230. Alveolar hypoventilation syndrome
8 clinical trials,   11 drugs   (DrugBank: 5 drugs),   18 drug target genes,   27 drug target pathways

Searched query = "Alveolar hypoventilation syndrome", "AHS", "Hypoventilation syndrome", "OHS", "CCHS", "Idiopathic central alveolar hypoventilation", "ICAH"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04108819
(ClinicalTrials.gov)
October 30, 201926/9/2019Ketogenic Diet for Obesity Hypoventilation SyndromeKetogenic Diet for Obesity Hypoventilation SyndromeObesity Hypoventilation Syndrome;Ketogenic Dieting;Hypercapnic Respiratory FailureDietary Supplement: Ketogenic DietJohns Hopkins UniversityNULLRecruiting18 Years75 YearsAll10N/AUnited States
2NCT01964339
(ClinicalTrials.gov)
October 9, 201314/10/2013Obesity Hypoventilation Syndrome Prevalence StudyObesity Hypoventilation Syndrome Prevalence StudyObesity Hypoventilation SyndromeOther: BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (venous blood gas and metabolic panel) and data collection from PSG study.;Other: BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (arterial blood gas and metabolic panel) and data collection from PSG study.Philips RespironicsNULLTerminated21 YearsN/AAll44United States
3NCT01500473
(ClinicalTrials.gov)
February 201222/12/2011Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation SyndromeTherapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation SyndromeCongenital Central Hypoventilation SyndromeDrug: DesogestrelChildren's Hospital Los AngelesNULLNot yet recruiting16 Years50 YearsFemale8N/AUnited States
4NCT01499485
(ClinicalTrials.gov)
November 201120/12/2011Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation.Effects of Acetazolamide on the Duration of Mechanical Ventilation in Patients With Metabolic Alkalosis. Phase III Multicenter Double-blinded Clinical Trial.Pulmonary Disease, Chronic Obstructive;Obesity Hypoventilation Syndrome;Metabolic AlkalosisDrug: Acetazolamide;Drug: PlaceboHospital Son LlatzerNULLCompleted18 YearsN/ABoth140Phase 3Spain
5NCT01243697
(ClinicalTrials.gov)
April 201117/11/2010Assessment of Desogestrel in Ondine SyndromeAssessment of Desogestrel for a Pharmacological Recovery of Ventilatory Activity in Congenital Central Hypoventilation Syndrome - Ondine SyndromeOndine SyndromeDrug: desogestrelAssistance Publique - Hôpitaux de ParisNULLCompleted10 Years60 YearsFemale6Phase 2;Phase 3France
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6ChiCTR-DDT-11001215
2010-07-012011-03-05Double position CT investigation of OSAHSDouble position CT investigation of OSAHS Obstructive sleep apnea hypoventilation syndromeGold Standard:;Index test:;First Hospital of Peking universityNULLCompletedBothTarget condition:0;Difficult condition:0China
7EUCTR2005-005950-33-SE
(EUCTR)
07/06/200610/04/2006Studie av Domperidon och barn med kongenitalt centralt hypoventilationssyndrom. - DOMPCCHSSWE1Studie av Domperidon och barn med kongenitalt centralt hypoventilationssyndrom. - DOMPCCHSSWE1 Congenital central hypoventilation syndrome, CCHS or Ondine's curse.Trade Name: Motilium
Product Name: Motilium
INN or Proposed INN: Domperidone
Karolinska UniversitetssjukhusetNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
Sweden
8EUCTR2011-000989-35-FR
(EUCTR)
06/05/2011N/AN/A - RESPIRONDINE
MedDRA version: 14.0;Level: PT;Classification code 10066131;Term: Congenital central hypoventilation syndrome;System Organ Class: 10010331 - Congenital, familial and genetic disorders
Trade Name: Cerazette
Product Name: Cerazette
INN or Proposed INN: Désogestrel
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)NULLNAFemale: yes
Male: no
Phase 2France