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257 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  2-(4-[5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy)-n-(methylsulfonyl)actamide  [1] 86 💬 
 2  90 mg hydrocortisone acetate suppository with sephure suppository applicator  Acetate  [2] D00088, D00165 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 97 💬 
 3  A novel synthetic, orally-administered, non-peptide small molecule, which acts as  [1] 254 💬 
 4  A-dopamine  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 5  Abatacept active treatment  Abatacept  [1] D03203 💬  [2] CD80, CD86 💬  [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis  [1] 50 💬 
 6  Abatacept, rituximab or tocilizumab  Abatacept  [3] D02596, D02994, D03203 💬  [4] CD80, CD86, IL6R, MS4A1 💬  [24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 7  Act  [1] 13 💬 
 8  Act - 064992  [1] 86 💬 
 9  Act-050089  [1] 86 💬 
 10  Act-050089 (ro 61-0612)  [1] 86 💬 
 11  Act-064992  [5] 51, 85, 86, 88, 210 💬 
 12  Act-064992 (macitentan)  Macitentan  [1] D10135 💬  [2] EDNRA, EDNRB 💬  [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 85 💬 
 13  Act-064992d  [1] 86 💬 
 14  Act-1  [1] 13 💬 
 15  Act-128800  Ponesimod  [1] D11215 💬  [1] S1PR1 💬  [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway  [1] 13 💬 
 16  Act-128800 dose 1  Ponesimod  [1] D11215 💬  [1] S1PR1 💬  [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway  [1] 13 💬 
 17  Act-128800 dose 2  Ponesimod  [1] D11215 💬  [1] S1PR1 💬  [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway  [1] 13 💬 
 18  Act-128800 dose 3  Ponesimod  [1] D11215 💬  [1] S1PR1 💬  [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway  [1] 13 💬 
 19  Act-178418  [1] 86 💬 
 20  Act-293987  [3] 51, 86, 88 💬 
 21  Act-293987 (ns-304)  [1] 86 💬 
 22  Act-293987 / jnj-67896049  [1] 84 💬 
 23  Act-334441  [1] 49 💬 
 24  Act-385781a  [1] 86 💬 
 25  Act-385781a (actelion epoprostenol)  Epoprostenol  [2] D00106, D01337 💬  [1] PTGIR 💬  [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction  [1] 86 💬 
 26  Act-434964  [1] 19 💬 
 27  Actemra  [2] 46, 107 💬 
 28  Actemra(eu-licensed)  [1] 46 💬 
 29  Actemra, mra  [1] 107 💬 
 30  Acteoside  Acteoside  [1] 66 💬 
 31  Acth  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [5] 13, 66, 145, 193, 222 💬 
 32  Acth (acthar) gel  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 66 💬 
 33  Acthar  [9]  2 , 13, 14, 46, 49, 50, 66, 84, 222 💬 
 34  Acthar 80 unit injection  [1] 66 💬 
 35  Acthar gel  [6] 13, 46, 49, 50, 84, 222 💬 
 36  Acthar gel (acth)  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 13 💬 
 37  Acthar gel (adrenocorticotropic hormone)  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 84 💬 
 38  Acthar gel 40 units twice weekly  [1] 84 💬 
 39  Acthar gel 80 units twice weekly.  [1] 84 💬 
 40  Acthar high dose (80 u)  [1] 49 💬 
 41  Acthar injectable product  [1] 46 💬 
 42  Acthar low dose (40 u)  [1] 49 💬 
 43  Acthrel  [1] 75 💬 
 44  Actimmune  [1] 326 💬 
 45  Actimmune registry  [1] 326 💬 
 46  Active bmn 111: daily subcutaneous injection of 15 ug/kg of bmn 111  [1] 276 💬 
 47  Active comparator  [2]  6 , 46 💬 
 48  Active comparator receiving extavia®  [1] 13 💬 
 49  Active control  [1] 13 💬 
 50  Active drug (biib014) at 10, 30, 100, or 300 mg once daily.  [1]  6  💬 
 51  Active drug: pimavanserin 17mg (2 strength tablets)  Pimavanserin  [1]  6  💬 
 52  Active group  [1] 97 💬 
 53  Active investigational treatment ent-01  [1]  6  💬 
 54  Active topical ns2 1% dermatologic cream  [1] 160 💬 
 55  Active treatment group 7% hypertonic saline  [1] 299 💬 
 56  Actonel 5mg film coated tablets  [1] 274 💬 
 57  Actonel once a week 35 mg film-coated tablets  [1] 274 💬 
 58  Actonel once a week 5mg film coated tablets  [1] 113 💬 
 59  Actonel/optinate 5mg film-coated tablets  [1] 274 💬 
 60  Actos (pioglitazone)  Pioglitazone  [2] D00945, D08378 💬  [1] PPARG 💬  [9] AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer  [1] 13 💬 
 61  Actos 15 mg  [1]  2  💬 
 62  Actos 30 mg  [1]  2  💬 
 63  Actos 45 mg  [1]  2  💬 
 64  Actrapid 100 iu/ml, solution for injection in a vial  [1] 299 💬 
 65  Actrapid penfill 100ui/ml  [1] 299 💬 
 66  Actriia-igg1fc  [1] 86 💬 
 67  Adalimuab, etanercept, tocilizumab, or abatacept  Abatacept  [3] D00742, D02596, D03203 💬  [5] CD80, CD86, IL6R, LTA, TNF 💬  [77] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cell adhesion molecules, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [1] 46 💬 
 68  Adjuvant without active component  [2]  6 , 17 💬 
 69  Adrenocorticotrophic hormone acth  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 222 💬 
 70  Adrenocorticotropic hormone (acth) gel (h.p. acthar®)  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 13 💬 
 71  Anti baff (b cell activating factor)  [1] 49 💬 
 72  Antimicrobial therapy: co-trimoxazole or doxycycline  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [1] 85 💬 
 73  Anxiety/depression and work and activities  [1] 13 💬 
 74  Behavioral: bci-fit active querying  [3]  2 ,  6 , 17 💬 
 75  Behavioral: physical activity together for pwms and their cgs (pat-ms)  [1] 13 💬 
 76  Behavioral: role of dopamine  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 77  Biologically active human fecal microbiota  [1] 97 💬 
 78  Bromocriptine and other dopamine agonists  Bromocriptine  [4] D00633, D00780, D03165, D07870 💬  [6] DRD1, DRD2, DRD3, DRD4, DRD5, PRL 💬  [15] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 79  Bt-11 active  [2] 96, 97 💬 
 80  Cerebral dopamine neurotrophic factor  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 81  Cfz533 active - cohort 1  [1] 53 💬 
 82  Cfz533 active - cohort 2  [1] 53 💬 
 83  Cfz533 active - cohort 3  [1] 53 💬 
 84  Cfz533 active -cohort 3  [1] 53 💬 
 85  Cjnj-68150420-zzz-g001 (act- 064992d)  [1] 86 💬 
 86  Cjnj-68150420-zzz-g001 (act-064992d)  [1] 86 💬 
 87  Cjnj-68150420-zzz-g001(act-064992d)  [1] 86 💬 
 88  Combination oral budesonide and rectal hydrocortisone  Budesonide  [2] D00088, D00246 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 97 💬 
 89  Combination product: active treatment with dual therapy  [1]  2  💬 
 90  Combination product: twice daily 90 mg hydrocortisone acetate suppository administered with sephure applicator  Acetate  [2] D00088, D00165 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 97 💬 
 91  Continuous release dopamine agonists  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 92  Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone)  Acetate  [21] D00088, D00292, D00472, D00473, D00973, D00975, D00980, D00981, D00982, D01239, D01510, D01615, D01632, D01948, D01998, D02156, D02174, D02591, D02592, D03301, D07749 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 93  Cortef (hydrocortisone)  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 83 💬 
 94  Corticoids+ tocilizumab 8mg/kg/4 weeks  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 41 💬 
 95  Corticotropin  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [7]  2 , 13, 46, 75, 78, 84, 222 💬 
 96  Corticotropin-releasing hormone  Corticorelin  [2] D00146, D03905 💬  [3] CRHR1, CRHR2, MC2R 💬  [6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 75 💬 
 97  Decrease tocilizumab, abatacept  Abatacept  [2] D02596, D03203 💬  [3] CD80, CD86, IL6R 💬  [24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 98  Device: actimyo recording  [1]  6  💬 
 99  Device: activated smart device  [1] 299 💬 
 100  Device: active stimulation  [1] 46 💬 
 101  Device: active tdcs  [1]  6  💬 
 102  Device: active tpcs  [1]  6  💬 
 103  Device: activity monitor  Methamidophos  [1] 113 💬 
 104  Device: de-activated smart device  [1] 299 💬 
 105  Device: nanocrystalline silver (acticoat)  Silver  [2] 35, 162 💬 
 106  Device: omnidirectional accelerometer monitor (3x3 cm and 16 g, actical®, philips respironics)  Methamidophos  [1] 118 💬 
 107  Device: wristband physical activity monitor  Methamidophos  [1] 13 💬 
 108  Diagnostic test: disease activity  [1] 46 💬 
 109  Diagnostic test: dm1-activc  [1] 113 💬 
 110  Diagnostic test: fibrinogen plasma concentration, coagulation factor xiii activity  Factor XIII (human)  [1] 288 💬 
 111  Dopamine  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [3]  6 ,  7 , 74 💬 
 112  Dopamine agent  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 113  Dopamine agonist treatment  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1] 74 💬 
 114  Dopamine agonists  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1] 74 💬 
 115  Dopamine agonists (pramipexole, ropirinole)  Dopamine  [4] D00559, D00633, D05575, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 116  Doxycycline  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [15] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 162, 167, 227, 280, 299 💬 
 117  Doxycycline 100 mg capsules  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [1] 89 💬 
 118  Doxycycline 100-200mg capsules daily for 6 months  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [1] 167 💬 
 119  Doxycycline hyclate  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [3] 23, 96, 227 💬 
 120  Doxycycline hyclate ph.eur  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [1] 167 💬 
 121  Doxycycline tablets  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [1] 46 💬 
 122  Dual release hydrocortisone (plenadren)  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 123  Efi/act-385781a  [1] 86 💬 
 124  Epoprostenol-actelion  Epoprostenol  [2] D00106, D01337 💬  [1] PTGIR 💬  [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction  [1] 86 💬 
 125  Etanercepet, rituximab, abatacept, tocilizumab, sarilumab  Abatacept  [4] D02596, D02994, D03203, D10161 💬  [4] CD80, CD86, IL6R, MS4A1 💬  [24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 126  Fentanyl  Fentanyl  [2] D00320, D01399 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [4] 46, 70, 215, 231 💬 
 127  Fentanyl (high dose)  Fentanyl  [2] D00320, D01399 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 215 💬 
 128  Fentanyl (low dose)  Fentanyl  [2] D00320, D01399 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 215 💬 
 129  Fentanyl (low dose) + dexmedetomidine  Dexmedetomidine  [4] D00320, D00514, D01205, D01399 💬  [4] ADRA2A, ADRA2B, ADRA2C, OPRM1 💬  [4] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [1] 215 💬 
 130  Fentanyl transdermal patch  Fentanyl  [2] D00320, D01399 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 46 💬 
 131  Gene activated human glucocerebrosidase  [1] 19 💬 
 132  Gene activated human glucocerebrosidase, velaglucerase alfa  Velaglucerase alfa  [1] D09029 💬  [1] GBA 💬  [4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism  [1] 19 💬 
 133  Gene-activated human glucocerebrosidase  [1] 19 💬 
 134  Gene-activated human glucocerebrosidase 200u/vial  [1] 19 💬 
 135  Gene-activated human glucocerebrosidase 400u/vial  [1] 19 💬 
 136  H.p. acthar gel  [5] 46, 49, 50, 84, 222 💬 
 137  H.p. acthar gel (repository corticotropin injection)  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 13 💬 
 138  H.p. acthar® gel  [1] 14 💬 
 139  Hril-2 active  [3] 46, 49, 53 💬 
 140  Hydrocortisone  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [9]  6 , 46, 53, 75, 78, 81, 83, 97, 299 💬 
 141  Hydrocortisone (solucortef)  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 142  Hydrocortisone 100mg/ml  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 83 💬 
 143  Hydrocortisone 10mg  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 46 💬 
 144  Hydrocortisone 10mg tablet  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 145  Hydrocortisone 10mg tablets  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 146  Hydrocortisone 20mg tablets  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 147  Hydrocortisone acetate  Acetate  [2] D00088, D00165 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 97 💬 
 148  Hydrocortisone cream  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1]  6  💬 
 149  Hydrocortisone cream 1%  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1]  6  💬 
 150  Hydrocortisone cream 10mg/g fna fagron  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1]  6  💬 
 151  Hydrocortisone hydrogen succinate  Hydrocortisone  [2] D00088, D01442 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 83 💬 
 152  Hydrocortisone modified release capsules  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 153  Hydrocortisone roussel  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 83 💬 
 154  Hydrocortisone sodium acetate  Acetate  [2] D00088, D01779 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 155  Hydrocortisone sodium phosphate  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [3] 53, 81, 83 💬 
 156  Hydrocortisone sodium succinate  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [3] 81, 83, 97 💬 
 157  Hydrocortisone tablet 2.5 mg  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 158  Hydrocortisone takeda, tabletter  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 78 💬 
 159  Inn-tocilizumab  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 266 💬 
 160  Interferon beta 1a, oral doxycycline  Doxycycline  [6] D00307, D02129, D03903, D03904, D04554, D07876 💬  [2] IFNAR1, IFNAR2 💬  [18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway  [1] 13 💬 
 161  Interferon gamma-1b  Interferon Gamma  [1] D00747 💬  [2] IFNGR1, IFNGR2 💬  [18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis  [7] 18, 65, 85, 228, 299, 301, 326 💬 
 162  Interferon gamma-1b (actimmune)  Interferon Gamma  [1] D00747 💬  [2] IFNGR1, IFNGR2 💬  [18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis  [1] 85 💬 
 163  Intra-articular tocilizumab  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 164  Jnj-67896049 (act-293987)  [1] 86 💬 
 165  Jnj-67896062 / act-064992  [2] 86, 88 💬 
 166  Lamotrigin actavis  [1] 114 💬 
 167  Long-acting somatostatin  Somatostatin  [1] D07431 💬  [5] SSTR1, SSTR2, SSTR3, SSTR4, SSTR5 💬  [4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 67 💬 
 168  Macitentan (act-064992)  Macitentan  [1] D10135 💬  [2] EDNRA, EDNRB 💬  [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 86 💬 
 169  Mesalazine with hydrocortisone sodium succinate  Hydrocortisone  [2] D00088, D00377 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 97 💬 
 170  Mra (actemra)  [1] 107 💬 
 171  Mra (tocilizumab)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [2] 46, 107 💬 
 172  Mra(tocilizumab)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [2] 46, 107 💬 
 173  Mra, actemra  [2] 46, 107 💬 
 174  Multi-modal pain management [fentanyl]  Fentanyl  [2] D00320, D01399 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 70 💬 
 175  Novorapid / humalog short acting insulin  [1] 299 💬 
 176  Octreotide lar / sandostatin lar (lar=long acting release)  Octreotide  [2] D00442, D06495 💬  [1] SSTR2 💬  [4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 84 💬 
 177  Other: corticotropin releasing hormone (crh)  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 78 💬 
 178  Other: fitbit activity monitor  Methamidophos  [1] 49 💬 
 179  Other: hydrocortisone  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 75 💬 
 180  Other: low dose (1 mcg) acth stimulation test  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 193 💬 
 181  Other: no active treatment  [1] 274 💬 
 182  Other: no doxycycline  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [1] 299 💬 
 183  Other: noninvasive actigraphy monitor  Methamidophos  [1] 86 💬 
 184  Other: tampa kinesiophobia scale, berg-balance test, international physical activity questionnaire-short form, falls efficacy scale  Isoxaflutole  [1]  6  💬 
 185  Ovine corticotropin-releasing hormone (ocrh)  Corticorelin  [2] D00146, D03905 💬  [3] CRHR1, CRHR2, MC2R 💬  [6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 75 💬 
 186  Pioglitazone  Pioglitazone  [2] D00945, D08378 💬  [1] PPARG 💬  [9] AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer  [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 
 187  Pioglitazone 15 mg  Pioglitazone  [2] D00945, D08378 💬  [1] PPARG 💬  [9] AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer  [1] 96 💬 
 188  Pioglitazone and tretinoin  Pioglitazone  [3] D00094, D00945, D08378 💬  [4] PML, PPARG, RARA, RARB 💬  [19] AMPK signaling pathway, Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Huntington disease, Influenza A, Longevity regulating pathway, Non-small cell lung cancer, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis  [1]  2  💬 
 189  Pioglitazone or metformin  Metformin  [4] D00944, D00945, D04966, D08378 💬  [3] PPARG, PRKAA1, PRKAA2 💬  [25] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Huntington disease, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Osteoclast differentiation, Oxytocin signaling pathway, PI3K-Akt signaling pathway, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Tight junction, Transcriptional misregulation in cancer, mTOR signaling pathway  [1] 265 💬 
 190  Procedure: embryonic dopamine cell implant surgery  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 191  Procedure: hydrocortisone withdrawal  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 192  Recombinant human cerebral dopamine neurotrophic factor  Dopamine  [2] D00633, D07870 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 193  Reh-acteoside  Acteoside  [1] 66 💬 
 194  Repository corticotropin injection  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [5]  2 , 13, 46, 84, 222 💬 
 195  Repository corticotropin injection -treatment extension  Corticotropin  [1] D00146 💬  [1] MC2R 💬  [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 84 💬 
 196  Risedronate sodium (actonel)  Risedronic acid  [3] D00942, D03234, D08484 💬  [1] FDPS 💬  [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis  [1] 274 💬 
 197  Risedronic acid  Risedronic acid  [3] D00942, D03234, D08484 💬  [1] FDPS 💬  [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis  [3] 93, 95, 274 💬 
 198  Rituximab, observational study amon patients with active ra  Rituximab  [1] D02994 💬  [1] MS4A1 💬  [1] Hematopoietic cell lineage  [1] 46 💬 
 199  Ro 47-0203 / act-050088  [1] 86 💬 
 200  Ro actemra  [1] 46 💬 
 201  Ro-actemra  [1] 46 💬 
 202  Ro47-0203 / act-050088  [2] 51, 86 💬 
 203  Sar156597 (act14604)  [1] 51 💬 
 204  Selexipag, act-293987 (ns-304)  Selexipag  [1] D09994 💬  [1] PTGIR 💬  [3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction  [1] 86 💬 
 205  Short-acting insulin (actrapid)  [1] 299 💬 
 206  Solu-cortef (hydrocortisone)  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 83 💬 
 207  Solu-cortef, powder for solution for injection, 100mg, and 'act-o-vial'  [1]  6  💬 
 208  Standard analgesia use [fentanyl]  Fentanyl  [2] D00320, D01399 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [1] 70 💬 
 209  Subcutaneous hydrocortisone  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 81 💬 
 210  Subcutaneous hydrocortisone 10mg  Hydrocortisone  [1] D00088 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1]  6  💬 
 211  Subcutaneous tocilizumab  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 212  Time and attention + active fructooligosaccharide supplementation  [1] 96 💬 
 213  Tocilizumab  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [18]  2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 
 214  Tocilizumab (actemra or roactemra)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 215  Tocilizumab (actemra)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 216  Tocilizumab (actemra®)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 217  Tocilizumab (mra-sc)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 40 💬 
 218  Tocilizumab (tcz)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [2] 46, 56 💬 
 219  Tocilizumab + glucocorticoids (gcs)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 41 💬 
 220  Tocilizumab + methotrexate(mtx)  Methotrexate  [3] D00142, D02115, D02596 💬  [3] DHFR, DHFR2, IL6R 💬  [17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 221  Tocilizumab 162 mg  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 222  Tocilizumab 162mg/0.9ml jeringa sc  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 223  Tocilizumab 162mg/0.9ml sc pfs sc  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 224  Tocilizumab 162mg/0.9ml syringe sc  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 225  Tocilizumab [roactemra/actemra]  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [4] 46, 51, 107, 331 💬 
 226  Tocilizumab [roactemra]  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 227  Tocilizumab and iv steroids combination  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 41 💬 
 228  Tocilizumab infusion roacemtra (eu)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 266 💬 
 229  Tocilizumab injection  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 13 💬 
 230  Tocilizumab iv  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 231  Tocilizumab plus methotrexate  Methotrexate  [3] D00142, D02115, D02596 💬  [3] DHFR, DHFR2, IL6R 💬  [17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 232  Tocilizumab prefilled syringe  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 233  Tocilizumab roche  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [2] 46, 107 💬 
 234  Tocilizumab sc  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [3] 41, 46, 107 💬 
 235  Tocilizumab sc 162 mg/0.9 ml disposable auto-injector (ai)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 236  Tocilizumab sc 162 mg/0.9 ml pre-filled syringe with safety device (pfs)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 237  Tocilizumab sc 162 mg/0.9 ml prefilled syringe with safety device (pfs)  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 51 💬 
 238  Tocilizumab treatment  Tocilizumab  [1] D02596 💬  [1] IL6R 💬  [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 41 💬 
 239  Tocilizumab+methotrexate(mtx)  Methotrexate  [3] D00142, D02115, D02596 💬  [3] DHFR, DHFR2, IL6R 💬  [17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 240  Tocilizumab, abatacept  Abatacept  [2] D02596, D03203 💬  [3] CD80, CD86, IL6R 💬  [24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor  [1] 46 💬 
 241  Transdermal fentanyl matrix, gabapentin  Fentanyl  [3] D00320, D00332, D01399 💬  [6] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, OPRM1, SLC6A1 💬  [12] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Estrogen signaling pathway, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Synaptic vesicle cycle  [1] 70 💬 
 242  Treatment defined only by active substance  [1] 50 💬 
 243  Treatment with systemic therapy (doxycycline)  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [1] 162 💬 
 244  Tretinoin and pioglitazone hcl  Pioglitazone  [3] D00094, D00945, D08378 💬  [4] PML, PPARG, RARA, RARB 💬  [19] AMPK signaling pathway, Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Huntington disease, Influenza A, Longevity regulating pathway, Non-small cell lung cancer, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis  [1]  2  💬 
 245  Udca (ursodeoxycholic acid)  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [1] 93 💬 
 246  Ursodeoxycholic acid  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [8]  6 , 67, 84, 93, 94, 95, 96, 97 💬 
 247  Ursodeoxycholic acid (udca)  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [1] 94 💬 
 248  Ursodeoxycholic acid (urso)  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [1] 93 💬 
 249  Ursodeoxycholic acid 300mg capsule  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [1] 93 💬 
 250  Ursodeoxycholic acid 300mg tablet  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [1] 93 💬 
 251  Ursodeoxycholic acid capsules  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [1] 93 💬 
 252  Ursodeoxycholic acid combination of immunosuppressive agents  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [2] 93, 95 💬 
 253  Ursodeoxycholic acid combined with total glucosides of paeony  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [1] 93 💬 
 254  Ursodeoxycholic acid only  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [1] 93 💬 
 255  Ursodeoxycholic acid+low dose glucocorticoid(prednisone)  Prednisone  [2] D00473, D00734 💬  [2] NR1H4, NR3C1 💬  [2] Bile secretion, Neuroactive ligand-receptor interaction  [1] 93 💬 
 256  Ursodiol (ursodeoxycholic acid, udca)  Ursodeoxycholic acid  [1] D00734 💬  [1] NR1H4 💬  [1] Bile secretion  [1] 97 💬 
 257  Uttr1147a/ro7021610 (active)  [2] 96, 97 💬 

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