96. クローン病 Crohn disease Clinical trials / Disease details


臨床試験数 : 2,442 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209

  
5 trials found
No.TrialIDDate_
enrollment
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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PhaseCountries
1EUCTR2014-001295-65-IT
(EUCTR)
01/12/201427/11/2014Phase II study evaluating Ovasave, a cell therapy, in patient with active Crohn's DiseaseA phase IIb, multicentre, randomised, double-blinded (DB), placebo-controlled, multi-dose and multi-injection, parallel groups study to evaluate the efficacy and the safety of Ovasave (ovalbumin-specific autologous Treg cells (ova-Treg)) in patients with active refractory Crohn’s Disease (Crohn’s And Treg Study: CATS29) - CATS29 Moderately to severely active Crohn's Disease
MedDRA version: 17.1;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: Ovasave
INN or Proposed INN: Ova-Treg
Other descriptive name: Autologous ovalbumin-specific type 1 regulatory T lymphocytes expanded population
Product Name: Ovasave
INN or Proposed INN: Ova-Treg
Other descriptive name: Autologous ovalbumin-specific type 1 regulatory T lymphocytes expanded population
Product Name: Ovasave
INN or Proposed INN: Ova-Treg
Other descriptive name: Autologous ovalbumin-specific type 1 regulatory T lymphocytes expanded population
TxCellNULLNot RecruitingFemale: yes
Male: yes
200Phase 2Belgium;Austria;Germany;Italy
2EUCTR2014-001295-65-AT
(EUCTR)
01/12/201419/11/2014Phase II study evaluating Ovasave, a cell therapy, in patient with active Crohn's DiseaseA phase IIb, multicentre, randomised, double-blinded (DB), placebo-controlled, single-dose and multi-injection, parallel groups study to evaluate the efficacy and the safety of Ovasave (ovalbumin-specific autologous Treg cells (ova-Treg)) in patients with active refractory Crohn’s Disease (Crohn’s And Treg Study: CATS29) - CATS29 Moderately to severely active Crohn's Disease
MedDRA version: 18.1;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: Ovasave
INN or Proposed INN: Ova-Treg
Other descriptive name: Autologous ovalbumin-specific type 1 regulatory T lymphocytes expanded population
TxCellNULLNot RecruitingFemale: yes
Male: yes
170Phase 2Belgium;Austria;Germany;Italy
3NCT02327221
(ClinicalTrials.gov)
December 201423/12/2014Study Evaluating Ovasave, an Autologous Cell Therapy, in Patients With Active Crohn's DiseaseA Phase IIb, Multicentre, Randomised, Double-blinded, Placebo-controlled, Multi-dose and Multi-injection, Parallel Groups Study to Evaluate the Efficacy and the Safety of Ovasave in Patients With Active Refractory Crohn's DiseaseCrohn DiseaseDrug: Ovasave;Drug: PlaceboTxCellNULLTerminated18 Years70 YearsAll32Phase 2Austria;Belgium;France;Germany;Italy;United Kingdom
4EUCTR2014-001295-65-BE
(EUCTR)
28/11/201417/11/2014Phase II study evaluating Ovasave, a cell therapy, in patient with active Crohn's DiseaseA phase IIb, multicentre, randomised, double-blinded (DB), placebo-controlled, single-dose and parallel-group study to evaluate the efficacy and the safety of Ovasave (ovalbumin-specific autologous Treg cells (Ova-Treg)) in patients with active refractory Crohn's Disease (Crohn's And Treg Study: CATS29) - CATS29 Moderately to severely active Crohn's Disease
MedDRA version: 19.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: Ovasave
INN or Proposed INN: Ova-Treg
Other descriptive name: Autologous ovalbumin-specific type 1 regulatory T lymphocytes expanded population
TxCellNULLNot RecruitingFemale: yes
Male: yes
117Phase 2Belgium;Austria;Germany;Italy
5EUCTR2014-001295-65-DE
(EUCTR)
25/11/201419/11/2014Phase II study evaluating Ovasave, a cell therapy, in patient with active Crohn's DiseaseA phase IIb, multicentre, randomised, double-blinded (DB), placebo-controlled, single-dose and multi-injection, parallel groups study to evaluate the efficacy and the safety of Ovasave (ovalbumin-specific autologous Treg cells (ova-Treg)) in patients with active refractory Crohn’s Disease (Crohn’s And Treg Study: CATS29) - CATS29 Moderately to severely active Crohn's Disease
MedDRA version: 18.1;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: Ovasave
INN or Proposed INN: Ova-Treg
Other descriptive name: Autologous ovalbumin-specific type 1 regulatory T lymphocytes expanded population
TxCellNULLNot RecruitingFemale: yes
Male: yes
170Phase 2Belgium;Austria;Germany;Italy