Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	Amniotic epithelial cells	Amniotic Epithelial Cells	-	-	-	[1] 26 💬
2	Bortezomib	Bortezomib	[1] D03150 💬	[1] PSMB5 💬	[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia	[15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
3	Ciclosporin	Cyclosporine	[1] D00184 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	[32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	[13] 26, 46, 49, 50, 53, 55, 60, 61, 97, 222, 226, 228, 269 💬
4	Costicosteroids	-	-	-	-	[1] 26 💬
5	Cyclophosphamide	Cyclophosphamide	[2] D00287, D07760 💬	-	-	[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
6	Doxorubicin	Doxorubicin	[1] D03899 💬	[2] TOP2A, TOP2B 💬	[1] Platinum drug resistance	[4] 26, 28, 34, 331 💬
7	Doxorubicin hydrochloride	Doxorubicin	[1] D03899 💬	[2] TOP2A, TOP2B 💬	[1] Platinum drug resistance	[3] 26, 34, 331 💬
8	Etoposide	Etoposide	[2] D00125, D04107 💬	[2] TOP2A, TOP2B 💬	[1] Platinum drug resistance	[11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
9	Filgrastim	Filgrastim	[1] D03235 💬	[1] CSF3R 💬	[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer	[27]  2 ,  6 , 13, 25, 26, 28, 34, 35, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
10	Hu mik-beta-1	-	-	-	-	[1] 26 💬
11	Human interferon beta	Human interferon beta	-	-	-	[2] 13, 26 💬
12	Interferon alfa	Interferon alfa	[1] D03305 💬	[2] IFNAR1, IFNAR2 💬	[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway	[5] 25, 26, 28, 56, 96 💬
13	Interferon beta	Human interferon beta	-	-	-	[5] 13, 20, 26, 96, 97 💬
14	Interferon beta-1a	Human interferon beta	[1] D04554 💬	[2] IFNAR1, IFNAR2 💬	[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway	[4] 13, 26, 96, 97 💬
15	Kw-0761	-	-	-	-	[1] 26 💬
16	Kw-0761 0.3 mg/kg iv	-	-	-	-	[1] 26 💬
17	Lamivudine	Lamivudine	[1] D00353 💬	-	-	[6] 26, 42, 46, 135, 265, 325 💬
18	Lenalidomide	Lenalidomide	[1] D04687 💬	[1] TNF 💬	[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	[7] 16, 26, 28, 34, 49, 284, 300 💬
19	Methylprednisolone	Methylprednisolone	[6] D00407, D00751, D00979, D05000, D05001, D05002 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
20	Mogamulizumab	Mogamulizumab	[1] D09761 💬	[1] CCR4 💬	[5] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Kaposi sarcoma-associated herpesvirus infection, Viral carcinogenesis, Viral protein interaction with cytokine and cytokine receptor	[1] 26 💬
21	Nivolumab	Nivolumab	[1] D10316 💬	[1] PDCD1 💬	[3] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway	[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
22	Nk cells	Natural Killer Cell	-	-	-	[1] 26 💬
23	Other: laboratory biomarker analysis	-	-	-	-	[21] 11, 13, 14, 16, 26, 28, 34, 49, 51, 60, 62, 65, 89, 96, 97, 232, 283, 284, 285, 298, 331 💬
24	Other: pharmacogenomic study	-	-	-	-	[1] 26 💬
25	Pentosan polysulfate	Pentosan polysulfate	[1] D05428 💬	-	-	[3] 19, 26, 226 💬
26	Pentoxifylline	Pentoxifylline	[1] D00501 💬	-	-	[10] 26, 56, 84, 93, 96, 113, 220, 222, 296, 298 💬
27	Prednisolone	Prednisolone	[8] D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
28	Prednisone	Prednisone	[1] D00473 💬	[1] NR3C1 💬	[1] Neuroactive ligand-receptor interaction	[47]  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
29	Propantheline	Propantheline	[1] D00481 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway	[1] 26 💬
30	Propantheline bromide	Propantheline	[1] D00481 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway	[1] 26 💬
31	Raltegravir	Raltegravir	[1] D06676 💬	-	-	[4] 13, 26, 93, 265 💬
32	Raltegravir and zidovudine	Raltegravir	[2] D00413, D06676 💬	-	-	[1] 26 💬
33	Recombinant human interferon beta-1a	Human interferon beta	[1] D04554 💬	[2] IFNAR1, IFNAR2 💬	[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway	[1] 26 💬
34	Recombinant interferon alfa	Interferon alfa	[1] D03305 💬	[2] IFNAR1, IFNAR2 💬	[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway	[2] 26, 28 💬
35	Sulfate	Sulfate ion	-	-	-	[25]  2 ,  6 , 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 222, 226, 265, 296, 297, 299 💬
36	Tamibarotene	Tamibarotene	[1] D01418 💬	[1] RARA 💬	[5] Acute myeloid leukemia, Estrogen signaling pathway, Pathways in cancer, Th17 cell differentiation, Transcriptional misregulation in cancer	[2] 26, 96 💬
37	Valproic acid	Valproic acid	[1] D00399 💬	[7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	[10]  3 ,  5 , 26, 34, 65, 89, 90, 222, 256, 331 💬
38	Valproid acid plus corticosteroids	-	-	-	-	[1] 26 💬
39	Vincristine	Vincristine	[2] D02197, D08679 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection	[3] 26, 34, 331 💬
40	Vincristine sulfate	Sulfate ion	[2] D02197, D08679 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection	[2] 26, 34 💬
41	Zidovudine	Zidovudine	[1] D00413 💬	-	-	[6] 25, 26, 135, 265, 325, 331 💬
42	Zidovudine/lamivudine	Lamivudine	[2] D00353, D00413 💬	-	-	[1] 26 💬

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