93. 原発性胆汁性胆管炎 Primary biliary cholangitis Clinical trials / Disease details
臨床試験数 : 298 / 薬物数 : 252 - (DrugBank : 59) / 標的遺伝子数 : 35 - 標的パスウェイ数 : 115
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ChiCTR2000040593 | 2020-12-01 | 2020-12-03 | Prevalence and prognostic risk of primary biliary cholangitis in Yunnan Province | Prevalence and prognostic risk of primary biliary cholangitis in Yunnan Province | primary biliary cholangitis | Gold Standard:PBC can be diagnosed by meeting 2 of the following 3 criteria :(1) serum biochemical indication of increased ALP;(2) When AMA is positive or AMA is negative, other PBC specific autoantibodies, such as SP100 and GP210 are positive;(3) Histological evidence suggested non-suppurative destructive cholangitis and inter-lobu;Index test:AMA in serum of suspected PBC cases was detected by traditional AMA-M2 test and BPO test, respectively.; | The Second Affiliated Hospital of Kunming Medical University | NULL | Pending | Male | Target condition:0;Difficult condition:0 | N/A | China | ||
| 2 | ChiCTR2000032053 | 2020-05-01 | 2020-04-19 | Application value of ultrasonography combined with transient elastography for staging of hepatic fibrosis in patients with primary biliary cholangitis (PBC) | Application value of ultrasonography combined with transient elastography for staging of hepatic fibrosis in patients with primary biliary cholangitis (PBC) | primary biliary cholangitis | Gold Standard:Any two of the following items met: 1. increased biochemical indicators of cholestasis such as alkaline phosphatase; 2. positive serum AMA or AMA-M2; 3. hepatic histopathology.;Index test:high-frequency and low-frequency ultrasound?transient elastography (TE); | You'an Hospital, Capital Medical University | NULL | Pending | 18 | 70 | Both | Target condition:100;Difficult condition:270 | N/A | China |
| 3 | ChiCTR1900024836 | 2019-07-30 | 2019-07-30 | Exploration of non-invasive diagnostic model of liver fibrosis based on artificial intelligence in primary biliary cholangitis Clinical research protocol | Exploration of non-invasive diagnostic model of liver fibrosis based on artificial intelligence in primary biliary cholangitis Clinical research protocol | Primary biliary cholangitis | Gold Standard:Liver biopsy pathology.;Index test:Non-invasive diagnostic model for liver fibrosis: including AST/PLT value index (APRI model), Forns model, S index, and based on this, a new non-invasive liver fibrosis diagnosis model is generated.; | Beijing You'an Hospital, Capital Medical University | NULL | Recruiting | 18 | 80 | Both | Target condition:180;Difficult condition:180 | China |