168. Ehlers-Danlos syndrome
7 clinical trials,   16 drugs   (DrugBank: 8 drugs),   9 drug target genes,   54 drug target pathways

Searched query = "Ehlers-Danlos syndrome", "EDS", "cEDS", "hEDS", "clEDS", "vEDS", "kEDS", "aEDS", "dEDS", "DDEDS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04036305
(ClinicalTrials.gov)
July 26, 201925/7/2019Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy VolunteersLocal Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy VolunteersEhlers-Danlos Syndrome;Anesthesia, LocalDrug: 0.9% Sodium Chloride Injection;Drug: Lidocaine Injection 2%;Drug: Bupivacaine Injection 0.5%Vanderbilt University Medical CenterUniversity of CalgaryEnrolling by invitation18 YearsN/AAll230United States
2NCT02597361
(ClinicalTrials.gov)
January 201623/10/2015Angiotensin II Receptor Blockade in Vascular Ehlers Danlos Syndrome (ARCADE)Angiotensin II Receptor Blockade in Vascular Ehlers Danlos Syndrome: a Double Blind, Randomized, Placebo Controlled, Multicenter Trial.Ehlers-Danlos Syndrome, Vascular TypeDrug: Irbesartan;Drug: PlaceboAssistance Publique - Hôpitaux de ParisMinistry of Health, FranceCompleted18 Years70 YearsAll61Phase 3France
3EUCTR2015-001065-76-FR
(EUCTR)
28/09/201508/09/2015N/AN/A - ARCADE
MedDRA version: 18.0;Level: PT;Classification code 10014316;Term: Ehlers-Danlos syndrome;System Organ Class: 10010331 - Congenital, familial and genetic disorders
Trade Name: IRBESARTAN
Product Name: IRBESARTAN
INN or Proposed INN: irbesartan
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)NULLNot RecruitingFemale: yes
Male: yes
169Phase 3France
4NCT01446783
(ClinicalTrials.gov)
September 201127/9/2011IGF-I Stimulation of Collagen Synthesis in Ehlers-Danlos PatientsIGF-I Stimulation of Collagen Synthesis in Ehlers-Danlos PatientsEhlers-Danlos Syndrome, ClassicDrug: mecasermin;Drug: SalineBispebjerg HospitalNULLCompleted18 YearsN/ABoth15N/ADenmark
5NCT01307527
(ClinicalTrials.gov)
November 20081/3/2011Riboflavin Corneal Crosslinking for Brittle Cornea Syndrome and Ehlers-Danlos Syndrome Type VIBrittle Cornea Syndrome;Ehlers-Danlos Syndrome Type 6Drug: Riboflavin;Device: Kera-XHadassah Medical OrganizationNULLEnrolling by invitation18 YearsN/ABoth1N/AIsrael
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6NCT00190411
(ClinicalTrials.gov)
October 200313/9/2005Celiprolol in Patients With Ehlers-Danlos Syndrome, Vascular TypePrevention of Vascular Complications by BetaBlocker Treatment in Vascular Ehlers-Danlos SyndromeEHLERS-DANLOS SYNDROME, TYPE IV, AUTOSOMAL DOMINANT;CHROMOSOME 2q31.2 DELETION SYNDROMEDrug: celiprolol;Drug: ControlAssistance Publique - Hôpitaux de ParisAventis PharmaceuticalsCompleted15 Years65 YearsBoth54Phase 4France
7NCT00001966
(ClinicalTrials.gov)
January 200018/1/2000Mind-Body Therapy for Pain in Ehlers-Danlos SyndromeA Pilot Study of Mind-Body Therapy for Chronic Pain in Ehlers-Danlos SyndromeEhlers-Danlos Syndrome;PainDrug: Mind-body therapyNational Human Genome Research Institute (NHGRI)NULLCompletedN/AN/ABoth40Phase 2United States