167. Marfan syndrome
19 clinical trials,   38 drugs   (DrugBank: 10 drugs),   10 drug target genes,   49 drug target pathways

Searched query = "Marfan syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
3 trials found
No.TrialIDDate_
enrollment
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Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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agemin
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agemax
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PhaseCountries
1NCT01949233
(ClinicalTrials.gov)
October 20136/8/2013The Oxford Marfan TrialA Randomised, Double-blind, Placebo-controlled Pilot Trial of Irbesartan, Doxycycline and a Combination on Markers of Vascular Dysfunction in the Marfan Syndrome, Using Cardiovascular Magnetic Resonance ImagingMarfan SyndromeDrug: Irbesartan 150-300mg capsules daily for 6 months;Drug: Doxycycline 100-200mg capsules daily for 6 months;Drug: Doxycycline placebo capsules daily for 6 months;Drug: Irbesartan placebo capsules daily for 6 monthsUniversity of OxfordOxford University Hospitals NHS TrustRecruiting13 YearsN/ABoth56Phase 2United Kingdom
2EUCTR2010-023612-14-GB
(EUCTR)
08/03/201320/12/2012The Oxford Marfan Trial A randomised, double-blind, placebo-controlled pilot trial of irbesartan, doxycycline and a combination on markers of vascular dysfunction in the Marfan syndrome, using cardiovascular magnetic resonance imaging - The Oxford Marfan Trial Version 1.0 Marfan syndrome.
MedDRA version: 14.1;Level: PT;Classification code 10026829;Term: Marfan's syndrome;System Organ Class: 10010331 - Congenital, familial and genetic disorders ;Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Clinical Trials and Research GovernanceNULLNot Recruiting Female: yes
Male: yes
56Phase 2United Kingdom
3EUCTR2010-019302-16-GB
(EUCTR)
13/09/201017/08/2010A prospective, randomised, placebo-controlled, double blind, multi-centre study of the effects of Irbesartan on aortic dilatation in Marfan syndromeA prospective, randomised, placebo-controlled, double blind, multi-centre study of the effects of Irbesartan on aortic dilatation in Marfan syndrome - The AIMS Study Marfan SyndromeRoyal Brompton and Harefield NHS Foundation TrustNULLNot Recruiting Female: yes
Male: yes
490Phase 3United Kingdom