Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Acetylsalicylic acid	Acetylsalicylic acid	[1] D00109 💬	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	[4] 13, 46, 51, 210 💬
2	Act-064992	-	-	-	-	[5] 51, 85, 86, 88, 210 💬
3	Administration of an ace-inhibitor or not	-	-	-	-	[1] 210 💬
4	Aesculus hippocastanum / horse chestnut	Horse chestnut	-	-	-	[1] 210 💬
5	Ambrisentan	Ambrisentan	[1] D07077 💬	[1] EDNRA 💬	[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[7] 51, 84, 85, 86, 88, 210, 211 💬
6	Arginine	Arginine	[1] D02982 💬	-	-	[9] 46, 67, 78, 96, 97, 113, 210, 251, 299 💬
7	Aspirin	Acetylsalicylic acid	[1] D00109 💬	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	[11] 13, 22, 34, 46, 49, 51, 86, 113, 158, 210, 231 💬
8	Autologous tissue-engineered vascular graft	-	-	-	-	[1] 210 💬
9	Bay 59-7939	-	-	-	-	[1] 210 💬
10	Bosentan	Bosentan	[2] D01227, D07538 💬	[2] EDNRA, EDNRB 💬	[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
11	Carvedilol	Carvedilol	[2] D00255, D03415 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	[12] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[5]  6 , 57, 86, 113, 210 💬
12	Colchicine	Colchicine	[1] D00570 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection	[7]  2 , 42, 46, 56, 93, 210, 266 💬
13	Digoxin	Digoxin	[1] D00298 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	[18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway	[3]  8 , 46, 210 💬
14	Enalapril	Enalapril	[2] D00621, D07892 💬	[1] ACE 💬	[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system	[7] 19, 46, 66, 113, 210, 222, 223 💬
15	Eplerenone	Eplerenone	[1] D01115 💬	[1] NR3C2 💬	[1] Aldosterone-regulated sodium reabsorption	[4] 75, 113, 210, 215 💬
16	Horse chestnut	Horse chestnut	-	-	-	[1] 210 💬
17	Jnj-39039039	-	-	-	-	[1] 210 💬
18	Liothyronine	Liothyronine	[2] D01011, D08128 💬	[2] THRA, THRB 💬	[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway	[3] 13, 210, 212 💬
19	Liothyronine i 131	Liothyronine	[2] D01011, D08128 💬	[2] THRA, THRB 💬	[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway	[2] 210, 212 💬
20	Macitentan	Macitentan	[1] D10135 💬	[2] EDNRA, EDNRB 💬	[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	[5] 51, 85, 86, 88, 210 💬
21	Milk	Cow milk	-	-	-	[2] 98, 210 💬
22	Mpc	-	-	-	-	[2] 210, 211 💬
23	Mysildecard	-	-	-	-	[1] 210 💬
24	Mysildecard 20 mg	-	-	-	-	[1] 210 💬
25	Mz101	-	-	-	-	[1] 210 💬
26	Nitric oxide	Nitric Oxide	[1] D00074 💬	-	-	[8] 46, 85, 86, 98, 210, 251, 294, 299 💬
27	Normal saline	-	-	-	-	[16]  6 , 17, 22, 36, 46, 49, 60, 70, 94, 96, 210, 211, 226, 276, 296, 299 💬
28	Odsh at 0.125 mg/kg/h	-	-	-	-	[1] 210 💬
29	Odsh at 0.250 mg/kg/h	-	-	-	-	[1] 210 💬
30	Odsh at 0.375 mg/kg/h	-	-	-	-	[1] 210 💬
31	Opsumit	-	-	-	-	[3] 86, 88, 210 💬
32	Opsumit®	-	-	-	-	[3] 86, 88, 210 💬
33	Other: human milk derived fortifier	Cow milk	-	-	-	[1] 210 💬
34	Other: human/bovine milk	Cow milk	-	-	-	[1] 210 💬
35	Rexlemestrocel-l	-	-	-	-	[2] 210, 211 💬
36	Rivaroxaban	Rivaroxaban	[1] D07086 💬	[1] F10 💬	[1] Complement and coagulation cascades	[5] 46, 49, 75, 91, 210 💬
37	Scrm001_tevg	-	-	-	-	[1] 210 💬
38	Sildenafil	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
39	Sildenafil by injection	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 210 💬
40	Spironolactone	Spironolactone	[1] D00443 💬	[1] NR3C2 💬	[1] Aldosterone-regulated sodium reabsorption	[7] 58, 67, 86, 113, 210, 218, 225 💬
41	Spironolactone (drug)	Spironolactone	[1] D00443 💬	[1] NR3C2 💬	[1] Aldosterone-regulated sodium reabsorption	[1] 210 💬
42	Sugar pill	-	-	-	-	[8]  5 ,  6 , 49, 67, 70, 86, 206, 210 💬
43	Tadalafil	Tadalafil	[1] D02008 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[7]  6 , 51, 75, 84, 86, 113, 210 💬
44	Tadalafil citrate	Tadalafil	[1] D02008 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[1] 210 💬
45	Tracleer	-	-	-	-	[8] 13, 51, 84, 85, 86, 88, 210, 211 💬
46	Treprostinil	Treprostinil	[1] D06213 💬	[1] PTGIR 💬	[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction	[6] 51, 84, 85, 86, 88, 210 💬
47	Udenafil	Udenafil	[1] D10027 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[2] 86, 210 💬
48	Vasopressin	Vasopressin	[1] D00101 💬	[3] AVPR1A, AVPR1B, AVPR2 💬	[5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption	[1] 210 💬
49	Vasopressin, arginine	Arginine	[2] D00101, D02982 💬	[3] AVPR1A, AVPR1B, AVPR2 💬	[5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption	[1] 210 💬
50	Vitamin c	Ascorbic acid	[1] D00018 💬	-	-	[6] 10, 192, 206, 210, 211, 212 💬
51	Xarelto	-	-	-	-	[2] 49, 210 💬

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