224. Purpura nephritis
10 clinical trials, 41 drugs (DrugBank: 19 drugs), 15 drug target genes, 56 drug target pathways
Searched query = "Purpura nephritis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04623866 (ClinicalTrials.gov) | November 1, 2020 | 25/10/2020 | Study on the Treatment of Children With Purpura Nephritis With Huaiqihuang Granules | A Single Center Randomized Controlled Clinical Study on the Treatment of Children With Purpura Nephritis With Huaiqihuang Granules | Henoch Schönlein Purpura Nephritis | Drug: Huaiqinhuang;Drug: valsartan | The Children's Hospital of Zhejiang University School of Medicine | NULL | Not yet recruiting | 6 Years | 14 Years | All | 10 | Early Phase 1 | China |
| 2 | ChiCTR2000037540 | 2020-09-30 | 2020-08-28 | Effects and safety of MMF combined with short course steriods therapy in children Henoch-Schnlein purpura nephritis | Effects and safety of MMF combined with short course steriods therapy in children Henoch-Schnlein purpura nephritis | children Henoch-Schnlein purpura nephritis | experimental group:mycophenolate mofetil;control group:traditional course steriod; | Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine | NULL | Pending | 2 | 14 | Both | experimental group:30;control group:30; | N/A | China |
| 3 | ChiCTR1800017046 | 2018-07-15 | 2018-07-10 | The research of Gd - IgA1 with purpura nephritis | The research of Gd - IgA1 with purpura nephritis | Henoch-Schnlein purpura nephritis;D69.005+ | Gold Standard:Allergic purpura diagnostic criteria: 1) the tangibility purpura; 2) the onset age < 20 years old; 3) with acute abdominal pain; 4) biopsy showed small veins and arteries around a neutrophil infiltration. In the above four standard, conform to article 2 or above can be diagnosed as allergic purpura. Purpur;Index test:Gd-IgA1, IgA, IgG, C3; | College of Pediatrics, University of South China/Children's Hospital of Hu'nan Province | NULL | Recruiting | 1 | 14 | Both | Target condition:250;Difficult condition:24 | China | |
| 4 | NCT02878018 (ClinicalTrials.gov) | September 2016 | 17/8/2016 | Cohort Study on Traditional Chinese Medicine Diagnosis and Treatment of Children With Henoch-Schonlein Purpura Nephritis | Cohort Study on Traditional Chinese Medicine Diagnosis and Treatment of Children With Henoch-Schonlein Purpura Nephritis | Henoch-Schonlein Purpura Nephritis | Drug: Qi-Ji Shen-Kang formula; Zhu-Bai formula; Yu-Shen formula;Drug: angiotensin-converting enzyme (ACE) inhibitor; adrenergic receptor binder (ARB); adrenal cortical hormone; Tripterygium wilfordii polyglycosidium; immunosuppressant | Liaoning University of Traditional Chinese Medicine | First Hospital of China Medical University;Shengjing Hospital | Active, not recruiting | 5 Years | 18 Years | All | 600 | China | |
| 5 | ChiCTR-IPC-16008619 | 2016-07-01 | 2016-06-09 | Efficacy of Mizoribine for Children with Henoch-Schnlein Purpura Nephritis Presenting with Nephrotic Range Proteinuria: A Prospective and Controlled Study in China | Efficacy of Mizoribine for Children with Henoch-Schnlein Purpura Nephritis Presenting with Nephrotic Range Proteinuria: A Prospective and Controlled Study in China | Children with Henoch-Sch?nlein Purpura Nephritis | mizoribine:5 mg/kg body weight daily (maximum total dose: 150 mg); | Nanjing General Hospital of Nanjing Military Command | NULL | Pending | 5 | 18 | Both | mizoribine:180; | China | |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | NCT03222687 (ClinicalTrials.gov) | September 1, 2015 | 7/7/2017 | Tacrolimus in Children With Henoch-Schönlein Purpura Nephritis | Off-label Use of Tacrolimus in Children With Henoch-Schönlein Purpura Nephritis: Effectiveness and Safety | Henoch-Schönlein Purpura Nephritis | Drug: tacrolimus;Drug: prednisone | Shandong University | NULL | Completed | N/A | 18 Years | All | 25 | Phase 4 | NULL |
| 7 | NCT02532777 (ClinicalTrials.gov) | August 2015 | 20/8/2015 | The Research of Standard Diagnosis and Treatment for HSPN in Children | The Research of Standard Diagnosis and Treatment for Henoch-Schonlein Purpura Nephritis in Children | Henoch-Schoenlein Purpura Nephritis | Drug: Prednisone;Drug: Cyclophosphamide(CTX);Drug: Mycophenolate mofetil(MMF);Drug: Leflunomide(LEF);Drug: Angiotensin-converting enzyme inhibitor(ACEI);Drug: Methylprednisolone | Nanjing Children's Hospital | NULL | Recruiting | 2 Years | 16 Years | All | 100 | Phase 2 | China |
| 8 | NCT02532790 (ClinicalTrials.gov) | August 2015 | 20/8/2015 | The Research of Standard Diagnosis and Treatment for HSPN With Mild Proteinuria in Children | The Research of Standard Diagnosis and Treatment for Henoch-Schonlein Purpura Nephritis With Mild Proteinuria in Children | Henoch-Schoenlein Purpura Nephritis | Drug: Prednisone;Drug: ACEI | Nanjing Children's Hospital | NULL | Recruiting | 2 Years | 16 Years | All | 100 | Phase 2 | China |
| 9 | NCT03591471 (ClinicalTrials.gov) | September 2014 | 9/12/2014 | Study on Children Henoch-Schönlein Purpura Nephritis With TCM Multistep Treatment | Demonstrated Study on Children Henoch-Schönlein Purpura Nephritis With Multistep Treatment of Traditional Chinese Medicine Combined Disease and Syndrome Differentiation | Henoch-Schönlein Purpura Nephritis | Drug: Glycosides Of Tripterygium Wilfordii Hook(GTW);Drug: Sulfotanshinone Sodium Injection;Drug: Chinese herbs based on syndrome differentiation;Drug: Prednisone Acetate Tablets;Drug: Benazepril Hydrochloride Tablets;Drug: Low Molecular Weight Heparin Calcium Injection;Drug: Dipyridamole Tab 25 MG;Drug: Chinese medicine placebo | Henan University of Traditional Chinese Medicine | Peking University First Hospital;Children's Hospital of Fudan University;Shanghai Children's Hospital;Chengdu University of Traditional Chinese Medicine;Affiliated Hospital of Yunnan University of Traditional Chinese Medicine | Unknown status | 2 Years | 18 Years | All | 500 | Phase 1;Phase 2 | China |
| 10 | NCT00301613 (ClinicalTrials.gov) | January 2003 | 10/3/2006 | Mycophenolate Mofetil (MMF) Versus Intravenous CTX Pulses in the Treatment of Adult Severe HSPN | MMF Versus Intravenous CTX Pulses in the Treatment of Adult Severe Henoch-Schonlein Purpura Nephritis | Henoch-Schoenlein Purpura;Nephritis | Drug: Mycophenolate mofetil | Nanjing University School of Medicine | NULL | Completed | 16 Years | 50 Years | Both | 60 | N/A | China |