Butyrate ( DrugBank: Butyrate )

4 diseases

46. 悪性関節リウマチ

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05718583 (ClinicalTrials.gov)	February 1, 2023	30/1/2023	Effects of Administration of SCFA in Rheumatoid Arthritis Inadequate Responders	A Pilot Proof of Concept Study of the Effects of Administration of a Short Chain Fatty Acid (SCFA) Supplement in Rheumatoid Arthritis Inadequate Responders (EASi-RAIR)	Rheumatoid Arthritis	Dietary Supplement: Butyrate	NYU Langone Health	Arthritis Foundation	Recruiting	18 Years	N/A	All	35	N/A	United States
2	NCT05576597 (ClinicalTrials.gov)	August 23, 2022	7/10/2022	Effect of Butyrate Supplement on Rheumatoid Arthritis	A Pilot Study to Evaluate Efficacy and Safety of Butyrate Supplement in the Treatment of Rheumatoid Arthritis	Rheumatoid Arthritis	Drug: Sodium Butyrate	Peking University People's Hospital	NULL	Recruiting	18 Years	N/A	All	30	Phase 2	China

臨床試験数 : 2,630 / 薬物数 : 1,459 - (DrugBank : 265) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05218850 (ClinicalTrials.gov)	July 1, 2022	20/1/2022	The Use of Butyrate Therapy in Pediatric Ulcerative Colitis	Butyrate Therapy in Pediatric Ulcerative Colitis	Ulcerative Colitis	Drug: Butyrate	Children's Hospital Los Angeles	NULL	Not yet recruiting	7 Years	21 Years	All	10	Phase 1	United States
2	NCT04259060 (ClinicalTrials.gov)	June 2020	27/1/2020	Hydroxocobalamin Approach to Reduction of Calprotectin With Butyrate for Ulcerative Colitis Research	Hydroxocobalamin Approach to Reduction of Nitrite With Butyrate for Ulcerative Colitis	Ulcerative Colitis	Drug: Hydroxocobalamin with Butyrate;Drug: Placebo with Butyrate	Joshua Korzenik	NULL	Not yet recruiting	18 Years	75 Years	All	42	Phase 2	United States

臨床試験数 : 44 / 薬物数 : 61 - (DrugBank : 23) / 標的遺伝子数 : 57 - 標的パスウェイ数 : 83

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05420805 (ClinicalTrials.gov)	April 1, 2022	13/6/2022	Protective Role of Pre-/ Post-biotics on Gut Inflammation, Dysbiosis, and Life Quality in Rett Syndrome (Biotics_RTT)	Protective Effects of Pre- and Post-biotics on Gut Inflammation, Microbiota Diversity, Epileptogenesis, and Quality of Life in Rett Syndrome	Rett Syndrome;Dysbiosis;Epilepsy;Quality of Life	Dietary Supplement: ALAC, inulin, FOS, and sodium butyrate;Dietary Supplement: Sodium butyrate and zinc oxide	Azienda Ospedaliera Universitaria Senese	Kolfarma s.r.l. - Italy;European Institute of Oncology	Recruiting	3 Years	N/A	Female	30	N/A	Italy

臨床試験数 : 12 / 薬物数 : 24 - (DrugBank : 15) / 標的遺伝子数 : 0 - 標的パスウェイ数 : 0

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03660176 (ClinicalTrials.gov)	January 2, 2019	4/9/2018	Effects of Butyrate Enemas on Postoperative Intestinal Mobility Disorders in Hirschsprung's Disease	Effects of Butyrate Enemas on Postoperative Intestinal Mobility Disorders in Hirschsprung's	Hirschsprung's Disease	Drug: butyrate enemas + routine management;Other: routine management	Assistance Publique Hopitaux De Marseille	NULL	Not yet recruiting	N/A	17 Years	All	58	Phase 3	France