Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Folic acid [1] Folic acid[5] Acide folique; Folate; Folic acid; Multivitamin; NICOTINAMIDE; --[6] 6, 41, 46, 49, 84, 296
2 Famciclovir [1] Famciclovir[1] Famciclovir; --[2] 11, 13
3 Famotidine [1] Famotidine[2] FAMOTIDINA; Famotidine; [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[6] 6, 46, 61, 86, 98, 107
4 Fentanyl [1] Fentanyl[1] Fentanyl; [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[3] 46, 70, 215
5 Finasteride [1] Finasteride[1] Finasteride; [1] SRD5A2 💬[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[1] 6
6 Fluconazole [1] Fluconazole[2] Diflucan; FLUCONAZOLE; --[2] 96, 225
7 Fluoxetine [1] Fluoxetine[5] Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206
8 Flurbiprofen [1] Flurbiprofen[1] Flurbiprofen; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46
9 Furosemide [1] Furosemide[2] Furosemide; Furosemide Injection; [1] SLC12A2 💬[3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[2] 6, 86
10 Fenofibrate [1] Fenofibrate[1] Fenofibrate; [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265
11 Flutamide [1] Flutamide[1] Flutamide; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 81
12 Flumazenil [1] Flumazenil[1] Flumazenil; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206
13 Fomepizole [1] Fomepizole[1] 4-Methylpyrazole; [3] ADH1A,
ADH1B,
ADH1C 💬		[9] Alcoholic liver disease, Drug metabolism - cytochrome P450, Fatty acid degradation, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pyruvate metabolism, Retinol metabolism, Tyrosine metabolism 💬[1] 301
14 Flupentixol [1] Flupentixol[1] Flupentixol; [2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 97
15 Fulvestrant [1] Fulvestrant[2] Faslodex; Fulvestrant; [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 49, 86
16 Febuxostat [1] Febuxostat[1] Febuxostat; [1] XDH 💬[6] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬[3] 2, 6, 13
17 Fluorescein [1] Fluorescein[1] Fluorescein; --[2] 22, 97
18 Fluticasone propionate [1] Fluticasone propionate[3] Flovent; Fluticasone; FLUTICASONE PROPIONATE; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 98, 228
19 Fluocinolone acetonide [1] Fluocinolone acetonide[2] Fluocinolone Acetonide; Iluvien; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 90
20 Fludeoxyglucose F 18 [1] Fludeoxyglucose[1] Fludeoxyglucose; --[3] 84, 85, 88
21 Fumaric acid [1] Fumaric acid[1] Fumaric acid; --[2] 13, 49
22 Filgrastim [1] Filgrastim[7] FILGRASTIM; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio; [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
23 Fenamole [1] Fenamole[0] --[1] 160
24 Fenretinide [1] Fenretinide[1] Fenretinide; [2] RARA,
RARB 💬		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[1] 299
25 Ferric oxide [1] Ferric oxide[1] Iron oxide; --[1] 13
26 Ferumoxytol [1] Ferumoxytol[2] Feraheme; Ferumoxytol; --[1] 13
27 Floxacillin [1] Flucloxacillin[1] FLUCLOXACILLIN; --[1] 299
28 Fontolizumab [1] Fontolizumab[1] Fontolizumab; [1] IFNG 💬[32] African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 46
29 Fosfomycin [1] Fosfomycin[1] Fosfomycin; --[3] 96, 97, 222
30 Fusidic acid [1] Fusidic acid[4] Acido fusidico; Fucidin; Fusidate; FUSIDIC ACID; --[2] 272, 299
31 Firategrast [1] Firategrast[1] Firategrast; [1] ITGA4 💬[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[1] 13
32 Fesoterodine [1] Fesoterodine[1] Fesoterodine; [2] CHRM2,
CHRM3 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6
33 Fasudil [1] Fasudil[1] Fasudil; [2] ROCK1,
ROCK2 💬		[23] Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 2, 5, 7, 51
34 Fenfluramine [1] Fenfluramine[2] Fenfluramina; FENFLURAMINE; [5] HTR1D,
HTR2A,
HTR2C,
SIGMAR1,
SLC6A4 💬		[10] Amyotrophic lateral sclerosis, Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[4] 140, 144, 145, 149
35 Fexofenadine [1] Fexofenadine[1] Fexofenadine; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[2] 13, 46
36 Flavoxate [1] Flavoxate[1] Flavoxate; [16] PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		[18] Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226
37 Flecainide [1] Flecainide[3] Flecainide; FLECAINIDE ACETATE; Flecainidum; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6
38 Fludarabine [1] Fludarabine[4] FLUDARA; FLUDARABINA; Fludarabine; Fludarabine Phosphate; [1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
39 Fludrocortisone [1] Fludrocortisone[1] Fludrocortisone; [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[3] 6, 17, 81
40 Flunarizine [1] Flunarizine[0] [3] CACNA1G,
CACNA1H,
CACNA1I 💬		[8] Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GnRH secretion, MAPK signaling pathway, Type II diabetes mellitus 💬[1] 149
41 Flupirtine [1] Flupirtine[1] Flupirtine; --[1] 13
42 Fluticasone [1] Fluticasone[1] Fluticasone; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 98, 228, 299
43 Fluvastatin [1] Fluvastatin[1] Fluvastatin; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 79, 218, 222
44 Folinic acid [1] Leucovorin[2] Folinic acid; Leucovorin; --[4] 19, 46, 107, 320
45 Folinic acid calcium salt pentahydrate [1] Leucovorin[2] Folinic acid; Leucovorin; --[4] 19, 46, 107, 320
46 Formoterol [1] Formoterol[2] Formoterol; Symbicort; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 85, 228, 299
47 Ferric carboxymaltose [1] Ferric carboxymaltose[1] FERRIC CARBOXYMALTOSE; --[4] 86, 96, 97, 299
48 Ferric sulfate [1] Ferric sulfate[1] Stasis; --[2] 66, 97
49 Fostamatinib [1] Fostamatinib[1] Fostamatinib; [1] SYK 💬[17] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease - COVID-19, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬[4] 46, 49, 61, 66
50 Fresolimumab [1] Fresolimumab[2] Fresolimumab; GC1008; [3] TGFB1,
TGFB2,
TGFB3 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Dilated cardiomyopathy, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[3] 51, 85, 222
51 Forigerimod [1] Forigerimod[1] Forigerimod; --[1] 49
52 Fingolimod [1] Fingolimod[3] Fingolimod; FINGOLIMOD HYDROCHLORIDE; Gilenya; [1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 14, 156
53 Ferric maltol [1] Ferric maltol[1] Ferric Maltol; --[1] 96
54 Filgotinib [1] Filgotinib[2] FILGOTINIB; Jyseleca; [1] JAK1 💬[27] Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[6] 46, 53, 96, 97, 222, 271
55 Fremanezumab [1] Fremanezumab[1] Fremanezumab; [1] CALCA 💬[2] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[2] 124, 226
56 Flortaucipir F 18 [1] Flortaucipir[1] Flortaucipir; [1] MAPT 💬[4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[3] 5, 7, 127
57 Fexinidazole [1] Fexinidazole[1] Fexinidazole; --[1] 65
58 Fenebrutinib [1] Fenebrutinib[1] FENEBRUTINIB; [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 13
59 Fletikumab [1] Fletikumab[1] Anti-IL-20; [1] IL20 💬[3] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
60 Foslevodopa [1] Foslevodopa[1] Foslevodopa; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
61 Foscarbidopa [1] Foscarbidopa[1] Foscarbidopa; --[1] 6