oral capsule
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299
21Sildenafil and Losartan
(Synonym: D08514)		[2] Losartan,
Sildenafil		[2] D08146 ,
D08514 		[2] AGTR1,
PDE5A 💬		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 85
22Sildenafil by injection
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 210
23Sildenafil citrate
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[4] 51, 85, 86, 225
24Sildenafil citrate (UK-92,480)
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
25Sildenafil Filmtabletten
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
26Sildenafil Oral Suspension
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 294
27Sildenafil singly or in association with Bosentan
(Synonym: D08514)		[2] Bosentan,
Sildenafil		[3] D01227 ,
D07538 ,
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
28Sildenafil therapy
(Synonym: D08514)		[1] Sildenafil[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 51
29Sitaxsentan and Sildenafil
(Synonym: D08514)		[2] Sildenafil,
Sitaxentan		[2] D07171 ,
D08514 		[2] EDNRA,
PDE5A 💬		[9] Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
30Sodium tanshinone IIA sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth
(Synonym: D08514)		[2] Dextrose, unspecified form,
Sildenafil		[1] D08514 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
31Tadalafil and Sildenafil
(Synonym: D08514)		[2] Sildenafil,
Tadalafil		[2] D02008 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 113