1 |
Blinded cdca 250 mg tid |
Chenodeoxycholic acid |
[1] D00163 D00163 💬 |
NR1H4 [1] NR1H4 💬 |
Bile secretion [1] Bile secretion |
263 [1] 263 💬 |
2 |
Blood tests |
- |
- |
- |
- |
046 [2] 46, 263 💬 |
3 |
Cdca |
Chenodeoxycholic acid |
[1] D00163 D00163 💬 |
NR1H4 [1] NR1H4 💬 |
Bile secretion [1] Bile secretion |
263 [1] 263 💬 |
4 |
Cdca weight-based dose tid |
Chenodeoxycholic acid |
[1] D00163 D00163 💬 |
NR1H4 [1] NR1H4 💬 |
Bile secretion [1] Bile secretion |
263 [1] 263 💬 |
5 |
Chenodeoxycholic acid |
Chenodeoxycholic acid |
[1] D00163 D00163 💬 |
NR1H4 [1] NR1H4 💬 |
Bile secretion [1] Bile secretion |
020 [4] 20, 96, 234, 263 💬 |
6 |
Fpf1011 |
- |
- |
- |
- |
263 [1] 263 💬 |
7 |
Lovastatin |
Lovastatin |
[1] D00359 D00359 💬 |
HMGCR [1] HMGCR 💬 |
AMPK signaling pathway [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis |
006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
8 |
Open-label cdca 250 mg tid |
Chenodeoxycholic acid |
[1] D00163 D00163 💬 |
NR1H4 [1] NR1H4 💬 |
Bile secretion [1] Bile secretion |
263 [1] 263 💬 |
9 |
Rescue medication cdca 250 mg tid |
Chenodeoxycholic acid |
[1] D00163 D00163 💬 |
NR1H4 [1] NR1H4 💬 |
Bile secretion [1] Bile secretion |
263 [1] 263 💬 |