10. Charcot-Marie-Tooth disease
31 clinical trials,   38 drugs   (DrugBank: 9 drugs),   11 drug target genes,   14 drug target pathways

Searched query = "Charcot-Marie-Tooth disease", "CMT"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
7 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
PhaseCountries
1JPRN-jRCTs031190109
03/10/201903/10/2019Ascorbic acid treatment for childhood Charcot-Marie-Tooth disease 1AAscorbic acid treatment for childhood Charcot-Marie-Tooth disease 1A - Ascorbic acid for CMT1A Charcot-Marie-Tooth disease type 1A
CMT1A;G600
ascorbic acid dayly intakeFUJII KATSUNORINULLRecruitingNot applicable< 18age oldBoth12Phase 2Japan
2JPRN-UMIN000036332
2019/06/1528/03/2019Ascorbic acid treatment for Charcot-Marie-Tooth disease type 1AAscorbic acid treatment for Charcot-Marie-Tooth disease type 1A - Ascorbic acid treatment for CMT1A Charcot-Marie-Tooth diease type 1AAscorbic acid treatment: 20mg/kg/day, daylyChiba UniversityNULLPending1years-oldNot applicableMale and Female10Phase 1Japan
3NCT00484510
(ClinicalTrials.gov)
April 20078/6/2007High Dose Ascorbic Acid Treatment of CMT1AA Randomized, Placebo-controlled, Double Masked 120 Subject Futility Design Clinical Trial of Ascorbic Acid Treatment of Charcot Marie Tooth Disease Type 1A.Charcot-Marie-Tooth Disease, Type IaDrug: Ascorbic acid (Vitamin C);Drug: placeboWayne State UniversityMuscular Dystrophy Association;Charcot-Marie-Tooth AssociationCompleted13 Years70 YearsBoth110Phase 2;Phase 3United States
4NCT00271635
(ClinicalTrials.gov)
January 20063/1/2006Ascorbic Acid Treatment in CMT1A Trial (AATIC)Phase 2 Study of Ascorbic Acid Treatment in Charcot-Marie-Tooth Type 1ACharcot-Marie-Tooth Disease;Hereditary Motor and Sensory NeuropathiesDrug: Placebo;Drug: ascorbic acidAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NULLCompleted12 Years25 YearsBoth13Phase 2Netherlands
5EUCTR2006-000032-27-IT
(EUCTR)
19/10/200514/03/2006MULTICENTRE RANDOMISED DOUBLE BLIND PLACEBO CONTROLLED TRIAL OF LONG-TERM ASCORBIC ACID TREATMENT IN CHARCOT-MARIE-TOOTH DISEASE TYPE 1A CMT-TRIAAL CMT-TRial Italian with Ascorbic Acid Long term - CMT-TRIAALMULTICENTRE RANDOMISED DOUBLE BLIND PLACEBO CONTROLLED TRIAL OF LONG-TERM ASCORBIC ACID TREATMENT IN CHARCOT-MARIE-TOOTH DISEASE TYPE 1A CMT-TRIAAL CMT-TRial Italian with Ascorbic Acid Long term - CMT-TRIAAL Charcot-Marie-Tooth disease type 1A CMT1A
MedDRA version: 6.1;Level: HLGT;Classification code 10034606
Trade Name: CEBION 500MG 20CPR MAST.ARAN
INN or Proposed INN: ACIDO ASCORBICO DC.IT
INN or Proposed INN: SODIO ASCORBATO DC.IT
ISTITUTO NEUROLOGICO CARLO BESTANULLNot RecruitingFemale: yes
Male: yes
202Italy
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6JPRN-UMIN000001535
2005/04/0101/01/2009A multicenter, randomized open trial of ascorbic acid treatment in Charcot-Marie-Tooth disease type 1A Charcot-Marie-Tooth disease 1AAscorbic acid (AA) treatment group
(12 weeks oral AA (20mg/kg/day)
no AA treatment group
New treatment strategies for intractable neuropathies based on its pathomechanism.The Research Grant 19A-5 for Nervous and Mental Disorders from the Ministry of Health, Labour and Welfare.NULLComplete: follow-up complete15years-old75years-oldMale and Female60Phase 1;Phase 2Japan
7EUCTR2004-004501-24-IT
(EUCTR)
22/12/200413/02/2007Multicentre, randomised, double blind, placebo controlled trial of ascorbic acid treatment in Charcot-Marie-Tooth Disease Type 1A CMT1A .Multicentre, randomised, double blind, placebo controlled trial of ascorbic acid treatment in Charcot-Marie-Tooth Disease Type 1A CMT1A . Charcot-Marie-Tooth Disease Type 1A CMT1A .
MedDRA version: 6.1;Level: HLT;Classification code 10022031
Trade Name: CEBION 500*20CPR MAST 500MG
Product Name: ACIDO ASCORBICO
INN or Proposed INN: Ascorbic acid vit C
ISTITUTO NEUROLOGICO CARLO BESTANULLNot RecruitingFemale: yes
Male: yes
200Italy