Drug    DrugBank | All Description Patterns💬 Info on mouse-over

No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	4-methylpyrazole	Fomepizole	[1] D00707 💬	[3] ADH1A, ADH1B, ADH1C 💬	[9] Chemical carcinogenesis, Drug metabolism - cytochrome P450, Fatty acid degradation, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pyruvate metabolism, Retinol metabolism, Tyrosine metabolism	[1] 301 💬
2	Acu-4429	-	-	-	-	[1] 301 💬
3	Alk-001	-	-	-	-	[1] 301 💬
4	Alk-001 (no generic name)	-	-	-	-	[1] 301 💬
5	Arc1905	-	-	-	-	[1] 301 💬
6	Arc1905 20 mg/ml	-	-	-	-	[1] 301 💬
7	Avacincaptad pegol	Avacincaptad pegol	-	-	-	[1] 301 💬
8	Dac	-	-	-	-	[3] 13, 90, 301 💬
9	Device: medmont darl adapted chromatic (dac)	-	-	-	-	[2] 90, 301 💬
10	Device: moncvone electrophysiology	-	-	-	-	[2] 90, 301 💬
11	Device: retmap, rm electrode	-	-	-	-	[2] 90, 301 💬
12	Dha	-	-	-	-	[8]  6 , 46, 48, 49, 94, 113, 299, 301 💬
13	Diagnostic test: ocular coherence tomography-angiography (oct-a)	-	-	-	-	[2] 90, 301 💬
14	Docosahexaenoic acid	Doconexent	-	-	-	[7]  6 , 49, 90, 94, 240, 299, 301 💬
15	Docosahexaenoic acid (dha) dietary supplement	Doconexent	-	-	-	[1] 301 💬
16	Emixustat	Emixustat	[1] D10348 💬	-	-	[1] 301 💬
17	Emixustat hydrochloride	Emixustat	[1] D10348 💬	-	-	[1] 301 💬
18	Emixustat hydrochloride (acu-4429)	Emixustat	[1] D10348 💬	-	-	[1] 301 💬
19	Epa	-	-	-	-	[6]  8 , 46, 48, 49, 113, 301 💬
20	Hesc-rpe	-	-	-	-	[1] 301 💬
21	Interferon gamma	Interferon Gamma	-	-	-	[8] 18, 65, 85, 107, 228, 299, 301, 326 💬
22	Interferon gamma-1b	Interferon Gamma	[1] D00747 💬	[2] IFNGR1, IFNGR2 💬	[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis	[7] 18, 65, 85, 228, 299, 301, 326 💬
23	Lentiviral vector containing abca4 gene	-	-	-	-	[1] 301 💬
24	Long term follow up in all patients who received sar422459 in previous study tdu13583	-	-	-	-	[1] 301 💬
25	Ma09-hrpe	-	-	-	-	[1] 301 💬
26	Madeos	-	-	-	-	[1] 301 💬
27	Metformin	Metformin	[2] D00944, D04966 💬	[2] PRKAA1, PRKAA2 💬	[19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway	[21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
28	Metformin hydrochloride	Metformin	[2] D00944, D04966 💬	[2] PRKAA1, PRKAA2 💬	[19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway	[5] 81, 158, 265, 299, 301 💬
29	Other: saline	-	-	-	-	[8]  2 ,  6 , 46, 97, 98, 256, 274, 301 💬
30	Other: sham	-	-	-	-	[2] 19, 301 💬
31	Other: standard of care sildenafil	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[2] 90, 301 💬
32	Other: visual acuity (va)	-	-	-	-	[2] 90, 301 💬
33	Over the counter dha/epa dietary supplementation	-	-	-	-	[1] 301 💬
34	Ranibizumab	Ranibizumab	[1] D05697 💬	[1] VEGFA 💬	[22] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway	[4] 34, 166, 227, 301 💬
35	Ranibizumab injection (0.5 mg)	Ranibizumab	[1] D05697 💬	[1] VEGFA 💬	[22] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway	[2] 166, 301 💬
36	Saffron supplementation	-	-	-	-	[1] 301 💬
37	Sar422459	-	-	-	-	[1] 301 💬
38	Sildenafil	Sildenafil	[2] D02229, D08514 💬	[1] PDE5A 💬	[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	[17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
39	Soraprazan	-	-	-	-	[1] 301 💬
40	Stargen	-	-	-	-	[1] 301 💬
41	Stem/progenitor cells transplantation	-	-	-	-	[2] 90, 301 💬
42	Stg-001	-	-	-	-	[1] 301 💬
43	Va	-	-	-	-	[3] 90, 301, 302 💬
44	Vett lentiviral con gene abca4	-	-	-	-	[1] 301 💬
45	Zimura	-	-	-	-	[1] 301 💬

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