ORM-12741 ( DrugBank: ORM-12741 )

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1 disease

ID	Disease name (Link within this page)	Number of trials
51	Scleroderma	2

51. Scleroderma

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Clinical trials : 525 /  Drugs : 565 - (DrugBank : 148) / Drug target genes : 114 - Drug target pathways : 217

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2010-024005-13-GB (EUCTR)	11/03/2011	30/12/2010	A study of ORM-12741 for the prevention of blood vessel spasm brought on by cold temperature.	Efficacy of ORM-12741 for prevention of cold-induced vasospasm; a randomised, double-blind, placebo-controlled, single centre crossover study in patient with Raynaud's phenomenon secondary to systemic sclerosis - Reino	Raynaud's phenomenon secondary to systemic sclerosis (Raynaud's syndrome) MedDRA version: 14.0;Level: LLT;Classification code 10037914;Term: Raynaud's syndrome;System Organ Class: 10047065 - Vascular disorders;Therapeutic area: Diseases [C] - Skin and Connective Tissue Diseases [C17]	Product Name: ORM-12741 Product Code: ORM-12741 Other descriptive name: alpha-2C AR antagonist Product Name: ORM-12741 Product Code: ORM-12741 Other descriptive name: Alpha-2C AR antagonist	Orion Corporation Orion Pharma	NULL	Not Recruiting			Female: yes Male: yes			United Kingdom
2	NCT01315899 (ClinicalTrials.gov)	March 2011	14/3/2011	Efficacy of ORM-12741 for Prevention of Raynaud's Phenomenon	Phase IIa Study of the Efficacy of ORM-12471 for Prevention of Cold-induced Vasospasm: a Randomised, Double-blind, Placebo-controlled, Single Centre Crossover Study in Patients With Raynaud's Phenomenon Secondary to Systemic Sclerosis	Raynaud's Phenomenon	Drug: ORM-12471 30mg;Drug: ORM-12471;Drug: placebo	Orion Corporation, Orion Pharma	NULL	Terminated	18 Years	75 Years	Both	15	Phase 2	United Kingdom