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e.g. Sirolimus, Adalimumab

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164 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  (2)-epigallocatechin-3-gallate (egcg)  Epigallocatechin  -  -  -  [1]  8  💬 
 2  20 mg bid of pf-02545920  -  -  -  -  [1]  8  💬 
 3  20mg daily citalopram  Citalopram  [2] D00822, D07704 💬  [1] SLC6A4 💬  [2] Serotonergic synapse, Synaptic vesicle cycle  [1]  8  💬 
 4  5-chloro-1,2-dihydro-n-ethyl-4-hydroxy-1-methyl-2-oxo-n-phenyl-3-quinolinecarboxamide sodium  -  -  -  -  [1]  8  💬 
 5  [123i]mni-420  -  -  -  -  [2]  6 ,  8  💬 
 6  [18f]fpeb  -  -  -  -  [3]  6 ,  8 , 206 💬 
 7  Acr16  -  -  -  -  [1]  8  💬 
 8  Acr16 10 mg  -  -  -  -  [1]  8  💬 
 9  Acr16 22.5 mg  -  -  -  -  [1]  8  💬 
 10  Acr16 45 mg  -  -  -  -  [1]  8  💬 
 11  Acr16 hydrochloride, asp2314 hydrochloride, fr310826  -  -  -  -  [1]  8  💬 
 12  Afq056  -  -  -  -  [3]  6 ,  8 , 206 💬 
 13  Alprazolam  Alprazolam  [1] D00225 💬  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬  [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [1]  8  💬 
 14  Amantadine  Amantadine  [2] D00777, D07441 💬  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [4]  6 ,  8 , 13, 127 💬 
 15  Anti-parkinson medication  -  -  -  -  [5]  5 ,  6 ,  7 ,  8 , 17 💬 
 16  Anx005  -  -  -  -  [3]  2 ,  8 , 61 💬 
 17  Atomoxetine  Atomoxetine  [2] D02574, D07473 💬  [1] SLC6A2 💬  [1] Synaptic vesicle cycle  [3]  6 ,  8 , 13 💬 
 18  Autologous stem cell  -  -  -  -  [1]  8  💬 
 19  Bevantolol  Bevantolol  -  -  -  [1]  8  💬 
 20  Bevantolol hydrochloride  Bevantolol  -  -  -  [1]  8  💬 
 21  Biotin  Biotin  [1] D00029 💬  -  -  [5]  2 ,  8 , 10, 13, 20 💬 
 22  Blood sample  -  -  -  -  [13]  8 , 13, 46, 49, 51, 53, 61, 66, 84, 97, 274, 288, 299 💬 
 23  Bn82451b  -  -  -  -  [1]  8  💬 
 24  Bn8251b  -  -  -  -  [1]  8  💬 
 25  Bupropion  Bupropion  [3] D00817, D07591, D07938 💬  [2] SLC6A2, SLC6A3 💬  [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle  [5]  8 , 18, 21, 96, 171 💬 
 26  Calvan® 100 mg  -  -  -  -  [1]  8  💬 
 27  Cannabidiol  Cannabidiol  [1] D10915 💬  [2] CNR1, CNR2 💬  [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis  [17]  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 226, 271 💬 
 28  Cbd  -  -  -  -  [11]  2 ,  6 ,  8 , 13, 46, 140, 144, 145, 156, 158, 206 💬 
 29  Cellavita hd higher dose  -  -  -  -  [1]  8  💬 
 30  Cellavita hd lower dose  -  -  -  -  [1]  8  💬 
 31  Cellavita-hd  -  -  -  -  [1]  8  💬 
 32  Citalopram  Citalopram  [2] D00822, D07704 💬  [1] SLC6A4 💬  [2] Serotonergic synapse, Synaptic vesicle cycle  [6]  6 ,  8 , 13, 18, 46, 127 💬 
 33  Ckd-504  -  -  -  -  [1]  8  💬 
 34  Coenzyme q10  Ubidecarenone  [1] D01065 💬  -  -  [12]  2 ,  5 ,  6 ,  8 , 10, 18, 46, 57, 113, 193, 214, 215 💬 
 35  Coq10  -  -  -  -  [3]  5 ,  6 ,  8  💬 
 36  Creatine  Creatine  -  -  -  [12]  1 ,  2 ,  5 ,  6 ,  8 , 13, 46, 49, 50, 113, 156, 201 💬 
 37  Creatine monohydrate  Creatine  -  -  -  [4]  2 ,  8 , 113, 156 💬 
 38  Cystagon  -  -  -  -  [3]  8 , 19, 299 💬 
 39  Cysteamine  Cysteamine  [2] D03634, D03635 💬  -  -  [4]  8 , 19, 21, 299 💬 
 40  Cysteamine bitartrate  Cysteamine  [2] D03634, D03635 💬  -  -  [4]  8 , 19, 21, 299 💬 
 41  Delta-9-tetrahydrocannabinol  Dronabinol  [1] D00306 💬  [2] CNR1, CNR2 💬  [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis  [2]  8 , 13 💬 
 42  Delta-9-tetrahydrocannabinol (thc) and cannabidiol (cbd)  Cannabidiol  [2] D00306, D10915 💬  [2] CNR1, CNR2 💬  [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis  [1]  8  💬 
 43  Deutetrabenazine  Deutetrabenazine  [1] D10701 💬  [1] SLC18A2 💬  [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle  [1]  8  💬 
 44  Deutetrabenazine oral tablet [austedo]  Deutetrabenazine  [1] D10701 💬  [1] SLC18A2 💬  [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle  [1]  8  💬 
 45  Device: biostamp npoint device  -  -  -  -  [1]  8  💬 
 46  Device: deep brain stimulation  -  -  -  -  [5]  5 ,  6 ,  7 ,  8 , 17 💬 
 47  Dextromethorphan  Dextromethorphan  [3] D00848, D03742, D03744 💬  [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬  [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 
 48  Dextromethorphan/quinidine 20mg/10mg (dm/q 20mg/10mg)  Dextromethorphan  [7] D00642, D00643, D00848, D02272, D03742, D03744, D08458 💬  [11] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A, SIGMAR1 💬  [22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway  [1]  8  💬 
 49  Digoxin  Digoxin  [1] D00298 💬  [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬  [18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway  [3]  8 , 46, 210 💬 
 50  Dimebon  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 51  Dimebon (latrepirdine)  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 52  Dimebon + dextromethorphan  Dextromethorphan  [4] D00848, D03742, D03744, D09917 💬  [7] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 53  Dimebon + ketoconazole  Ketoconazole  [2] D00351, D09917 💬  [7] ACHE, CYP17A1, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [28] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Metabolic pathways, Neuroactive ligand-receptor interaction, Nicotine addiction, Ovarian steroidogenesis, Pathways of neurodegeneration - multiple diseases, Prion disease, Prolactin signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Steroid hormone biosynthesis, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 54  Dimebon + omeprazole  Latrepirdine  [5] D00455, D01207, D05259, D05261, D09917 💬  [8] ACHE, ATP4A, ATP4B, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [26] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Dopaminergic synapse, Gastric acid secretion, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Metabolic pathways, Neuroactive ligand-receptor interaction, Nicotine addiction, Oxidative phosphorylation, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 55  Dimebon alone  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 56  Dimebon dihydrochloride  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 57  Dimebon ir  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 58  Dimebon ir tablet  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 59  Dimebon mr1  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 60  Dimebon mr2  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 61  Dimebon mr3  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 62  Dimebon mr4  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 63  Dimebon transdermal  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 64  Divalproex  -  -  -  -  [1]  8  💬 
 65  Dm  -  -  -  -  [2]  6 ,  8  💬 
 66  Egcg  Epigallocatechin gallate  -  -  -  [9]  6 ,  8 , 13, 17, 28, 85, 113, 206, 299 💬 
 67  Epa  -  -  -  -  [6]  8 , 46, 48, 49, 113, 301 💬 
 68  Epigallocatechin  Epigallocatechin  -  -  -  [5]  8 , 13, 28, 85, 113 💬 
 69  Ethyl icosapent  Icosapent  [1] D08061 💬  -  -  [1]  8  💬 
 70  Ethyl-epa  Icosapent ethyl  [1] D01892 💬  -  -  [1]  8  💬 
 71  Ethyl-epa (miraxion™)  Icosapent ethyl  [1] D01892 💬  -  -  [1]  8  💬 
 72  Ethyl-icosapent  Icosapent  [1] D08061 💬  -  -  [1]  8  💬 
 73  Fenofibrate  Fenofibrate  [1] D00565 💬  [1] PPARA 💬  [8] Adipocytokine signaling pathway, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway  [5]  8 , 79, 93, 94, 265 💬 
 74  Graft intracerebral of foetal neurons  -  -  -  -  [1]  8  💬 
 75  Gsk356278  -  -  -  -  [1]  8  💬 
 76  Haloperidol  Haloperidol  [2] D00136, D01898 💬  [1] DRD2 💬  [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  8  💬 
 77  High doses of thiamine y biotin  Biotin  [2] D00029, D08580 💬  -  -  [1]  8  💬 
 78  Hyperium  Rilmenidine  [1] D08482 💬  [3] ADRA2A, ADRA2B, ADRA2C 💬  [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [1]  8  💬 
 79  Icosapent  Icosapent  [1] D08061 💬  -  -  [1]  8  💬 
 80  Isis 443139 10 mg  -  -  -  -  [1]  8  💬 
 81  Isis 443139 120 mg  -  -  -  -  [1]  8  💬 
 82  Isis 443139 30 mg  -  -  -  -  [1]  8  💬 
 83  Isis 443139 60 mg  -  -  -  -  [1]  8  💬 
 84  Isis 443139 90 mg  -  -  -  -  [1]  8  💬 
 85  Ketoconazole  Ketoconazole  [1] D00351 💬  [1] CYP17A1 💬  [6] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis  [3]  8 , 13, 75 💬 
 86  Laquinimod  Laquinimod  -  -  -  [4]  8 , 13, 49, 96 💬 
 87  Laquinimod capsules 0.5 mg  Laquinimod  -  -  -  [2]  8 , 96 💬 
 88  Latrepirdine  Latrepirdine  [1] D09917 💬  [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [1]  8  💬 
 89  Lax-101  LAX-101  -  -  -  [1]  8  💬 
 90  Lithium  -  -  -  -  [5]  2 ,  5 ,  6 ,  7 ,  8  💬 
 91  Melatonin  Melatonin  [1] D08170 💬  [2] MTNR1A, MTNR1B 💬  [2] Circadian entrainment, Neuroactive ligand-receptor interaction  [11]  6 ,  8 , 13, 46, 49, 90, 97, 144, 145, 149, 202 💬 
 92  Memantine  Memantine  [2] D04905, D08174 💬  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [7]  2 ,  6 ,  8 , 13, 49, 127, 205 💬 
 93  Minocycline  Minocycline  [2] D00850, D05045 💬  -  -  [13]  2 ,  6 ,  8 , 13, 46, 85, 90, 94, 162, 201, 206, 280, 299 💬 
 94  Moderate doses of thiamine y biotin  Biotin  [2] D00029, D08580 💬  -  -  [1]  8  💬 
 95  N.a.  -  -  -  -  [10]  3 ,  6 ,  8 , 13, 46, 96, 97, 240, 256, 271 💬 
 96  Neflamapimod  Neflamapimod  [1] D10959 💬  [4] MAPK11, MAPK12, MAPK13, MAPK14 💬  [58] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection  [1]  8  💬 
 97  Nilotinib  Nilotinib  [1] D08953 💬  [4] ABL1, KIT, PDGFRA, PDGFRB 💬  [32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis  [5]  6 ,  8 , 34, 51, 86 💬 
 98  Nilotinib 150 mg  Nilotinib  [1] D08953 💬  [4] ABL1, KIT, PDGFRA, PDGFRB 💬  [32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis  [1]  8  💬 
 99  Olanzapine  Olanzapine  [2] D00454, D06623 💬  [11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬  [16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [2]  2 ,  8  💬 
 100  Omeprazole  Omeprazole  [4] D00455, D01207, D05259, D05261 💬  [2] ATP4A, ATP4B 💬  [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation  [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 
 101  Oms643762  -  -  -  -  [1]  8  💬 
 102  Osu6162 similar to (-)-osu 6162  -  -  -  -  [2]  6 ,  8  💬 
 103  Other: 31-phosphorus rmn spectroscopy  Phosphorus  -  -  -  [1]  8  💬 
 104  Pbf-999  -  -  -  -  [1]  8  💬 
 105  Pbf-999 / 160 mg  -  -  -  -  [1]  8  💬 
 106  Pbf-999 / 320 mg  -  -  -  -  [1]  8  💬 
 107  Pbt2  -  -  -  -  [1]  8  💬 
 108  Pf-02545920  -  -  -  -  [1]  8  💬 
 109  Phenylbutyrate  Phenylbutyric acid  [1] D05868 💬  -  -  [11]  2 ,  3 ,  6 ,  8 , 15, 93, 94, 244, 251, 297, 299 💬 
 110  Phosphorus  Phosphorus  -  -  -  [1]  8  💬 
 111  Pl101  -  -  -  -  [1]  8  💬 
 112  Pridiopidine  -  -  -  -  [1]  8  💬 
 113  Pridopidina  -  -  -  -  [1]  8  💬 
 114  Pridopidine  Pridopidine  [1] D09953 💬  [1] DRD2 💬  [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [3]  2 ,  6 ,  8  💬 
 115  Pridopidine (90 mg)  Pridopidine  [1] D09953 💬  [1] DRD2 💬  [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  8  💬 
 116  Pridopidine hydrochloride  Pridopidine  [1] D09953 💬  [1] DRD2 💬  [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  8  💬 
 117  Quinidine  Quinidine  [4] D00642, D00643, D02272, D08458 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [3]  2 ,  8 , 13 💬 
 118  Ramelteon  Ramelteon  [1] D02689 💬  [2] MTNR1A, MTNR1B 💬  [2] Circadian entrainment, Neuroactive ligand-receptor interaction  [3]  6 ,  8 , 46 💬 
 119  Resveratrol  Resveratrol  -  -  -  [6]  2 ,  8 , 18, 89, 113, 299 💬 
 120  Rg6042, formerly isis 443139, ionis-httrx  -  -  -  -  [1]  8  💬 
 121  Rilmenidine  Rilmenidine  [1] D08482 💬  [3] ADRA2A, ADRA2B, ADRA2C 💬  [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [1]  8  💬 
 122  Riluzole  Riluzole  [1] D00775 💬  [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬  [23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway  [8]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 206 💬 
 123  Risperidone  Risperidone  [1] D00426 💬  [2] DRD2, HTR2A 💬  [11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway  [5]  8 , 156, 179, 187, 206 💬 
 124  Ro 723-4292/f02  -  -  -  -  [1]  8  💬 
 125  Ro7234292  -  -  -  -  [1]  8  💬 
 126  Ro7234292 (rg6042)  -  -  -  -  [1]  8  💬 
 127  Rolipram  Rolipram  [1] D01783 💬  [4] PDE4A, PDE4B, PDE4C, PDE4D 💬  [5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway  [2]  8 , 13 💬 
 128  Rp 103  -  -  -  -  [2]  8 , 19 💬 
 129  Rp103  -  -  -  -  [2]  8 , 19 💬 
 130  Sage-718  -  -  -  -  [2]  6 ,  8  💬 
 131  Sbt-020  -  -  -  -  [1]  8  💬 
 132  Sd-809  -  -  -  -  [1]  8  💬 
 133  Selisistat  Selisistat  -  -  -  [1]  8  💬 
 134  Sen0014196  -  -  -  -  [1]  8  💬 
 135  Sen0014196 (high dose)  -  -  -  -  [1]  8  💬 
 136  Sen0014196 (low dose)  -  -  -  -  [1]  8  💬 
 137  Sodium phenylbutyrate  Phenylbutyric acid  [1] D05868 💬  -  -  [4]  2 ,  3 ,  8 , 251 💬 
 138  Som3355 100mg bid  -  -  -  -  [1]  8  💬 
 139  Som3355 200mg bid  -  -  -  -  [1]  8  💬 
 140  Srx246  -  -  -  -  [1]  8  💬 
 141  Ss-20  -  -  -  -  [1]  8  💬 
 142  Tetrabenazine  Tetrabenazine  [1] D08575 💬  [1] SLC18A2 💬  [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle  [1]  8  💬 
 143  Tetrabenazine withdrawal  Tetrabenazine  [1] D08575 💬  [1] SLC18A2 💬  [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle  [1]  8  💬 
 144  Tetrahydrocannabinol  Dronabinol  [1] D00306 💬  [2] CNR1, CNR2 💬  [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis  [3]  8 , 13, 298 💬 
 145  Thc  -  -  -  -  [4]  8 , 13, 46, 96 💬 
 146  Thiamine  Thiamine  [1] D08580 💬  -  -  [3]  8 , 13, 265 💬 
 147  Tiapridal  -  -  -  -  [1]  8  💬 
 148  Tominersen  -  -  -  -  [1]  8  💬 
 149  Triheptanoin  Triheptanoin  [1] D11465 💬  -  -  [9]  2 ,  8 , 149, 156, 248, 256, 257, 317, 324 💬 
 150  Triheptanoin 1g/kg/day  Triheptanoin  [1] D11465 💬  -  -  [1]  8  💬 
 151  Triheptanoin oil  Triheptanoin  [1] D11465 💬  -  -  [1]  8  💬 
 152  Tv-5600  -  -  -  -  [3]  8 , 13, 96 💬 
 153  Tv-7820  -  -  -  -  [1]  8  💬 
 154  Ubiquinol  Ubiquinol  -  -  -  [3]  6 ,  8 , 17 💬 
 155  Ursodiol  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [6]  8 , 20, 93, 97, 234, 299 💬 
 156  Ux007  -  -  -  -  [4]  8 , 248, 256, 257 💬 
 157  Valbenazine  Valbenazine  [1] D10675 💬  [1] SLC18A2 💬  [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle  [1]  8  💬 
 158  Vx-745  -  -  -  -  [1]  8  💬 
 159  Vx15/2503  -  -  -  -  [2]  8 , 13 💬 
 160  Warfarin  Warfarin  [3] D00564, D01280, D08682 💬  [2] NQO1, VKORC1 💬  [6] Biosynthesis of cofactors, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis  [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 
 161  Wve-120101  -  -  -  -  [1]  8  💬 
 162  Wve-120102  -  -  -  -  [1]  8  💬 
 163  Xenazine  -  -  -  -  [1]  8  💬 
 164  Zoloft  -  -  -  -  [1]  8  💬 

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