Home    Back

Target Gene/Pathway💬 Info on mouse-over

e.g. Sirolimus, Adalimumab, MAP2K

ABCDEFGH I JKLMNOPQRSTUVWXYZother

21 / 286 pathways

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related		 KEGG GENES KEGG DRUG DrugBank Disease ID
1 Aldosterone synthesis and secretion 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
2 Calcium signaling pathway 💬
 [1] HRH1 💬 D00665 💬 Chlorpheniramine [1] 14 💬
3 Calcium signaling pathway 💬
 [1] HRH1 💬 D00668 💬 Chlorpheniramine [1] 14 💬
4 Calcium signaling pathway 💬
 [1] HRH1 💬 D07398 💬 Chlorpheniramine [1] 14 💬
5 Calcium signaling pathway 💬
 [1] HRH1 💬 D07803 💬 Chlorpheniramine [1] 14 💬
6 cAMP signaling pathway 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
7 Complement and coagulation cascades 💬
 [1] C5 💬 D03940 💬 Eculizumab [8] 11, 13, 14, 61, 62, 109, 222, 223 💬
8 Coronavirus disease - COVID-19 💬
 [1] C5 💬 D03940 💬 Eculizumab [8] 11, 13, 14, 61, 62, 109, 222, 223 💬
9 Cortisol synthesis and secretion 💬
 [1] KCNA4 💬 D04127 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬
10 Cortisol synthesis and secretion 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
11 Cushing syndrome 💬
 [1] KCNA4 💬 D04127 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬
12 Cushing syndrome 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
13 FoxO signaling pathway 💬
 [1] S1PR1 💬 D10001 💬 Fingolimod [3] 13, 14, 156 💬
14 Hematopoietic cell lineage 💬
 [1] MS4A1 💬 D02994 💬 Rituximab [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
15 Herpes simplex virus 1 infection 💬
 [1] C5 💬 D03940 💬 Eculizumab [8] 11, 13, 14, 61, 62, 109, 222, 223 💬
16 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 D00665 💬 Chlorpheniramine [1] 14 💬
17 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 D00668 💬 Chlorpheniramine [1] 14 💬
18 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 D07398 💬 Chlorpheniramine [1] 14 💬
19 Inflammatory mediator regulation of TRP channels 💬
 [1] HRH1 💬 D07803 💬 Chlorpheniramine [1] 14 💬
20 Neuroactive ligand-receptor interaction 💬
 [1] C5 💬 D03940 💬 Eculizumab [8] 11, 13, 14, 61, 62, 109, 222, 223 💬
21 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 D00665 💬 Chlorpheniramine [1] 14 💬
22 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 D00668 💬 Chlorpheniramine [1] 14 💬
23 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 D07398 💬 Chlorpheniramine [1] 14 💬
24 Neuroactive ligand-receptor interaction 💬
 [1] HRH1 💬 D07803 💬 Chlorpheniramine [1] 14 💬
25 Neuroactive ligand-receptor interaction 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
26 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00292 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
27 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00975 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
28 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01510 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
29 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01615 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
30 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01632 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
31 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01948 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
32 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02174 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
33 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02591 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
34 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02592 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
35 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00407 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
36 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00751 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
37 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00979 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
38 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D05000 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
39 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D05001 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
40 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D05002 💬 Methylprednisolone [44]  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
41 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00472 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
42 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00980 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
43 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00981 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
44 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00982 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
45 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01239 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
46 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01998 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
47 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02156 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
48 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D03301 💬 Prednisolone [40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
49 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00473 💬 Prednisone [47]  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
50 Neuroactive ligand-receptor interaction 💬
 [1] S1PR1 💬 D10001 💬 Fingolimod [3] 13, 14, 156 💬
51 Neutrophil extracellular trap formation 💬
 [1] C5 💬 D03940 💬 Eculizumab [8] 11, 13, 14, 61, 62, 109, 222, 223 💬
52 Pertussis 💬
 [1] C5 💬 D03940 💬 Eculizumab [8] 11, 13, 14, 61, 62, 109, 222, 223 💬
53 Platinum drug resistance 💬
 [2] TOP2A, TOP2B 💬 D00125 💬 Etoposide [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
54 Platinum drug resistance 💬
 [2] TOP2A, TOP2B 💬 D04107 💬 Etoposide [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
55 Prion disease 💬
 [1] C5 💬 D03940 💬 Eculizumab [8] 11, 13, 14, 61, 62, 109, 222, 223 💬
56 Serotonergic synapse 💬
 [1] KCND2 💬 D04127 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬
57 Sphingolipid signaling pathway 💬
 [1] S1PR1 💬 D10001 💬 Fingolimod [3] 13, 14, 156 💬
58 Spinocerebellar ataxia 💬
 [2] KCNC3, KCND3 💬 D04127 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬
59 Staphylococcus aureus infection 💬
 [1] C5 💬 D03940 💬 Eculizumab [8] 11, 13, 14, 61, 62, 109, 222, 223 💬
60 Systemic lupus erythematosus 💬
 [1] C5 💬 D03940 💬 Eculizumab [8] 11, 13, 14, 61, 62, 109, 222, 223 💬

Back to top