DDrare: Database of Drug Development for Rare Diseases

Searched query = "Prion disease", "Creutzfeldt-Jakob disease", "CJD", "Gerstmann-Straussler-Scheinker syndrome", "Fatal familial insomnia", "Kuru disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = BASSADO; BASSADO 10CPS 100MG; DOXYCYCLINE HYCLATE; Doxycycline; Quinacrine

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2010-022233-28-IT (EUCTR)	20/06/2011	05/03/2012		Fatal familial insomnia: preventive treatment with doxycycline of at risk individuals - Doxycycline in FFI individuals	Subjects born between 1958 and 1969 belonging to the Treviso FFI family, tested previously for Prion D178N/129M mutation MedDRA version: 14.1;Level: SOC;Classification code 10029205;Term: Nervous system disorders;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Trade Name: BASSADO INN or Proposed INN: DOXYCYCLINE HYCLATE	IST. DI RICERCHE FARMACOLOG. M. NEGRI	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Italy
2	EUCTR2006-001858-27-IT (EUCTR)	21/06/2006	12/04/2007	A randomized, double-blind pilot study vs placebo for the evaluation of efficacy and tolerability of doxycline administered by oral route in patients affected by Creutzfeldt-Jakob disease. - ND	A randomized, double-blind pilot study vs placebo for the evaluation of efficacy and tolerability of doxycline administered by oral route in patients affected by Creutzfeldt-Jakob disease. - ND	Creutzfeldt-Jakob Disease. MedDRA version: 9.1;Level: LLT;Classification code 10011384;Term: Creutzfeldt-Jakob disease	Trade Name: BASSADO 10CPS 100MG INN or Proposed INN: Doxycycline	ISTITUTO NEUROLOGICO CARLO BESTA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Italy

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

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sponsor

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sponsor

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Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

EUCTR2010-022233-28-IT
(EUCTR)

20/06/2011

05/03/2012

Fatal familial insomnia: preventive treatment with doxycycline of at risk individuals - Doxycycline in FFI individuals

Subjects born between 1958 and 1969 belonging to the Treviso FFI family, tested previously for Prion D178N/129M mutation
MedDRA version: 14.1;Level: SOC;Classification code 10029205;Term: Nervous system disorders;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]

Trade Name: BASSADO
INN or Proposed INN: DOXYCYCLINE HYCLATE

IST. DI RICERCHE FARMACOLOG. M. NEGRI

NULL

Authorised-recruitment may be ongoing or finished

Female: yes
Male: yes

Italy

EUCTR2006-001858-27-IT
(EUCTR)

21/06/2006

12/04/2007

A randomized, double-blind pilot study vs placebo for the evaluation of efficacy and tolerability of doxycline administered by oral route in patients affected by Creutzfeldt-Jakob disease. - ND

Creutzfeldt-Jakob Disease.
MedDRA version: 9.1;Level: LLT;Classification code 10011384;Term: Creutzfeldt-Jakob disease

Trade Name: BASSADO 10CPS 100MG
INN or Proposed INN: Doxycycline

ISTITUTO NEUROLOGICO CARLO BESTA

NULL

Authorised-recruitment may be ongoing or finished

Female: yes
Male: yes

Italy