215. Tetralogy of Fallot Clinical trials / Disease details
Clinical trials : 18 / Drugs : 26 - (DrugBank : 14) / Drug target genes : 13 - Drug target pathways : 45
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05579964 (ClinicalTrials.gov) | October 10, 2022 | 11/10/2022 | The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot | The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot | Congenital Heart Disease in Children;Cardiopulmonary Bypass;Tetralogy of Fallot | Drug: Dexmedetomidine Hcl 100 Mcg/mL Inj;Drug: Placebo | National Cardiovascular Center Harapan Kita Hospital Indonesia | NULL | Recruiting | 1 Month | 18 Years | All | 66 | Phase 2/Phase 3 | Indonesia |
| 2 | ChiCTR2000033234 | 2020-06-05 | 2020-05-25 | Comprehensive study for surgical effect and prognosis of Tetralogy of Fallot | A single-center ambispective cohort study for surgical effect and prognostic factors of Tetralogy of Fallot after surgical repair | Tetralogy of Fallot | TOF AS:annlus-sparing repair;TOF TAPE:transannular patch enlargement; | Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College | NULL | Pending | Both | TOF AS:247;TOF TAPE:247; | N/A | China | ||
| 3 | EUCTR2013-002091-41-NL (EUCTR) | 09/10/2014 | 05/11/2013 | Research into the effect of the drug losartan in adult patients with a reduced function of the right cardiac chamber and a cardiac birth defect | Right vEntricular Dysfunction in tEtralogy of Fallot: INhibition of the rEnin-angiotensin-aldosterone system - Redefine trial | To study the effect of losartan in adult patients with Tetralogy of Fallot and right ventricular dysfunction, defined as right ventricular ejection fraction <50%. Without severe valvular lesions.;Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14] | Trade Name: Losartan Product Name: Losartan INN or Proposed INN: Losartan Potassium Other descriptive name: LOSARTAN POTASSIUM | Academisch medisch centrum | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | Netherlands | ||||
| 4 | EUCTR2007-003461-41-DE (EUCTR) | 13/11/2007 | 10/09/2007 | Cardiac imaging under dobutamine stress for early assessment of right ventricular function in patients with tetralogy of Fallot and pulmonary regurgitation - Fallot-stress | Cardiac imaging under dobutamine stress for early assessment of right ventricular function in patients with tetralogy of Fallot and pulmonary regurgitation - Fallot-stress | Fallot tetralogy late after repair with marked pulmonary valve incompetence | INN or Proposed INN: Dobutamine | Deutsche Herzzentrum Berlin, Kompetenznetz Angeborene Herzfehler | NULL | Not Recruiting | Female: yes Male: yes | 80 | Germany | |||
| 5 | NCT00564993 (ClinicalTrials.gov) | November 2007 | 28/11/2007 | Cardiac Function Under Stress for Early Detection of the Right Ventricular Insufficiency After Repair of Tetralogy of Fallot | Cardiac Imaging Under Exercise Stress Test for Early Assessment of Right Ventricular Function in Patients With Tetralogy of Fallot and Pulmonary Regurgitation | Tetralogy of Fallot | Drug: Dobutamin | Competence Network for Congenital Heart Defects | German Federal Ministry of Education and Research | Terminated | 14 Years | N/A | Both | 53 | Phase 3 | Germany |