210. Single Ventricle
47 clinical trials,   54 drugs   (DrugBank: 23 drugs),   32 drug target genes,   66 drug target pathways

Searched query = "Single Ventricle", "SV", "Single ventricle heart defect", "Univentricular heart", "UVH", "Single ventricular circulation syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
4 trials found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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PhaseCountries
1NCT03430583
(ClinicalTrials.gov)
February 20, 201822/1/2018Evaluation of Fontan-Associated Liver DiseaseImaging and Biomarker Evaluation of Hepatic Stiffness in Children Enrolled in the Fontan Udenafil Exercise Longitudinal StudySingle Ventricle Heart DiseaseDrug: MZ101Mezzion Pharma Co. LtdNational Heart, Lung, and Blood Institute (NHLBI)Active, not recruiting12 YearsN/AAll100United States;Canada
2NCT03013751
(ClinicalTrials.gov)
January 20175/1/2017A Extension Study of Udenafil in AdolescentsA Phase III Extension Study of Udenafil in Adolescents With Single Ventricle Physiology After Fontan PalliationFunctional Single Ventricle Heart DiseaseDrug: UdenafilMezzion Pharma Co. LtdNational Heart, Lung, and Blood Institute (NHLBI)Active, not recruiting12 Years18 YearsAll300Phase 3United States;Canada;Korea, Republic of
3NCT02741115
(ClinicalTrials.gov)
July 22, 201610/4/2016Fontan Udenafil Exercise Longitudinal Assessment TrialFontan Udenafil Exercise Longitudinal Assessment Trial (FUEL)Single Ventricle Heart DiseaseDrug: Udenafil;Drug: PlaceboMezzion Pharma Co. LtdNational Heart, Lung, and Blood Institute (NHLBI)Completed12 Years18 YearsAll400Phase 3United States;Canada;Korea, Republic of
4NCT02201342
(ClinicalTrials.gov)
July 201424/7/2014Pharmacokinetic/Pharmacodynamic Study of Udenafil in AdolescentsA Phase I/II Dose Escalation Trial of Udenafil in Adolescents With Single Ventricle Physiology After Fontan PalliationSingle Ventricle Heart Disease After Fontan SurgeryDrug: UdenafilMezzion Pharma Co. LtdNational Heart, Lung, and Blood Institute (NHLBI);Pediatric Heart Network;National Heart, Lung, and Blood Institute (NHLBI);Pediatric Heart NetworkCompleted14 Years18 YearsBoth36Phase 1;Phase 2United States;Canada