Cortef ( DrugBank: - )

3 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
6	パーキンソン病	1
81	先天性副腎皮質酵素欠損症	5
83	アジソン病	6

6. パーキンソン病

臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2014-000657-36-NL (EUCTR)	22/06/2015	03/06/2015	Trial to investigate the efficacy of treatments in apomorphine-induced skin reactions	Open-label crossover trial to investigate the efficacy of treatments in apomorphine-induced skin rea ...	Parkinson's disease;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Trade Name: Hydrocortisone cream 10mg/g FNA Fagron Product Name: Hydrocortisone cream Trade Name: Solu ...	University Medical Center Groningen	NULL	Not Recruiting			Female: yes Male: yes	20	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	Netherlands

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81. 先天性副腎皮質酵素欠損症

臨床試験数 : 87 / 薬物数 : 87 - (DrugBank : 23) / 標的遺伝子数 : 12 - 標的パスウェイ数 : 68

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05063994 (ClinicalTrials.gov)	December 13, 2021	28/5/2021	Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 ...	A Randomized, Double-Blind, Active-Controlled, Phase 3 Study of Chronocort Compared With Immediate-R ...	Congenital Adrenal Hyperplasia	Drug: Chronocort;Drug: Cortef	Diurnal Limited	NULL	Recruiting	16 Years	N/A	All	150	Phase 3	United States;France;Japan
2	EUCTR2011-005822-23-SE (EUCTR)	18/11/2014	20/09/2013	A trial comparing continuous subcutaneous hydrocortisone infusion (CSHI) therapy with conventional o ...	CONTINUOUS SUBCUTANEOUS HYDROCORTISONE INFUSION IN CONGENITAL ADRENAL HYPERPLASIA	Congenital Adrenal Hyperplasia MedDRA version: 14.1;Level: LLT;Classification code 10010323;Term: Co ...	Trade Name: Solu-Cortef INN or Proposed INN: HYDROCORTISONE SODIUM SUCCINATE Other descriptive name: H ...	Haukeland University Hospital	NULL	Not Recruiting			Female: yes Male: yes	20	Phase 2	Norway;Sweden
3	NCT02096510 (ClinicalTrials.gov)	August 2014	28/11/2013	Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia ...	Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia ...	Addison Disease;Adrenal Hyperplasia Congenital	Drug: Solu-Cortef;Drug: Cortef	Haukeland University Hospital	NULL	Recruiting	18 Years	65 Years	Both	10	Phase 1/Phase 2	Norway
4	EUCTR2011-005822-23-NO (EUCTR)	16/10/2012	25/02/2013	A trial comparing continuous subcutaneous hydrocortisone therapy with conventional oral glucocortico ...	CONTINUOUS SUBCUTANEOUS HYDROCORTISONE INFUSION IN CONGENITAL ADRENAL HYPERPLASIA	Congenital adrenal hyperplasia (CAH) MedDRA version: 14.1;Level: LLT;Classification code 10010323;Te ...	Trade Name: Solu-Cortef Trade Name: Cortison Trade Name: Prednisolone	Haukeland University Hospital	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Norway
5	NCT00519818 (ClinicalTrials.gov)	August 2007	22/8/2007	Comparison of Two Forms of Hydrocortisone in Patients With Congenital Adrenal Hyperplasia	A Phase 2, Open Label, Crossover Pharmacokinetic and Pharmacodynamic Study to Compare Chronocort Ver ...	Congenital Adrenal Hyperplasia;21-Hydroxylase Deficiency;Adrenogenital Syndrome	Drug: Chronocort;Drug: Cortef	Diurnal Limited	National Institutes of Health Clinical Center (CC)	Completed	16 Years	60 Years	All	20	Phase 1/Phase 2	United States

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83. アジソン病

臨床試験数 : 20 / 薬物数 : 39 - (DrugBank : 13) / 標的遺伝子数 : 6 - 標的パスウェイ数 : 18

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05350020 (ClinicalTrials.gov)	March 14, 2022	29/3/2022	The Effects of Two Brands of Hydrocortisone Injected Intramuscularly Into Deltoid and Thigh Muscles	An Open Label Pilot Study to Investigate the Effects of Two Preparations of Hydrocortisone (Hydrocor ...	Addison's Disease	Drug: Solu-Cortef 100 MG Injection;Drug: Hydrocortisone 100mg/ml	The London Clinic	NULL	Recruiting	18 Years	70 Years	All	8	Phase 4	United Kingdom
2	EUCTR2015-001090-40-GB (EUCTR)	22/06/2015	08/04/2015	The effects of two brands of hydrocortisone injected intramuscularly into deltoid and thigh muscles	An open label pilot study to investigate the effects of two preparations of hydrocortisone (Hydrocor ...	Addison's Disease MedDRA version: 20.1;Level: PT;Classification code 10001130;Term: Addison's diseas ...	Trade Name: Solu-Cortef Product Name: Solu-Cortef INN or Proposed INN: Hydrocortisone Trade Name: Hydro ...	The London Clinic	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	8	Phase 4	United Kingdom
3	NCT02096510 (ClinicalTrials.gov)	August 2014	28/11/2013	Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia ...	Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia ...	Addison Disease;Adrenal Hyperplasia Congenital	Drug: Solu-Cortef;Drug: Cortef	Haukeland University Hospital	NULL	Recruiting	18 Years	65 Years	Both	10	Phase 1/Phase 2	Norway
4	EUCTR2013-004189-33-NO (EUCTR)	28/11/2013	30/10/2013	A trial comparing continuous subcutaneous hydrocortisone therapy with pulsatile subcutaneous hydroco ...	ULTRADIAN SUBCUTANEOUS HYDROCORTISONE (USHI) INFUSION IN ADDISON’S DISEASE	Addison`s disease;Therapeutic area: Diseases [C] - Hormonal diseases [C19]	Trade Name: Solu-Cortef Trade Name: Cortef 5 mg	Haukeland University Hospital	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	10		Norway
5	EUCTR2009-010917-61-SE (EUCTR)	25/08/2010	05/07/2010	Glucocorticoid Replacement in Addison's disease	Glucocorticoid Replacement in Addison's disease	Autoimmune Addison's disease is a rare and chronic disease wich leads to primary adrenal failure. Th ...	Trade Name: Solu-Cortef INN or Proposed INN: HYDROCORTISONE SODIUM SUCCINATE Product Name: Hydrokortis ...	Haukeland University hospital	NULL	Not Recruiting			Female: yes Male: yes	40		Sweden
6	NCT01063569 (ClinicalTrials.gov)	February 2010	26/1/2010	Glucocorticoid Treatment in Addison's Disease	Glucocorticoid Treatment in Addison's Disease	Addison's Disease	Drug: Solu-Cortef (hydrocortisone);Drug: Cortef (hydrocortisone)	Haukeland University Hospital	NULL	Completed	18 Years	70 Years	Both	33	Phase 2/Phase 3	Norway;Sweden

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