66. IgA nephropathy
199 clinical trials,   214 drugs   (DrugBank: 57 drugs),   32 drug target genes,   128 drug target pathways

Searched query = "IgA nephropathy", "IgA nephritis", "Berger disease", "IgA-IgG nephropathy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
14 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2016-004507-31-FR
(EUCTR)
27/01/201702/02/2017N/AN/A - TIGER
MedDRA version: 19.1;Level: PT;Classification code 10021263;Term: IgA nephropathy;System Organ Class: 10038359 - Renal and urinary disorders
Trade Name: METHYLPREDNISOLONE MYLAN Générique
Product Name: METHYLPREDNISOLONE MYLAN Générique
INN or Proposed INN: Methylprednisolone
Other descriptive name: Methylprednisolone
Trade Name: PREDNISONE ARROW 20mg
Product Name: PREDNISONE ARROW 20mg
INN or Proposed INN: PREDNISONE
Other descriptive name: PREDNISONE
Trade Name: PREDNISONE ARROW 5 mg
Product Name: PREDNISONE ARROW 5 mg
INN or Proposed INN: Prednisone 5 mg
Other descriptive name: Prednisone 5 mg
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)NULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
122Phase 3France
2NCT03218852
(ClinicalTrials.gov)
December 20167/12/2016Extended Follow-up of Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA NephropathyAn Extended Follow-up of the Prospective Randomized, Controlled, Open-labeled Trial of Prednisone Plus Cyclophosphamide in Patients With Advanced Stage IgA NephropathyIgA NephropathyDrug: prednisone and cyclophosphamide;Drug: prednisone aloneGuangdong General HospitalNULLActive, not recruiting18 Years70 YearsAll133Phase 4China
3NCT02712697
(ClinicalTrials.gov)
June 201617/11/2015Integrative Medicine of IgA NephropathyTreatment of Shentong Granules Plus Prednisone on Patients With Severe IgA Nephropathy(Ying-deficiency of the Liver and Kidney Pattern): a Randomized, Double-blind,Placebo-controlled Multicentre Clinical TrialPrimary IgA NephropathyDrug: WM (Shentong Granules);Drug: Hormone (prednisone)Shanghai University of Traditional Chinese MedicineRenJi Hospital;Ruijin Hospital;Shanghai 6th People's Hospital;Xinhua Hospital, Shanghai Jiao Tong University School of Medicine;Fudan UniversityNot yet recruiting18 Years70 YearsBoth140N/AChina
4NCT01758120
(ClinicalTrials.gov)
December 201212/12/2012Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA NephropathyA Prospective Randomized, Controlled, Open-labeled Trial of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA NephropathyIgA NephropathyDrug: prednisone plus cyclophosphamide;Drug: Prednisone aloneGuangdong General HospitalNULLActive, not recruiting18 Years70 YearsAll135Phase 4China
5NCT01451710
(ClinicalTrials.gov)
March 20117/10/2011The Effectiveness of Enough Steroids as Inducement Therapy in Minimal Change Disease-like IgA NephropathyThe Effectiveness of Enough Steroids as Inducement Therapy in Minimal Change Disease-like IgA NephropathyIgA NephropathyDrug: Prednisone or PrednisoloneNanjing University School of MedicineNULLCompleted18 Years65 YearsBoth30N/AChina
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6ChiCTR-OPN-16010028
2011-01-012016-11-23Effects of Tripterygium wilfordii induction therapy to IgA nephropathy patients with heavy proteinuriaEffects of Tripterygium wilfordii induction therapy to IgA nephropathy patients with heavy proteinuria IgA nephropathyPrednisone (PRE) group:1mg/kg prednisone once daily;conventional-dose TW (CTW) group:60 mg TW daily;double-dose TW (DTW) group:?????120mg;Yancheng Third People's HospitalNULLCompleted2154BothPrednisone (PRE) group:10;conventional-dose TW (CTW) group:10;double-dose TW (DTW) group:10;NULL
7NCT01269021
(ClinicalTrials.gov)
November 201010/12/2010An Multi-site Prospective Study to Assess the Efficacy and Safety of MMF in the Treatment of Proliferative IgA Nephropathy(IgAN)Research Institute of Nephrology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.IgA Nephropathy (IgAN)Drug: mycophenolate mofetil plus lower dose of Prednisone;Drug: Prednisone in full doseZhi-Hong Liu, M.D.NULLCompleted18 Years60 YearsBoth176N/AChina
8ChiCTR-TRC-13003702
2010-01-012013-10-12Study of Standardized Treatment of Integrative Medicine With the Severe IgA NephropathyStudy of Standardized Treatment of Integrative Medicine With the Severe IgA Nephropathy IgA NephropathyExperimental Group:Chinese Herb Prescription Granule, 6g, Bid, po. 48 weeks;Placebo Comparator:Placebo of Chinese Herb Prescription Granule, 6g, Bid, po. 48 weeks plus prednisone, 0.5mg-1mg/kg/d, po. 48 weeks;Department of Nephrology, Longhua Hospital, Shanghai University of Traditional Chinese MedicineNULLCompleted1860BothExperimental Group:100;Placebo Comparator:10;China
9ChiCTR-TRC-10000824
2010-01-012010-04-06the clinical effect of Fufang Shenyan Tablet on IgA Nephropathy patientsMulticenter, randomized, double-blind, placebo-controlled clinical research of the clinical effect of Fufang Shenyan Tablet on IgA Nephropathy patients IgA Nephropathythe control group:The 24-hour urinary protein 0.5-2.0g: Lotensin 10mg, bid; placebos 2.5g tid; The 24-hour urinary protein 2.0-3.5g: on this basis, combined with prednisone 40mg/d; If patients with hypertension(target blood pressure <=130/80mmHg), used Lotensin 10mg bid alone control it difficultly, give Norvasc 5mg, qd~bid instead; if still poorly controlled, combined with Betaloc 12.5mg, bid;the treatment group:The 24-hour urinary protein 0.5-2.0g: Lotensin 10mg, bid; Fufang Shenyan Tablets 2.5g tid; The 24-hour urinary protein 2.0-3.5g: on this basis, combined with prednisone 40mg/d; If patients with hypertension (target blood pressure <=130/80mmHg), used Lotensin 10mg bid alone control it difficultly, give Norvasc 5mg, qd~bid instead; if still poorly controlled, combined with Betaloc 12.5mg, bid;The First Affiliated Hospital of Xi'an Jiaotong University Medical CollegeNULLCompleted1865Boththe control group:60;the treatment group:60;China
10NCT01879514
(ClinicalTrials.gov)
January 201025/3/2013Study of Standardized Treatment of Integrative Medicine With the Severe IgA NephropathStudy of Standardized Treatment of Integrative Medicine With the Severe IgA NephropathIgA NephropathyDrug: Chinese Herb Prescription Granule plus prednisone;Drug: PlaceboShanghai University of Traditional Chinese MedicineShanghai Sixth People's Hospital;RenJi HospitalRecruiting18 Years60 YearsBoth200N/AChina
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
11NCT00657059
(ClinicalTrials.gov)
September 20078/4/2008Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy (IgAN)A Prospective, Multicenter, Randomized Controlled Trial of Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy (IgAN)IgA NephropathyDrug: irbesartan;Drug: methylprednisolone (MP) or prednisone (pred);Drug: mycophenolate mofetil (MMF)Sun Yat-sen UniversityNULLCompleted14 Years60 YearsAll151Phase 3China
12ChiCTR-TRC-06000004
2006-01-012006-09-14ACEi/ARB alone versus ACEi/ARB plus Steroids in the treatment of primary IgA nephropathy, a randomized multicenter controlled trialACEi/ARB alone versus ACEi/ARB plus Steroids in the treatment of primary IgA nephropathy, a randomized multicenter controlled trial primary IgA nephropathygroup 1:treated with ACEI/ARB( ARB therapy is subjected to patients with cough after use of ACEI) Inhibace (cilazapril): start at 1.25mg/day, increase the dose by 1.25mg/day/week to 2.5-5mg/day Cozaar (losartan): 25~50mg/day, increased to 50~100mg/day Last for one year;group 2:Oral prednisone for 6 mos 0.8mg/kg/day x 8 wks Tapered 0.2mg/kg/day/mo in combination with ACEI/ARB;The First Hospital, Peking UniversityNULLCompleted1665Bothgroup 1:78;group 2:78;China
13NCT00378443
(ClinicalTrials.gov)
January 200619/9/2006ACEi/ARB Alone Versus ACEi/ARB Plus Steroids in the Treatment of Primary IgA Nephropathy, a RCTGlomerulonephritis, IGADrug: prednisone + Inhibace/Cozaar;Drug: Inhibace/CozaarPeking UniversityNULLActive, not recruiting16 Years65 YearsBothN/ANULL
14NCT01392833
(ClinicalTrials.gov)
December 19995/7/2011Steroids and Azathioprine in Advanced IgANSteroids and Azathioprine in Early and Advanced IgA Nephropathy: Amendments to a Prospective Randomised Multicenter TrialIgA Nephropathy;Chronic Kidney DiseaseDrug: methylprednisolone;Drug: azathioprine;Drug: prednisoneA. Manzoni HospitalNULLCompleted16 Years70 YearsBoth46Phase 3NULL