Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Chlorpromazine [1] Chlorpromazine[2] Chlorpromazine; Chlorpromazine Hydrochloride; [13] ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬		[22] Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 254
2 Cimetidine [1] Cimetidine[1] Cimetidine; [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 2, 254
3 Isoniazid [1] Isoniazid[1] Isoniazid; --[2] 65, 254
4 Deferasirox [1] Deferasirox[2] Deferasirox; Exjade; --[3] 254, 284, 286
5 Stannsoporfin [1] Stannsoporfin[1] Tin mesoporphyrin; [2] HMOX1,
HMOX2 💬		[10] Chemical carcinogenesis - reactive oxygen species, Ferroptosis, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatocellular carcinoma, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Pathways in cancer, Porphyrin metabolism 💬[1] 254
6 Colestipol [1] Colestipol[1] Colestipol; --[1] 254
7 Hydroxychloroquine [1] Hydroxychloroquine[3] Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; Plaquenil; --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
8 Hemin [1] Hemin[2] Hemin; Panhematin; [2] ALAS1,
ALAS2 💬		[4] Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬[1] 254
9 Afamelanotide [1] Afamelanotide[2] Afamelanotide; SCENESSE; [1] MC1R 💬[2] Melanogenesis, Neuroactive ligand-receptor interaction 💬[3] 159, 161, 254
10 Givosiran [1] Givosiran[1] Givosiran; [1] ALAS1 💬[4] Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬[1] 254