96. クローン病 Crohn disease Clinical trials / Disease details


臨床試験数 : 2,442 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209

  
22 trials found
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1NCT05606419
(ClinicalTrials.gov)
January 202324/10/2022The Crohn's Disease Exclusion Diet With Early Dairy Introduction Plus Partial Enteral Nutrition for Crohn's DiseaseThe Crohn's Disease Exclusion Diet With Early Dairy Introduction Plus Partial Enteral Nutrition (CD-EDEN) in Adult Patients With Crohn's DiseaseCrohn DiseaseDietary Supplement: CDED+PEN+dairy products;Dietary Supplement: PEN+usual careEvangelismos HospitalAgricultural University of AthensNot yet recruiting18 YearsN/AAll120N/ANULL
2ChiCTR2200058343
2022-04-132022-04-07To investigate the effect of pancreatin on diarrhea of crohn's disease patients taking total enteral nutritionTo investigate the effect of pancreatin on diarrhea of crohn's disease patients taking total enteral nutrition Crohn's diseaseExperimental group:Take trypsin medications;Renmin Hospital of Wuhan UniversityNULLPending1875BothExperimental group:53;Phase 4China
3ChiCTR2200058055
2022-04-012022-03-27A prospective, multicenter observational study of adalimumab biological analogues combined with partial enteral nutrition in the evaluation of the efficacy of Crohn's diseaseA prospective, multicenter observational study of adalimumab biological analogues combined with partial enteral nutrition in the evaluation of the efficacy of Crohn's disease Inflammatory bowel disease (IBD)Hemienteral nutrition group:adalimumab biological analogues combined with partial enteral nutrition therapy;Internal nutrition group:adalimumab combined with total enteral nutrition;The adamumab group:adalimumab;The First Affiliated Hospital of Shantou University Medical CollegeNULLPending1875BothHemienteral nutrition group:30;Internal nutrition group:30;The adamumab group:60;N/AChina
4NCT04859088
(ClinicalTrials.gov)
September 20, 202115/4/2021Biologics and Partial Enteral Nutrition StudyCombining Partial Enteral Nutrition With Biologics to Optimise Induction and Maintenance Therapy for Adults With Active Ileocolonic Crohn's DiseaseCrohn DiseaseDietary Supplement: Partial Enteral NutritionNHS Greater Glasgow and ClydeUniversity of GlasgowRecruiting16 YearsN/AAll80N/AUnited Kingdom
5NCT04921033
(ClinicalTrials.gov)
March 1, 20214/6/2021Exclusive Enteral Nutrition in Patients With Ileocaecal Crohn's DiseaseExclusive Enteral Nutrition in Patients With Ileocaecal Crohn's Disease (XENIC): an Open-label, Multicenter, Prospective, Randomized Clinical TrialCrohn Disease;Nutrient; Excess;Remission/RegressionDietary Supplement: EEN (Nestle Modulen®);Drug: Standart of careDuzce UniversityNULLRecruiting18 Years75 YearsAll256Phase 3Turkey
6NCT04398836
(ClinicalTrials.gov)
September 202018/7/2019Preoperative Nutrition for Crohn's Disease PatientsPreoperative Nutrition for Crohn's Disease PatientsMalnutrition;Crohn DiseaseDietary Supplement: Exclusive Enteral Nutrition;Other: High energy / protein diet.;Other: Standard nutritionTel-Aviv Sourasky Medical CenterNULLNot yet recruiting18 Years70 YearsAll144Phase 3Israel
7NCT05321758
(ClinicalTrials.gov)
March 22, 20204/4/2022Fecal Microbiota Transplantation as the First-line Treatment in Active Pediatric Crohn's DiseaseRepeated and Multiple Fecal Microbiota Transplantations Plus Partial Enteral Nutrition as the First-line Treatment in Active Pediatric Crohn's DiseaseCrohn DiseaseBiological: Fecal Microbiota Transplantation;Other: PENTongji HospitalNULLRecruiting2 Years16 YearsAll50N/AChina
8NCT03833596
(ClinicalTrials.gov)
October 25, 201821/12/2018Exclusive Enteral Nutrition and Corticosteroids Therapy in Crohn's Disease (EENCD)Synergistic Effect of Exclusive Enteral Nutrition Formula in Addition to Corticosteroids Therapy to Induce Clinical Remission in Patients With Crohn's Disease: a Pilot Study Involving a Multidimensional Assessment of Potential MechanismsCrohn's DiseaseDrug: Prednisone;Dietary Supplement: Exclusive Enteral NutritionMcMaster UniversityNestléTerminated18 Years75 YearsAll3Phase 4Canada
9NCT04160325
(ClinicalTrials.gov)
May 14, 20183/11/2019Effect of the Exclusive Enteral Nutrition Combined With Azathioprine for Remission of Crohn's Diseases After SurgeryThe Effect of the Exclusive Enteral Nutrition Combined With Azathioprine in Maintaining Remission of Patients With Crohn's Diseases After SurgeryCrohn DiseaseDietary Supplement: postoperative 3-month exclusive enteral nutrition;Drug: azathioprine;Other: normal dietZhu WeimingSixth Affiliated Hospital, Sun Yat-sen University;Sir Run Run Shaw Hospital;The First Affiliated Hospital of Anhui Medical University;Beijing Tsinghua Changgung HospitalRecruiting18 Years65 YearsAll198N/AChina
10NCT03755583
(ClinicalTrials.gov)
February 1, 201718/11/2018Effect of Exclusive Enteral Nutrition on Disease Process, Nutritional Status and Gastrointestinal Microbiota for Chinese Children With Crohn's DiseaseEffect of Exclusive Enteral Nutrition on Disease Process, Nutritional Status and Intestinal Microbiota for Chinese Children With Crohn's DiseaseCrohn Disease;Enteral Nutrition;Gastrointestinal MicrobiomeDietary Supplement: Exclusive Enteral NutritionChildren's Hospital of Fudan UniversityNULLCompleted1 Year17 YearsAll31N/AChina
11NCT02231814
(ClinicalTrials.gov)
December 201627/8/2014The Crohn's Disease Exclusion Diet With Partial Enteral Nutrition or Alone in Adult Patients With Crohn's DiseaseDietary Therapy Using the Crohn's Disease Exclusion Diet (CDED) With Partial Enteral Nutrition or Alone for Induction and Maintenance of Remission in in Adults With Mild to Moderate Crohn's Disease- A Pilot StudyCrohn's DiseaseDietary Supplement: Crohns Disease Exclusion Diet + PEN;Other: Crohns Disease Exclusion DietProf. Arie LevineNULLCompleted18 Years55 YearsAll40N/AIsrael
12NCT02998827
(ClinicalTrials.gov)
November 201624/11/2016Thalidomide Results in Diminished Ovarian Reserve in Reproductive Age Female IBD PatientsCrohn DiseaseDrug: Thalidomide;Drug: infliximab, azathioprine;Other: enteral nutritionSixth Affiliated Hospital, Sun Yat-sen UniversityNULLEnrolling by invitationN/AN/AFemale90N/ANULL
13NCT02897661
(ClinicalTrials.gov)
August 201614/8/2016Washed Microbiota Transplantation Improves Nutritional Status of Patients With Crohn's DiseaseWashed Microbiota Transplantation Combining Exclusive Enteral Nutrition Contribute to Nutritional Improvement of Patients With Crohns' DiseaseCrohn's DiseasesProcedure: WMT;Dietary Supplement: EENThe Second Hospital of Nanjing Medical UniversityNULLRecruiting18 Years65 YearsAll30N/AChina
14NCT02517684
(ClinicalTrials.gov)
April 20151/7/2015Top-down Infliximab Study in Kids With Crohn's DiseaseTop-down Infliximab Study in Kids With Crohn's DiseaseCrohn's DiseaseDrug: Infliximab;Drug: Prednisolone;Other: Exclusive enteral nutrition;Drug: AzathioprineErasmus Medical CenterZonMw: The Netherlands Organisation for Health Research and Development;Hospira, now a wholly owned subsidiary of PfizerActive, not recruiting3 Years17 YearsAll100Phase 4Belgium;Finland;Netherlands;Denmark;Italy;Poland
15NCT02201693
(ClinicalTrials.gov)
December 12, 201417/7/2014Cyclic Exclusive Enteral Nutrition as Maintenance Therapy for Pediatric Crohn's DiseaseRandomised Trial Comparing 12 Months of Cyclic Enteral Nutrition to Supplementary Enteral Nutrition as Maintenance Therapy for Pediatric Crohn's DiseaseCrohn's DiseaseDietary Supplement: MODULEN IBDAssistance Publique - Hôpitaux de ParisGETAID PediatricCompleted6 Years18 YearsAll100N/AFrance
16NCT02056418
(ClinicalTrials.gov)
January 201424/1/2014Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in AdultA Randomized, Controlled, Single-blind Study of Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in AdultCrohn DiseaseDietary Supplement: enteral nutrition;Drug: corticosteroidJinling Hospital, ChinaNULLActive, not recruiting18 Years75 YearsBoth30Phase 4China
17NCT02887287
(ClinicalTrials.gov)
July 201329/8/2016Efficacy of Exclusive Enteral Nutrition in Adult Active Crohn's DiseaseEfficacy of Exclusive Enteral Nutrition in Adult Active Crohn's Disease With Complications or Failure of Medical TreatmentDrug: EENSun Yat-sen UniversityNULLCompleted18 Years60 YearsBoth48N/AChina
18NCT02233062
(ClinicalTrials.gov)
May 20131/9/2014Impact of Exclusive Enteral Nutrition Therapy on Sperm Quality of Patients With Crohn's DiseaseImpact of Exclusive Enteral Nutrition Therapy on Sperm Quality of Male Patients With Crohn's DiseaseCrohn's DiseaseDietary Supplement: Exclusive Enteral Nutrition TherapyJinling Hospital, ChinaNULLCompleted18 Years40 YearsMale12N/AChina
19NCT01820247
(ClinicalTrials.gov)
December 201225/3/2013Efficacy Study of Tripterygium Glycoside Combined With Enteral Nutrition in the Treatment of Crohn's Disease for Induction RemissionEfficacy Study of Tripterygium Glycoside Combined With Enteral Nutrition in the Treatment of Crohn's Disease for Induction RemissionCrohn's DiseaseDrug: enteral nutrition;Drug: Tripterygium glycosidesZhu WeimingNULLRecruiting18 Years75 YearsBoth100N/AChina
20NCT01823029
(ClinicalTrials.gov)
November 201225/3/2013Oxidative Stress and Inflammation Caused by Intravenous Iron in Crohn's Disease Patients With Iron Deficiency AnemiaCrohn's DiseaseDrug: erythropoietin;Drug: enteral nutrition.;Drug: injection of ironJinling Hospital, ChinaMinistry of Health, ChinaCompleted18 Years75 YearsBoth387N/AChina
21NCT01823042
(ClinicalTrials.gov)
October 201225/3/2013The Efficacy of Enteral Nutrition in Fill of the Treatment Blank Period of the Postoperative Maintain Remission Medication for Crohn's Disease (CD)A Randomized, Controlled, Open-label Study to Assess the the Efficacy of Enteral Nutrition in Fill of the Treatment Blank Period of the Postoperative Maintain Remission Medication for Crohn's Disease (CD).Crohn's DiseaseDrug: azathioprine+enteral nutrition;Drug: AzathioprineJinling Hospital, ChinaNULLRecruiting18 Years75 YearsBoth100N/AChina
22NCT00265772
(ClinicalTrials.gov)
November 200514/12/2005Comparison of a Nutritional Anti-Inflammatory Treatment to Steroids for Pediatric Crohn's Disease - the Molecular BasisPhase IV Study Comparing a Nutritional Anti-Inflammatory Treatment to Steroids for Pediatric Crohn's Disease - the Molecular BasisCrohn's Disease;PediatricDrug: MODULEN IBD (R) (specific Enteral Nutrition);Drug: prednisolonHôpital Necker-Enfants MaladesInstitut National de la Santé Et de la Recherche Médicale, France;NestléRecruiting6 Years18 YearsBoth24Phase 4France