Alprostadil ( DrugBank: Alprostadil )
2 diseases
| ID | Disease name (Link within this page) | Number of trials |
|---|---|---|
| 51 | Scleroderma | 3 |
| 70 | Spinal stenosis | 1 |
51. Scleroderma
Clinical trials : 525 / Drugs : 565 - (DrugBank : 148) / Drug target genes : 114 - Drug target pathways : 217
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ChiCTR2100054434 | 2019-10-01 | 2021-12-17 | Observation of clinical efficacy of Ying-Pi No.1 hand mask cream in the treatment of scleroderma | Observation of clinical efficacy of Ying-Pi No.1 hand mask cream in the treatment of scleroderma | scleroderma | Experimental group:MTX+ Alprostadil injection + Guipiperate maleate injection + Ying-Pi No.1 hand mask cream for external application;Control group:MTX+ Alprostadil injection + Guipiperate maleate injection; | The First Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine | NULL | Completed | 28 | 78 | Both | Experimental group:30;Control group:30; | China | |
| 2 | ITMCTR2100005418 | 2019-10-01 | 2021-12-17 | Observation of clinical efficacy of Ying-Pi No.1 hand mask cream in the treatment of scleroderma | Observation of clinical efficacy of Ying-Pi No.1 hand mask cream in the treatment of scleroderma | scleroderma | Test group:MTX+ Alprostadil injection + Guipiperate maleate injection + Ying-Pi No.1 hand mask cream for external application;Control group:MTX+ Alprostadil injection + Guipiperate maleate injection; | The First Affiliated Hospital of Zhejiang Chinese Medicine University | NULL | Completed | 28 | 78 | Both | Test group:30;Control group:30; | China | |
| 3 | NCT02228850 (ClinicalTrials.gov) | November 2014 | 20/8/2014 | Study of Acute Peripheral Vascular Effects, Safety and Tolerability in Subjects With Raynaud's Phenomenon Secondary to Systemic Sclerosis | A Phase 2a Double-Blind, Randomized, Placebo-Controlled Crossover Trial of the Acute Peripheral Vascular Effects, Safety and Tolerability of Alprostadil Topical Cream in Subjects With Raynaud's Phenomenon Secondary to Systemic Sclerosis (SSc, Scleroderma) | Raynaud's Phenomenon Secondary to Systemic Sclerosis | Drug: Alprostadil;Other: Placebo | NexMed (U.S.A.), Inc. (subsidiary of Apricus Biosciences, Inc.) | NULL | Completed | 18 Years | 79 Years | Both | 35 | Phase 2 | United States |
70. Spinal stenosis
Clinical trials : 95 / Drugs : 169 - (DrugBank : 61) / Drug target genes : 68 - Drug target pathways : 90
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | JPRN-UMIN000005959 | 2010/11/04 | 12/07/2011 | Prospective clinical study of the therapeutic effects of prostaglandin in patients with combined lumbar spinal stenosis and arteriosclerosis obliterans showing intermittent claudication | Prospective clinical study of the therapeutic effects of prostaglandin in patients with combined lumbar spinal stenosis and arteriosclerosis obliterans showing intermittent claudication - Clinical study on therapeutic effects of prostaglandin in patients with combined lumbar spinal stenosis and arteriosclerosis obliterans | Patients with combined lumbar spinal stenosis and arteriosclerosis obliterans | Prostaglandin for injection (alprostadil) group: 60 mcg of prostaglandin for injection is intravenously administered once a week or more. This therapy is repeated 10 times or more. Ripple injection (alprostadil Injection) group: 10 mcg of ripple injection is administered intravenously once a week or more. This treatment is repeated 10 times or more. Conventional treatment group | Tokai University HospitalDepartment of Orthopaedic Surgery | NULL | Complete: follow-up complete | 20years-old | Not applicable | Male and Female | 300 | Not selected | Japan |