Acalabrutinib ( DrugBank: Acalabrutinib )


2 diseases
IDDisease name (Link within this page)Number of trials
46Malignant rheumatoid arthritis1
61Autoimmune hemolytic anemia1

46. Malignant rheumatoid arthritis


Clinical trials : 4,356 Drugs : 2,567 - (DrugBank : 415) / Drug target genes : 192 - Drug target pathways : 228
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT02387762
(ClinicalTrials.gov)
April 20151/3/2015ACP-196 Versus Placebo in Subjects With Rheumatoid Arthritis on Background MethotrexateA Phase 2a, 4-Week, Double-Blind, Proof-of-Concept Efficacy and Safety Study of ACP-196 Versus Placebo in Subjects With Active Rheumatoid Arthritis on Background MethotrexateRheumatoid ArthritisDrug: acalabrutinib;Drug: PlaceboAcerta Pharma BVNULLCompleted18 Years75 YearsAll31Phase 2United States

61. Autoimmune hemolytic anemia


Clinical trials : 146 Drugs : 131 - (DrugBank : 59) / Drug target genes : 28 - Drug target pathways : 158
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04657094
(ClinicalTrials.gov)
March 16, 20211/12/2020Acalabrutinib for the Treatment of Relapsed or Refractory Autoimmune Hemolytic Anemia in Patients With Chronic Lymphocytic LeukemiaA Phase 2 Trial of Acalabrutinib for the Treatment of Relapsed/Refractory Autoimmune Hemolytic AnemiaAutoimmune Hemolytic Anemia;Chronic Lymphocytic Leukemia;Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma;Warm Antibody Autoimmune Hemolytic AnemiaDrug: AcalabrutinibCity of Hope Medical CenterNational Cancer Institute (NCI)Active, not recruiting18 YearsN/AAll4Phase 2United States