Povetacicept ( DrugBank: - )


3 diseases
告示番号疾患名(ページ内リンク)臨床試験数
61自己免疫性溶血性貧血1
63特発性血小板減少性紫斑病1
222一次性ネフローゼ症候群1

61. 自己免疫性溶血性貧血


臨床試験数 : 146 薬物数 : 131 - (DrugBank : 59) / 標的遺伝子数 : 28 - 標的パスウェイ数 : 158
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT05757570
(ClinicalTrials.gov)
May 202324/2/2023An Open-label Study of Povetacicept in Subjects With Autoimmune CytopeniasA Phase 1b Open-Label Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Povetacicept in Subjects With Autoimmune Cytopenias (RUBY-4)Immune Thrombocytopenia;Idiopathic Thrombocytopenic Purpura;Warm Autoimmune Hemolytic Anemia;Cold Agglutinin DiseaseDrug: povetaciceptAlpine Immune Sciences, Inc.NULLNot yet recruiting18 YearsN/AAll42Phase 1NULL

63. 特発性血小板減少性紫斑病


臨床試験数 : 391 薬物数 : 235 - (DrugBank : 50) / 標的遺伝子数 : 49 - 標的パスウェイ数 : 139
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT05757570
(ClinicalTrials.gov)
May 202324/2/2023An Open-label Study of Povetacicept in Subjects With Autoimmune CytopeniasA Phase 1b Open-Label Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Povetacicept in Subjects With Autoimmune Cytopenias (RUBY-4)Immune Thrombocytopenia;Idiopathic Thrombocytopenic Purpura;Warm Autoimmune Hemolytic Anemia;Cold Agglutinin DiseaseDrug: povetaciceptAlpine Immune Sciences, Inc.NULLNot yet recruiting18 YearsN/AAll42Phase 1NULL

222. 一次性ネフローゼ症候群


臨床試験数 : 310 薬物数 : 295 - (DrugBank : 117) / 標的遺伝子数 : 63 - 標的パスウェイ数 : 194
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT05732402
(ClinicalTrials.gov)
March 20238/2/2023An Open-label Study of Povetacicept (ALPN-303) in Autoimmune Kidney DiseasesAn Open-Label, Multiple-Ascending Dose Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Different Dose Levels of Povetacicept in Subjects With Autoantibody-Associated Glomerular Diseases (RUBY-3)Lupus Nephritis;Immunoglobulin A Nephropathy;Membranous NephropathyDrug: povetaciceptAlpine Immune Sciences, Inc.NULLNot yet recruiting18 YearsN/AAll42Phase 1NULL